NALP12 (NLRP12) (NM_144687) Human Untagged Clone

CAT#: SC124283

NLRP12 (untagged)-Human NLR family, pyrin domain containing 12 (NLRP12), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NLRP12
• Synonyms: CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_144687 edited
  CCCCATGCTACGAACCGCAGGCAGGGACGGCCTCTGTCGCCTGTCCACCTACTTGGAAGA
  ACTCGAGGCTGTGGAACTGAAGAAGTTCAAGTTATACCTGGGGACCGCGACAGAGCTGGG
  AGAAGGCAAGATCCCCTGGGGAAGCATGGAGAAGGCCGGTCCCCTGGAAATGGCCCAGCT
  GCTCATCACCCACTTCGGGCCAGAGGAGGCCTGGAGGTTGGCTCTCAGCACCTTTGAGCG
  GATAAACAGGAAGGACCTGTGGGAGAGAGGACAGAGAGAGGACCTGGTGAGGGATACCCC
  ACCTGGTGGCCCGTCCTCACTTGGGAACCAGTCAACATGCCTTCTGGAAGTCTCTCTTGT
  CACTCCAAGAAAAGATCCCCAGGAAACCTACAGGGACTATGTCCGCAGGAAATTCCGGCT
  CATGGAAGACCGCAATGCGCGCCTAGGGGAATGTGTCAACCTCAGCCACCGGTACACCCG
  GCTCCTGCTGGTGAAGGAGCACTCAAACCCCATGCAGGTCCAGCAGCAGCTTCTGGACAC
  AGGCCGGGGACACGCGAGGACCGTGGGACACCAGGCTAGCCCCATCAAGATAGAGACCCT
  CTTTGAGCCAGACGAGGAGCGCCCCGAGCCACCGCGCACCGTGGTCATGCAAGGCGCGGC
  AGGGATAGGCAAGTCCATGCTGGCACACAAGGTGATGCTGGACTGGGCGGACGGGAAGCT
  CTTCCAAGGCAGATTTGATTATCTCTTCTACATCAACTGCAGGGAGATGAACCAGAGTGC
  CACGGAATGCAGCATGCAAGACCTCATCTTCAGCTGCTGGCCTGAGCCCAGCGCGCCTCT
  CCAGGAGCTCATCCGAGTTCCCGAGCGCCTCCTTTTCATCATCGACGGCTTCGATGAGCT
  CAAGCCTTCTTTCCACGATCCTCAGGGACCCTGGTGCCTCTGCTGGGAGGAGAAACGGCC
  CACGGAGCTGCTTCTTAACAGCTTAATTCGGAAGAAGCTGCTCCCTGAGCTATCTTTGCT
  CATCACCACACGGCCCACGGCTTTGGAGAAGCTCCACCGTCTGCTGGAGCACCCCAGGCA
  TGTGGAGATCCTGGGCTTCTCTGAGGCAGAAAGGAAGGAATACTTCTACAAGTATTTCCA
  CAATGCAGAGCAGGCGGGCCAAGTCTTCAATTACGTGAGGGACAACGAGCCTCTCTTCAC
  CATGTGCTTGGTCCCCCTGGTGTGCTGGGTGGTGTGTACCTGCCTCCAGCAGCAGCTGGA
  GGGTGGGGGGCTGTTGAGACAGACGTCCAGGACCACCACTGCAGTGTACATGCTCTACCT
  GCTGAGTCTGATGCAACCCAAGCCGGGGGCCCCGCGCCTCCAGCCCCCACCCAACCAGAG
  AGGGTTGTGCTCCTTGGCGGCAGATGGGCTCTGGAATCAGAAAATCCTATTTGAGGAGCA
  GGACCTCCGGAAGCACGGCCTAGACGGGGAAGACGTCTCTGCCTTCCTCAACATGAACAT
  CTTCCAGAAGGACATCAACTGTGAGAGGTACTACAGCTTCATCCACTTGAGTTTCCAGGA
  ATTCTTTGCAGCTATGTACTATATCCTGGACGAGGGGGAGGGCGGGGCAGGCCCAGACCA
  GGACGTGACCAGGCTGTTGACCGAGTACGCGTTTTCTGAAAGGAGCTTCCTGGCACTCAC
  CAGCCGCTTCCTGTTTGGACTCCTGAACGAGGAGACCAGGAGCCACCTGGAGAAGAGTCT
  CTGCTGGAAGGTCTCGCCGCACATCAAGATGGACCTGTTGCAGTGGATCCAAAGCAAAGC
  TCAGAGCGACGGCTCCACCCTGCAGCAGGGCTCCTTGGAGTTCTTCAGCTGCTTGTACGA
  GATCCAGGAGGAGGAGTTTATCCAGCAGGCCCTGAGCCACTTCCAGGTGATCGTGGTCAG
  CAACATTGCCTCCAAGATGGAGCACATGGTCTCCTCGTTCTGTCTGAAGCGCTGCAGGAG
  CGCCCAGGTGCTGCACTTGTATGGCGCCACCTACAGCGCGGACGGGGAAGACCGCGCGAG
  GTGCTCCGCAGGAGCGCACACGCTGTTGGTGCAGCTACCAGAGAGGACCGTTCTGCTGGA
  CGCCTACAGTGAACATCTGGCAGCGGCCCTGTGCACCAATCCAAACCTGATAGAGCTGTC
  TCTGTACCGAAATGCCCTGGGCAGCCGGGGGGTGAAGCTGCTCTGTCAAGGACTCAGACA
  CCCCAACTGCAAACTTCAGAACCTGAGGCTGAAGAGGTGCCGCATCTCCAGCTCAGCCTG
  CGAGGACCTCTCTGCAGCTCTCATAGCCAATAAGAATTTGACAAGGATGGATCTCAGTGG
  CAACGGCGTTGGATTCCCAGGCATGATGCTGCTTTGCGAGGGCCTGCGGCATCCCCAATG
  CAGGCTGCAGATGATTCAGTTGAGGAAGTGTCAGCTGGAGTCCGGGGCTTGTCAGGAGAT
  GGCTTCTGTGCTCGGCACCAACCCACATCTGGTTGAGTTGGACCTGACAGGAAATGCACT
  GGAGGATTTGGGCCTGAGGTTACTATGCCAGGGACTGAGGCACCCAGTCTGCAGACTACG
  GACTTTGTGGCTGAAGATCTGCCGCCTCACTGCTGCTGCCTGTGACGAGCTGGCCTCAAC
  TCTCAGTGTGAACCAGAGCCTGAGAGAGCTGGACCTGAGCCTGAATGAGCTGGGGGACCT
  CGGGGTGCTGCTGCTGTGTGAGGGCCTCAGGCATCCCACGTGCAAGCTCCAGACCCTGCG
  GCTGGATAGCTGTGGCCTCACAGCCAAGGCTTGTGAGAATCTTTACTTCACCCTGGGGAT
  CAACCAGACCTTGACCGACCTTTACCTGACCAACAACGCCCTAGGGGACACAGGTGTCCG
  ACTGCTTTGCAAGCGGCTGAGCCATCCTGGCTGCAAACTCCGAGTCCTCTGGTTATTTGG
  GATGGACCTGAATAAAATGACCCACAGTAGGTTGGCAGCGCTTCGAGTAACAAAACCTTA
  TTTGGACATTGGCTGCTGAATGGTCCTATCTGCTGGCTCTCCCCTGAGATCTGGACAGAG
  GAAGATGGGAGGGTGCTCATCACCCCCCCAGCATAATGATCAGCCTCCTTCCTAGAGACA
  GACTCATGCAGATTGAGATCAAAAGTCCCTCTGCTTGGGATCAAATTAATGTTTGACAGA
  GCTGGCCAGGCGTGGTGGCTCATGTATGTAATCCTAGCACTTCGAGAGGCCGAGGCAGGT
  GGATCACGAGGTCAGGAGTTTGAGATTAGCCTGGCCAAGATGGTGAAACCCTGTCTCTAC
  TAAAAATAAAAAAAAATTAGCCAGG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_144687 unedited
  NGGCAAGTCAAAATTTGTATACGACTCCTATAGGCGGCCGCNGATTCGGCACCAGCCCCA
  TGCTACGAACCGCAGGCAGGGACGGCCTCTGTCGCCTGTCCACCTACTTGGAAGAACTCG
  AGGCTGTGGAACTGAAGAAGTTCAAGTTATACCTGGGGACCGCGACAGAGCTGGGAGAAG
  GCAAGATCCCCTGGGGAAGCATGGAGAAGGCCGGTCCCCTGGAAATGGCCCAGCTGCTCA
  TCACCCACTTCGGGCCAGAGGAGGCCTGGAGGTTGGCTCTCAGCACCTTTGAGCGGATAA
  ACAGGAAGGACCTGTGGGAGAGAGGACAGAGAGAGGACCTGGTGAGGGATACCCCACCTG
  GTGGCCCGTCCTCACTTGGGAACCAGTCAACATGCCTTCTGGAAGTCTCTCTTGTCACTC
  CAAGAAAAGATCCCCAGGAAACCTACAGGGACTATGTCCGCAGGAAATTCCGGCTCATGG
  AAGACCGCAATGCGCGCCTAGGGGAATGTGTCAACCTCAGCCACCGGTACACCCGGCTCC
  TGCTGGTGAAGGAGCACTCAAACCCCATGCAGGTCCAGCAGCAGCTTCTGGACACAGGCC
  GGGGACACGCGAGGACCGTGGGACACCAGGCTAGCCCCATCAAGATAGAGACCCTCTTTG
  AGCCAGACGAGGAGCGCCCCGAGCCACCGCGCACCGTGGTCATGCAAGGCGCGGCAGGGA
  TAGGCAAGTCCATGCTGGCACACAANGTGATGNCTGACTGGGGCGACGGGAAGCTCTTCC
  AGGCAGATTTGATTATTCTCTCTACATCAACTGCAGGGAGATGAACCAGAGTGCCACGGA
  ATGCAGCATGNCAGACCTCATCTTCAGCTGCTGGCCTGAGCCCACGCGCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_144687 unedited
  CCCTCGTGGAGTGATGTTCTTCTTTCTTAGTAAANACAGGGTTTCACCATCTTGTGCCAG
  CTAATCTCAAACTCCTGACCTCGTGATCCACCTGCCTCGGCCTCTCGAAGTGCTAGGATT
  ACATACATGAGCCACCACGCCTGGCCAGCTCTGTCAAACATTAATTTGATCCCAAGCAGA
  GGGACTTTTGATCTCAATCTGCATGAGTCAGTCTCTAGGAAGGAGGCTGATCATTATGCT
  GGGGGGGTGATGAGCACCCTCCCATCTTCCTCTGTCCAGATCTCAGGGGAGAGCCAGCAG
  ATAGGACCATTCAGCAGCCAATGTCCAAATAAGGTTTTGTTACTCGAAGCGCTGCCAACC
  TACTGTGGGTCATTTTATTCAGGTCCATCCCAAATAACCAGAGGACTCGGAGTTTGCAGC
  CAGGATGGCTCAACCGCTTGCAAAGCAGTCGGACACCTGTGTCCCCTAGGGCGTTGTTGG
  TCAGGTAAAGGTCCGACAAGGTCTGGTTGGTCCCCAGGGTGAAGTAAAGATTCTCACAAG
  CCTTGGCTGTGAGGGCACAGCTTTCCAGCCCTAGGGTCTGGACCTTGCACCGTGGGATGC
  CCTGAGCCCTCACACAGCAGCAGCGCCCCAGAGGTTCCCCCAAATCAATCAAGGCTCAGG
  TCCCGCTCTCTTTAGGCTCTGGTTCACCCTTGTGAGTTTGAGTGCCCGACCGGTTCCAAG
  CGAGCAGGCAGTGAGGCTGCCTCCCTTCCTCCCCAAAAGTCTCCCTGTGTGGAGACCCGA
  GTGCCCTATATTCCCCGGTACTAGAAACCCGCAGGAGCCAATTACTTCAGTGATATTATC
  TGTGAGGGGCACCTAAACCACATAGTGGTTGGACGCCTCACACATAACCCTACTACCTAG
  ATGGACCGTTCTATAAATGTACCTTGTCCCAGAGAGATATCATCGCACCCACACATGCGT
  AATGGCTTGAAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_144687
• ORF Size: 3186 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_144687.1, NP_653288.1
• RefSeq Size: 3827
• RefSeq ORF: 3186
• Locus ID: 91662
• Domains: LRR, PAAD_DAPIN
• Gene Summary: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
  Transcript Variant: This variant (2) uses an alternate splice site in the central coding region, compared to variant 3, resulting in an isoform (2) that is 1 aa shorter than isoform 3.