Kallikrein 14 (KLK14) (NM_022046) Human Untagged Clone

CAT#: SC123983

KLK14 (untagged)-Human kallikrein-related peptidase 14 (KLK14)


  "NM_022046" in other vectors (7)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol KLK14
Synonyms KLK-L6
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC123983 sequence for NM_022046 edited (data generated by NextGen Sequencing)
ATGTCCCTGAGGGTCTTGGGCTCTGGGACCTGGCCCTCAGCCCCTAAAATGTTCCTCCTG
CTGACAGCACTTCAAGTCCTGGCTATAGCCATGACACAGAGCCAAGAGGATGAGAACAAG
ATAATTGGTGGCCATACGTGCACCCGGAGCTCCCAGCCGTGGCAGGCGGCCCTGCTGGCG
GGTCCCAGGCGCCGCTTCCTCTGCGGAGGCGCCCTGCTTTCAGGCCAGTGGGTCATCACT
GCTGCTCACTGCGGCCGCCCGATCCTTCAGGTTGCCCTGGGCAAGCACAACCTGAGGAGG
TGGGAGGCCACCCAGCAGGTGCTGCGCGTGGTTCGTCAGGTGACGCACCCCAACTACAAC
TCCCGGACCCACGACAACGACCTCATGCTGCTGCAGCTACAGCAGCCCGCACGGATCGGG
AGGGCAGTCAGGCCCATTGAGGTCACCCAGGCCTGTGCCAGCCCCGGGACCTCCTGCCGA
GTGTCAGGCTGGGGAACTATATCCAGCCCCATCGCCAGGTACCCCGCCTCTCTGCAATGC
GTGAACATCAACATCTCCCCGGATGAGGTGTGCCAGAAGGCCTATCCTAGAACCATCACG
CCTGGCATGGTCTGTGCAGGAGTTCCCCAGGGCGGGAAGGACTCTTGTCAGGGTGACTCT
GGGGGACCCCTGGTGTGCAGAGGACAGCTCCAGGGCCTCGTGTCTTGGGGAATGGAGCGC
TGCGCCCTGCCTGGCTACCCCGGTGTCTACACCAACCTGTGCAAGTACAGAAGCTGGATT
GAGGAAACGATGCGGGACAAATGA

Clone variation with respect to NM_022046.4
>OriGene 5' read for NM_022046 unedited
CAGATTTTGTATACGACTCACTATAGGGCGGCNCGCGAATTCGCACGAGCTCCTTCCTTC
ATCAAGACATCAAGGAGGGACCTGTGCCCTGCTCCACATCCTCCCACCTGCCGCCCGCAG
AGCCTGCAGGCCCCGCCCCCCTCGTCTCTGGTCCCTACCTCTCTGCTGTGTCTTCATGTC
CCTGAGGGTCTTGGGCTCTGGGACCTGGCCCTCAGCCCCTAAAATGTTCCTCCTGCTGAC
AGCACTTCAAGTCCTGGCTATAGCCATGACACAGAGCCAAGAGGATGAGAACAAGATAAT
TGGTGGCCATACGTGCACCCGGAGCTCCCAGCCGTGGCAGGCGGCCCTGCTGGCGGGTCC
CAGGCGCCGCTTCCTCTGCGGAGGCGCCCTGCTTTCAGGCCAGTGGGTCATCACTGCTGC
TCACTGCGGCCGCCCGATCCTTCANGTTGCCCTGGGCAAGCACAACCTGAGGAGGTGGGA
GGCCACCCAGCAGGTGCTGCGCGTGGTTCGTCAGGTGACGCACCCCAACTACAACTCCCG
GACCCACGACAACGACCTCATGCTGCTGCAGTTCCGCAGCCCGCACGGATCAGGAGGGCA
GTCAGGCCCATTGAAGTCACCCCAGCCTGTGCCAGCCCCGGGACCTCCTGCCAAGTGCAA
GCTGGGAACTATTTCCAGCCCCATTGCCAGTACCCCGCCTCTCTGCATGCCGGAACCTTA
ACATCTCCCCGAATGAAGGTGCCATAAGGCCTATTCCTAGAACATAACGCCTGGCATGGT
TCTTGGCAGAAGATCCCCCCGGGCCGGAAAGAACTCTTTTCCAGGGGACCTTGGGGGAAC
CCCGGGTTGGCCAAGGAAAACCCCGGGCCCTTCTCATTGGGAAATGGACCCTTCCCCCAC
CCTGTCATCCCAGGTGTTACCCCAACTCGGCCAAATCAAAAACG
>OriGene 3' read for NM_022046 unedited
TGGGTGGTTNNNNTTTGCCTGGGTGGCACTTCCAGGCCAGGAGAGGCACTGGGGAGGGGT
CACAGGGATGCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGA
GTCGAGTTTTTTTTTTTTTTTTTTTTTTTCCATTTTTATTGTCATTATTTATTCGGTTTT
TAGAGACACTAAGCGTGTTAAAAATTGTCGTCTTTGGAATACAATGCCGGTTTAAGGGGT
CTGTGCTCCTGCCCTCTGTGCCTCCGGTCTTGAGTAGTGATGGTGACACAGCAAGGGTGG
GGGCTTGGTGGGGAGAAAACGCCTGAAGCAACTGCTCTGGGAAAGGAGAGATCAGAGCCG
GAGTAAAGATCAGGATGCTGGGGACTGGGGCTCCTGTGGGTTGAGGAGGAGGGGCTGGGC
CTGGACTCCTGGGTCTAAGGAGGAGGGGCTGGGGGACTGGGGCTCCTGGGGTTGGGGAGG
AGGGGCTGGGCCTGGATTCCTGGGGCTGGGGAGGAGGGGCTGGGGGCCTGGACTCCTGGG
CTGAGGGAGGAGGGACTGGGGCCCGGACTTCTTGGTTTGAGGGAGGAGGGGCTGGGGGCC
TGGACTCCCGGTCTGAAGGGGGAGGGGCTGGGCTCGGACTCTTGGGTCTTGGGGGAAGGG
GTTTGGTCCTGCCTTCCTGTTCATATTGAGAGTGCTTTGGTGCTGAACTCTTCGTCATAG
CCAACGTACTTCTAAGGATCAATTTTTCGTATTTCGTAAAACGTGAGGCAGAGGT
Restriction Sites Please inquire     
ACCN NM_022046
ORF Size 756 bp
Insert Size 1500
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq NM_022046.3, NP_071329.1
RefSeq Size 1459
RefSeq ORF 756
Locus ID 43847
Protein Families Druggable Genome, Protease, Secreted Protein
Gene Summary This gene encodes a member of the kallikrein subfamily of serine proteases that have diverse physiological functions such as regulation of blood pressure and desquamation. The altered expression of this gene is implicated in the progression of different cancers including breast and prostate tumors. The encoded protein is a precursor that is proteolytically processed to generate the functional enzyme. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1-3 all encode the same protein.

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