USP2 (NM_171997) Human Untagged Clone

CAT#: SC124133

USP2 (untagged)-Human ubiquitin specific peptidase 2 (USP2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: USP2
• Synonyms: UBP41; USP9
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_171997, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCGCACCTCGTACACCGTGACCCTGCCCGAGGACCCCCCCGCCGCCCCCTTTCCCGCCCTCGCCAAGG
  AGCTGCGGCCGCGCTCCCCTCTCTCCCCGTCCCTGCTGCTCTCCACCTTCGTGGGGCTCCTGCTCAACAA
  AGCCAAGAATTCTAAGAGTGCCCAGGGTCTGGCTGGTCTTCGAAACCTTGGGAACACGTGCTTCATGAAC
  TCAATTCTGCAGTGCCTGAGCAACACTCGGGAGTTGAGAGATTACTGCCTCCAGAGGCTCTACATGCGGG
  ACCTGCACCACGGCAGCAATGCACACACAGCCCTCGTGGAAGAGTTTGCAAAACTAATTCAGACCATATG
  GACTTCATCCCCCAATGATGTGGTGAGCCCATCTGAGTTCAAGACCCAGATCCAGAGATACGCACCGCGC
  TTTGTTGGCTATAATCAGCAGGATGCTCAGGAGTTCCTTCGCTTTCTTCTGGATGGGCTCCATAACGAGG
  TGAACCGAGTGACACTGAGACCTAAGTCCAACCCTGAGAACCTCGATCATCTTCCTGATGACGAGAAAGG
  CCGACAGATGTGGAGAAAATATCTAGAACGGGAAGACAGTAGGATCGGGGATCTCTTTGTTGGGCAGCTA
  AAGAGCTCGCTGACGTGTACAGATTGTGGTTACTGTTCTACGGTCTTCGACCCCTTCTGGGACCTCTCAC
  TGCCCATTGCTAAGCGAGGTTATCCTGAGGTGACATTAATGGACTGCATGAGGCTCTTCACCAAAGAGGA
  TGTGCTTGATGGAGATGAAAAGCCAACATGCTGTCGCTGCCGAGGCAGAAAACGGTGTATAAAGAAGTTC
  TCCATCCAGAGGTTCCCAAAGATCTTGGTGCTCCATCTGAAGCGGTTCTCAGAATCCAGGATCCGAACCA
  GCAAGCTCACAACATTTGTGAACTTCCCCCTAAGAGACCTGGACTTAAGAGAATTTGCCTCAGAAAACAC
  CAACCATGCTGTTTACAACCTGTACGCTGTGTCCAATCACTCCGGAACCACCATGGGTGGCCACTATACA
  GCCTACTGTCGCAGTCCAGGGACAGGAGAATGGCACACTTTCAACGACTCCAGCGTCACTCCCATGTCCT
  CCAGCCAAGTGCGCACCAGCGACGCCTACCTGCTCTTCTACGAACTGGCCAGCCCGCCCTCCCGAATGTA
  G
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_171997 unedited
  GGGGTCGGGTTTCGTGATCCGACTTCCTGTCGGCCGTGAGCATACCACTCTACCGNGCCG
  GGACCTTTTCTGTTGGCGGCGCACGCCGGGGAGGTTGAGGCGGAGGAGCGCGCGTTCGGG
  CGCCGCGGACGCTGTCCTGTAGCGGTCTCGCCGGCCTCGGCGTCCGGACTGTGGCACCGC
  GCGGGGACTCCCCCCGCGCCCCCGCTGCCAACGTTTTTCTCTTTGCCAAAGCCCGCCGCC
  CGTTCTGGGGGATGCGCACCTCGTTCTCCGTGACCCTGCCCGAGGACCCCCCCGCCGCCC
  CCTTTCCCGCCCTCGACAAGGAGCTGCGGCCGCGCTCCCCTCTCTCCCCGTCCCTGCTGC
  TCTCCACCTTCGTGGGGCTCCTGCTCAACAAAGCCAATAATTCTAAGAGTGCCCAGGGTC
  TGGCTGGTCTTCGAAACCTTGGGAACACGTGCTTCATGAACTCAATTCTGCAGTGCCTGA
  GCAACACTCGGGAGTTGAGAGATTACTGCCTTCAGACGCTCTACATGCGGGACCTGCACC
  ACGGCAGGCATGCACACACAGCCCTCGTGGGAAGAGTTTGCGAAACTAATTCAGACCATA
  TGGACTTCATCCCCCAATGATGTGGTGAGCCCATCTTGATTCAAGACCTAGATCCATAGA
  TATGCACCGCGCTTTGTTGGCTATTATCAGCCGGATGCTCACGAGTTTCTTCCCTTTCTC
  ACGGTATGGGCTCCATAACGATGTGAATCCGTTTGATCTTAGCCCTAGGTGCGGCCCTGA
  GAACCTTGTCCCCTTACTGCTGACCACCAAAGCCGACATAGGTTCAGAAAATTTTTTGCC
  CGAGAGAACCGTTGATCGGGGCTCCCTCTGGCGGGCACTTTATAACAGCCTGCCGGGTAA
  CAATGGGGGTACCGTT
  
• Restriction Sites: Please inquire
• ACCN: NM_171997
• ORF Size: 1191 bp
• Insert Size: 2700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_171997.1, NP_741994.1
• RefSeq Size: 1378
• RefSeq ORF: 1191
• Locus ID: 9099
• Protein Families: Protease
• Gene Summary: This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (2) is missing 2 exons from the 5' end, and contains an alternate 5' terminal exon compared to transcript variant 1. This results in a shorter isoform (b) with a different N-terminus compared to isoform a.