Kallikrein 14 (KLK14) (NM_022046) Human Untagged Clone

CAT#: SC123983

KLK14 (untagged)-Human kallikrein-related peptidase 14 (KLK14)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KLK14
• Synonyms: KLK-L6
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC123983 sequence for NM_022046 edited (data generated by NextGen Sequencing)
  ATGTCCCTGAGGGTCTTGGGCTCTGGGACCTGGCCCTCAGCCCCTAAAATGTTCCTCCTG
  CTGACAGCACTTCAAGTCCTGGCTATAGCCATGACACAGAGCCAAGAGGATGAGAACAAG
  ATAATTGGTGGCCATACGTGCACCCGGAGCTCCCAGCCGTGGCAGGCGGCCCTGCTGGCG
  GGTCCCAGGCGCCGCTTCCTCTGCGGAGGCGCCCTGCTTTCAGGCCAGTGGGTCATCACT
  GCTGCTCACTGCGGCCGCCCGATCCTTCAGGTTGCCCTGGGCAAGCACAACCTGAGGAGG
  TGGGAGGCCACCCAGCAGGTGCTGCGCGTGGTTCGTCAGGTGACGCACCCCAACTACAAC
  TCCCGGACCCACGACAACGACCTCATGCTGCTGCAGCTACAGCAGCCCGCACGGATCGGG
  AGGGCAGTCAGGCCCATTGAGGTCACCCAGGCCTGTGCCAGCCCCGGGACCTCCTGCCGA
  GTGTCAGGCTGGGGAACTATATCCAGCCCCATCGCCAGGTACCCCGCCTCTCTGCAATGC
  GTGAACATCAACATCTCCCCGGATGAGGTGTGCCAGAAGGCCTATCCTAGAACCATCACG
  CCTGGCATGGTCTGTGCAGGAGTTCCCCAGGGCGGGAAGGACTCTTGTCAGGGTGACTCT
  GGGGGACCCCTGGTGTGCAGAGGACAGCTCCAGGGCCTCGTGTCTTGGGGAATGGAGCGC
  TGCGCCCTGCCTGGCTACCCCGGTGTCTACACCAACCTGTGCAAGTACAGAAGCTGGATT
  GAGGAAACGATGCGGGACAAATGA
  
  Clone variation with respect to NM_022046.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022046 unedited
  CAGATTTTGTATACGACTCACTATAGGGCGGCNCGCGAATTCGCACGAGCTCCTTCCTTC
  ATCAAGACATCAAGGAGGGACCTGTGCCCTGCTCCACATCCTCCCACCTGCCGCCCGCAG
  AGCCTGCAGGCCCCGCCCCCCTCGTCTCTGGTCCCTACCTCTCTGCTGTGTCTTCATGTC
  CCTGAGGGTCTTGGGCTCTGGGACCTGGCCCTCAGCCCCTAAAATGTTCCTCCTGCTGAC
  AGCACTTCAAGTCCTGGCTATAGCCATGACACAGAGCCAAGAGGATGAGAACAAGATAAT
  TGGTGGCCATACGTGCACCCGGAGCTCCCAGCCGTGGCAGGCGGCCCTGCTGGCGGGTCC
  CAGGCGCCGCTTCCTCTGCGGAGGCGCCCTGCTTTCAGGCCAGTGGGTCATCACTGCTGC
  TCACTGCGGCCGCCCGATCCTTCANGTTGCCCTGGGCAAGCACAACCTGAGGAGGTGGGA
  GGCCACCCAGCAGGTGCTGCGCGTGGTTCGTCAGGTGACGCACCCCAACTACAACTCCCG
  GACCCACGACAACGACCTCATGCTGCTGCAGTTCCGCAGCCCGCACGGATCAGGAGGGCA
  GTCAGGCCCATTGAAGTCACCCCAGCCTGTGCCAGCCCCGGGACCTCCTGCCAAGTGCAA
  GCTGGGAACTATTTCCAGCCCCATTGCCAGTACCCCGCCTCTCTGCATGCCGGAACCTTA
  ACATCTCCCCGAATGAAGGTGCCATAAGGCCTATTCCTAGAACATAACGCCTGGCATGGT
  TCTTGGCAGAAGATCCCCCCGGGCCGGAAAGAACTCTTTTCCAGGGGACCTTGGGGGAAC
  CCCGGGTTGGCCAAGGAAAACCCCGGGCCCTTCTCATTGGGAAATGGACCCTTCCCCCAC
  CCTGTCATCCCAGGTGTTACCCCAACTCGGCCAAATCAAAAACG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_022046 unedited
  TGGGTGGTTNNNNTTTGCCTGGGTGGCACTTCCAGGCCAGGAGAGGCACTGGGGAGGGGT
  CACAGGGATGCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGA
  GTCGAGTTTTTTTTTTTTTTTTTTTTTTTCCATTTTTATTGTCATTATTTATTCGGTTTT
  TAGAGACACTAAGCGTGTTAAAAATTGTCGTCTTTGGAATACAATGCCGGTTTAAGGGGT
  CTGTGCTCCTGCCCTCTGTGCCTCCGGTCTTGAGTAGTGATGGTGACACAGCAAGGGTGG
  GGGCTTGGTGGGGAGAAAACGCCTGAAGCAACTGCTCTGGGAAAGGAGAGATCAGAGCCG
  GAGTAAAGATCAGGATGCTGGGGACTGGGGCTCCTGTGGGTTGAGGAGGAGGGGCTGGGC
  CTGGACTCCTGGGTCTAAGGAGGAGGGGCTGGGGGACTGGGGCTCCTGGGGTTGGGGAGG
  AGGGGCTGGGCCTGGATTCCTGGGGCTGGGGAGGAGGGGCTGGGGGCCTGGACTCCTGGG
  CTGAGGGAGGAGGGACTGGGGCCCGGACTTCTTGGTTTGAGGGAGGAGGGGCTGGGGGCC
  TGGACTCCCGGTCTGAAGGGGGAGGGGCTGGGCTCGGACTCTTGGGTCTTGGGGGAAGGG
  GTTTGGTCCTGCCTTCCTGTTCATATTGAGAGTGCTTTGGTGCTGAACTCTTCGTCATAG
  CCAACGTACTTCTAAGGATCAATTTTTCGTATTTCGTAAAACGTGAGGCAGAGGT
  
• Restriction Sites: Please inquire
• ACCN: NM_022046
• ORF Size: 756 bp
• Insert Size: 1500
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_022046.3, NP_071329.1
• RefSeq Size: 1459
• RefSeq ORF: 756
• Locus ID: 43847
• Protein Families: Druggable Genome, Protease, Secreted Protein
• Gene Summary: This gene encodes a member of the kallikrein subfamily of serine proteases that have diverse physiological functions such as regulation of blood pressure and desquamation. The altered expression of this gene is implicated in the progression of different cancers including breast and prostate tumors. The encoded protein is a precursor that is proteolytically processed to generate the functional enzyme. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
  Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1-3 all encode the same protein.