DEGS1 (NM_144780) Human Untagged Clone

CAT#: SC124544

DEGS1 (untagged)-Human degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) (DEGS1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DEGS1
• Synonyms: DEGS; Des-1; DES1; FADS7; MGC5079; MIG15; MLD
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_144780, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGAGCCGCGTCTCGCGGGAAGACTTCGAGTGGGTCTACACCGACCAGCCGCACGCCGACCGGCGCC
  GGGAGATCCTGGCAAAGTATCCAGAGATAAAGTCCTTGATGAAACCTGATCCCAATTTGATATGGATTAT
  AATTATGATGGTTCTCACCCAGTTGGGTGCATTTTACATAGTAAAAGACTTGGACTGGAAATGGGTCATA
  TTTGGGGCCTATGCGTTTGGCAGTTGCATTAACCACTCAATGACTCTGGCTATTCATGAGATTGCCCACA
  ATGCTGCCTTTGGCAACTGCAAAGCAATGTGGAATCGCTGGTTTGGAATGTTTGCTAATCTTCCTATTGG
  GATTCCATATTCAATTTCCTTTAAGAGGTATCACATGGATCATCATCGGTACCTTGGAGCTGATGGCGTC
  GATGTAGATATTCCTACCGATTTTGAGGGCTGGTTCTTCTGTACCGCTTTCAGAAAGTTTATATGGGTTA
  TTCTTCAGCCTCTCTTTTATGCCTTTCGACCTCTGTTCATCAACCCCAAACCAATTACGTATCTGGAAGT
  TATCAATACCGTGGCACAGGTCACTTTTGACATTTTAATTTATTACTTTTTGGGAATTAAATCCTTAGTC
  TACATGTTGGCAGCATCTTTACTTGGCCTGGGTTTGCACCCAATTTCTGGACATTTTATAGCTGAGCATT
  ACATGTTCTTAAAGGGTCATGAAACTTACTCATATTATGGGCCTCTGAATTTACTTACCTTCAATGTGGG
  TTATCATAATGAACATCATGATTTCCCCAACATTCCTGGAAAAAGTCTTCCACTGGTGAGGAAAATAGCA
  GCTGAATACTATGACAACCTCCCTCACTACAATTCCTGGATAAAAGTACTGTATGATTTTGTGATGGATG
  ATACAATAAGTCCCTACTCAAGAATGAAGAGGCACCAAAAAGGAGAGATGGTGCTGGAGTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_144780 unedited
  GGGGTTCAAATTTGTATACGACTCATATAGGCGGCCGCGAAATTCGCACGAGGCGCCGCC
  GCCGCCACCTCTGAGCAGCCGGCTGGGAGCGAGAGCCGACAGCTAGTCTGCAAGCCACCG
  CTGTCGCCATGGGGAGCCGCGTCTCGCGGGAAGACTTCGAGTGGGTCTACACCGACCAGC
  CGCACGCCGACCGGCGCCGGGAGATCCTGGCAAAGTATCCAGAGATAAAGTCCTTGATGA
  AACCTGATCCCAATTTGATATGGATTATAATTATGATGGTTCTCACCCAGTTGGGTGCAT
  TTTACATAGTAAAAGACTTGGACTGGAAATGGGTCATATTTGGGGCCTATGCGTTTGGCA
  GTTGCATTAACCACTCAATGACTCTGGCTATTCATGAGATTGCCCACAATGCTGCCTTTG
  GCAACTGCAAAGCAATGTGGAATCGCTGGTTTGGAATGTTTGCTAATCTTCCTATTGGGA
  TTCCATATTCAATTTCCTTTAAGAGGTATCACATGGATCATCATCGGTACTTTGGAGCTG
  ATGGCGTCGATGTAGATATTCCTACCGATTTTGAGGGCTGGTTCTTCTGTACCGCTTTCA
  GAAAGTTTATATGGGTTATTCTTCAGCCTCTCTTTTATGCCTTTCGACCTCTGTTCATCA
  ACCCCAAACCAATTACGTATCTGGAAGTTATCAATACCGTGGCACAGGTCACTTTTGACA
  TTNTAATTTATTACTTTNTGGGGATTAAATCCTTAGTCTACATNGTGGCAGCATCTTTAC
  TTGGCCTGNGTTTGCACCCAATTTCTGGACATTTTATAGCTGAGCATTACATGTNCTTAA
  AGGGTCATGAAACTTACTCATATTATGGGCCTCTGAAATTACTTACCTTCAATGTGGGNT
  ATCATNATGAACATCATA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_144780 unedited
  GACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTGAAGGGGGGAAATTCAGTAAGTACTTTATTTATGAGTAAGGCTGTACAGGATTCAGCA
  GTGTCTAATTCGGGTCCCATATAGAAGTTAAAATTTTTAAATGAGTAATTCAGCTTACAG
  GGAAATATATTTTCATCTCAATCTTTTATGCTATATCATACCTCAGGCTTTTTAAAAATT
  ATTTTTGAGATGAAATTTTAAAGTTCCCCCGGTACCCAAGTTACCATATTATATAGTATA
  AAGATAGGGAAATACAAAAATGTAACAAATACTAATACACTGGGATTAATAGCTGGTTAT
  TAGCTTTTTAATAAAGCAAAACTTTATAGGGAAATAAACTAAAAATAGCTTTTTATTTTT
  TATATATATTTATTTATTTTTGAGAAGGGGTCTTGCTCTGTTGCCCAGGGTGGAGTGCAG
  TGGCACAATCTTGGGTCACTGCAGCCTCTGCCTCCGCCTCCTGGGTTCAAGCAATTCTCC
  CACCTCAGCCTCCCATGTAGCTGGGATTACAGGCATGTGCCGCCACGCCCGGCTAATTTT
  TGCATTTTTAGTAAAGATGGGGTTACACCGTGTTGGCCAGGCTGGTCTCGAACTCCTGAC
  CTCAGGTGATCCACCCACCTTGGCCTCCCAAAGTGCTGGGATTATAGGCATGAGCCACCG
  TGCCTGGCGAAATAGCTTTTTAGAAGCTTNTTAATGATATGCTTATAAATGACAGACATG
  AGTGAAACACCTCAATGACGATATACACCAGTCACAAGTTCCCTGTGAGTGAACTGAGCG
  TACAGAGTCAGCTGACTGTTAAAAGCAGATCACTTTTTGTATAACGACCTTTATCTGAAA
  TGTGCAGGGAGCTCTGACCTCACTGCCTCAAGTTATATGCAAAATCCATTTATATCTAGG
  TTGGAGAAAATNTTTGACCTAAGT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_144780
• ORF Size: 972 bp
• Insert Size: 5700
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_144780.1, NP_659004.1
• RefSeq Size: 1681
• RefSeq ORF: 972
• Locus ID: 8560
• Domains: FA_desaturase
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism
• Gene Summary: This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010]
  Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants encode the same isoform.