UGT2B15 (NM_001076) Human Untagged Clone

CAT#: SC123996

UGT2B15 (untagged)-Human UDP glucuronosyltransferase 2 family, polypeptide B15 (UGT2B15)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UGT2B15
• Synonyms: HLUG4; UDPGT 2B8; UDPGT2B15; UDPGTH3; UGT2B8
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC123996 sequence for NM_001076 edited (data generated by NextGen Sequencing)
  ATGTCTCTGAAATGGACGTCAGTCTTTCTGCTGATACAGCTCAGTTGTTACTTTAGCTCT
  GGAAGCTGTGGAAAGGTGCTAGTGTGGCCCACAGAATACAGCCATTGGATAAATATGAAG
  ACAATCCTGGAAGAGCTTGTTCAGAGGGGTCATGAGGTGACTGTGTTGACATCTTCGGCT
  TCTACTCTTGTCAATGCCAGTAAATCATCTGCTATTAAATTAGAAGTTTATCCTACATCT
  TTAACTAAAAATGATTTGGAAGATTCTCTTCTGAAAATTCTCGATAGATGGATATATGGT
  GTTTCAAAAAATACATTTTGGTCATATTTTTCACAATTACAAGAATTGTGTTGGGAATAT
  TATGACTACAGTAACAAGCTCTGTAAAGATGCAGTTTTGAATAAGAAACTTATGATGAAA
  CTACAAGAGTCAAAGTTTGATGTCATTCTGGCAGATGCCCTTAATCCCTGTGGTGAGCTA
  CTGGCTGAACTATTTAACATACCCTTTCTGTACAGTCTTCGATTCTCTGTTGGCTACACA
  TTTGAGAAGAATGGTGGAGGATTTCTGTTCCCTCCTTCCTATGTACCTGTTGTTATGTCA
  GAATTAAGTGATCAAATGATTTTCATGGAGAGGATAAAAAATATGATACATATGCTTTAT
  TTTGACTTTTGGTTTCAAATTTATGATCTGAAGAAGTGGGACCAGTTTTATAGTGAAGTT
  CTAGGAAGACCCACTACATTATTTGAGACAATGGGGAAAGCTGAAATGTGGCTCATTCGA
  ACCTATTGGGATTTTGAATTTCCTCGCCCATTCTTACCAAATGTTGATTTTGTTGGAGGA
  CTTCACTGTAAACCAGCCAAACCCCTGCCTAAGGAAATGGAAGAGTTTGTGCAGAGCTCT
  GGAGAAAATGGTATTGTGGTGTTTTCTCTGGGGTCGATGATCAGTAACATGTCAGAAGAA
  AGTGCCAACATGATTGCATCAGCCCTTGCCCAGATCCCACAAAAGGTTCTATGGAGATTT
  GATGGCAAGAAGCCAAATACTTTAGGTTCCAATACTCGACTGTAYAAGTGGTTACCCCAG
  AATGACCTTCTTGGTCATCCCAAAACCAAAGCTTTTATAACTCATGGTGGAACCAATGGC
  ATCTATGAGGCGATCTACCATGGGATCCCTATGGTGGGCATTCCCTTGTTTGCGGATCAA
  CATGATAACATTGCTCACATGAAAGCCAAGGGAGCAGCCCTCAGTGTGGACATCAGGACC
  ATGTCAAGTAGAGATTTGCTCAATGCATTGAAGTCAGTCATTAATGACCCTRTCTATAAA
  GAGAATRTCATGAAATTATCAAGAATTCATCATGACCAACCAATGAAGCCCCTGGATCGA
  GCAGTCTTCTGGATTGAGTTTGTCATGCGCCAYAAAGGAGCCAAGCACCTTCGAGTCGCA
  GCTCACAACCTCACCTGGATCCAGTACCACTCTTTGGATGTGATAGCATTCCTGCTGGCC
  TGCGTGGCAACTGTGATATTTATCATCACAAAATTTTGCCTGTTTTGTTTCCGAAAGCTT
  GCCAAAACAGGAAAGAAGAAGAAAAGAGATTAG
  
  Clone variation with respect to NM_001076.2
  253 t=>g;1065 c=>y;1312 g=>r;1327 g=>r;1413 c=>y;1568 a=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001076 unedited
  GCAAAGTCAGGATTTGTAATACGACTTCACTATAGNNGGCGGCCGCGCAATTCGGCACCA
  GNAAGCATTGCATAAGACCAGGATGTCTCTGAAAGGACGTCAGTCTTTCTGCTGATACAG
  CTCAGTTGTTACTTTAGCTCTGGAAGCTGTGGAAAGGTGCTAGTGTGGCCCACAGAATAC
  AGCCATTGGATAAATATGAAGACAATCCTGGAAGAGCTTGTTCAGAGGGGTCATGAGGTG
  ACTGTGTTGACATCTTCGGCTTCTACTCTTGTCAATGCCAGTAAATCATCTGCTATTAAA
  TTAGAAGTTTATCCTACATCTTTAACTAAAAATGATTTGGAAGATTCTCTTCTGAAAATT
  CTCGATAGATGGATATATGGTGTTTCAAAAAATACATTTTGGTCATATTTTTCACAATTA
  CAAGAATTGTGTTGGGAATATTATGACTACAGTAACAAGCTCTGTAAAGATGCAGTTTTG
  AATAAGAAACTTATGATGAAACTACAAGAGTCAAAGTTTGATGTCATTCTGGCAGATGCC
  CTTAATCCCTGTGGTGAGCTACTGGCTGAACTATTTAACATACCCTTTCTGTACAGTCTT
  CGATTCTCTGTTGGCTACACATTTGAGAAGAATGGTGGAGGATTTCTGTTCCCTCCTTCC
  TATGTACCTGTTGTTATGTCAGAATTAAGTGATCAAATGATTTTCATGGAGAGGATAAAA
  AATATGATACATATGCTTTATTTTGACTTTTGGGTTCAAATTTATGATCTGAAGGAGGGG
  GAACAGTTTTATAGATGAATTCTAGGAAGACCCCATAATTTATTTGAGACATTGGGGAAG
  CTAAATGGTGCTCATTCAACCTATTGGGATTTGAATTCCCTCGCCATTCTAACAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001076 unedited
  TCCGGGCCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCAGG
  AAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTAGGTT
  TTATATTATTTTTATTTTTCTTTTCTTTTTTTTTTATGGCTTGGATGACACTTTATTTTC
  AGATCCAATACTAGAAGTTGTTTCCATGTTCACATTTTCCTTCCTGGTTTAAAAAAAAGA
  GTTGTATTTTTTTTTTTTGCTTTTTTTAAATTATACTTTAAGTTTTAGGGTACATGTGCA
  CAACGTGCAGGTTAGCTACATATGTATACATGTGCCATGTTGGCGTGCTGCATCCAGTAA
  CTCGTCATTTAACATTAGGTATATCTCCAAATGCTATCCTTCCCCCCATTGTATTTTTCA
  TAGCTTAAAAATCATTGACATAGAATAATTCCAACTAAAGTACGTATTAAATCCCTGGAA
  AATAAATTTTGTCTTAACAAGGTAAGTTGTGAAAAGATGTTTTGTCACAGGAAAAAGGAA
  ATCCTCCATTTAAAACCCTCCATGCTGAAATAAAGGAGGAGTCCCATCTTTCAGTCATTC
  CACTTCAGGCTTTTGATATAACTAATNCTCTTTTCTTCTTCCTTCCCGTTTGGGCAAGCT
  TTCGGAACCAAACAGGGCAAAATTTGTGATGATAAATATCACAGTTGCCACGCAGCCAGC
  AGGATGCTATCAAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001076
• Insert Size: 2300 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001076.1, NP_001067.1
• RefSeq Size: 2090 bp
• RefSeq ORF: 1593 bp
• Locus ID: 7366
• Cytogenetics: 4q13.2
• Domains: UDPGT
• Protein Families: Transmembrane
• Protein Pathways: Androgen and estrogen metabolism, Ascorbate and aldarate metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pentose and glucuronate interconversions, Porphyrin and chlorophyll metabolism, Retinol metabolism, Starch and sucrose metabolism
• Gene Summary: 'This gene encodes a glycosyltransferase that is invovled in the metabolism and elimination of toxic compounts, both endogenous and of xenobiotic origin. This gene plays a role in the regulation of estrogens and androgens. This locus is present in a cluster of similar genes and pseudogenes on chromosome 4. [provided by RefSeq, Aug 2016]'