PMP22 (NM_153322) Human Untagged Clone

CAT#: SC124315

PMP22 (untagged)-Human peripheral myelin protein 22 (PMP22), transcript variant 3


  "NM_153322" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PMP22
Synonyms CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC124315 sequence for NM_153322 edited (data generated by NextGen Sequencing)
ATGCTCCTCCTGTTGCTGAGTATCATCGTCCTCCACGTCGCGGTGCTGGTGCTGCTGTTC
GTCTCCACGATCGTCAGCCAATGGATCGTGGGCAATGGACACGCAACTGATCTCTGGCAG
AACTGTAGCACCTCTTCCTCAGGAAATGTCCACCACTGTTTCTCATCATCACCAAACGAA
TGGCTGCAGTCTGTCCAGGCCACCATGATCCTGTCGATCATCTTCAGCATTCTGTCTCTG
TTCCTGTTCTTCTGCCAACTCTTCACCCTCACCAAGGGGGGCAGGTTTTACATCACTGGA
ATCTTCCAAATTCTTGCTGGTCTGTGCGTGATGAGTGCTGCGGCCATCTACACGGTGAGG
CACCCGGAGTGGCATCTCAACTCGGATTACTCCTACGGTTTCGCCTACATCCTGGCCTGG
GTGGCCTTCCCCCTGGCCCTTCTCAGCGGTGTCATCTATGTGATCTTGCGGAAACGCGAA
TGA

Clone variation with respect to NM_153322.1
>OriGene 5' read for NM_153322 unedited
CGACTTTCTTAGGGCGGCCGCGAATTCGGCACGAGGGGAACATCTCGGGGAGCCTGGTTG
GAAGCTGCAGGCTTAGTCTGTCGGCTGCGGGTCTCTGACTGCCCTGTGGGGAGGGTCTTG
CCTTAACATCCCTTGCATTTGGCTGCAAAGAAATCTGCTTGGAAGAAGGGGTTACGCTGT
TTGGCCGGGCAGAAACTCCGCTGAGCAGAACTTGCCGCCAGAATGCTCCTCCTGTTGCTG
AGTATCATCGTCCTCCACGTCGCGGTGCTGGTGCTGCTGTTCGTCTCCACGATCGTCAGC
CAATGGATCGTGGGCAATGGACACGCAACTGATCTCTGGCAGAACTGTAGCACCTCTTCC
TCAGGAAATGTCCACCACTGTTTCTCATCATCACCAAACGAATGGCTGCAGTCTGTCCAG
GCCACCATGATCCTGTCGATCATCTTCAGCATTCTGTCTCTGTTCCTGTTCTTCTGCCAA
CTCTTCACCCTCACCAAGGGGNGGCAGGTTTTACATCACTGGAATCTTCCAAATTCTTGC
TGGTCTGTGCGTGATGAGTGCTGCGGCCATCTACACGGTGAGGCACNCCGGAGTGGCATC
TCAACTCGGATTACTCCTACGGTTTCGCCTACATCCTGGCCTAGGGTGGCCTTCCCCCTG
GCCCTTCTCAGCGTGTCATCTATGTGATCTTGCGGAAACGCGAATGAGCCCCAGACGGTC
TGTCTGAGCTCTGAGCGCTAATGGGGAAGGNNGGGGAGGGGGAACCNNANNGCGCCAAGA
ATAAGAGCTAGCCCATATCCCAACTCAACCAACCAACAGAAGAGGGGGGGGGGGGGGCCC
CCTTCCCTTTAAACCCTTTTCTCTCGCCCCGTGCGCGCCTTGGTGCCTCGCCCCTGCGGC
CCCACCCGCGCCCCACTCCTCCCCCTATCTTTCTTCTAGCATCCCCCCCCCTCCTTCCTC
TCTCCTCATTCCCCCCTCTA
Restriction Sites NotI-NotI     
ACCN NM_153322
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_153322.1, NP_696997.1
RefSeq Size 1669 bp
RefSeq ORF 483 bp
Locus ID 5376
Cytogenetics 17p12
Protein Families Transmembrane
Gene Summary 'This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]'
Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-5 encode the same isoform (1).

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