DEGS1 (NM_144780) Human Untagged Clone

CAT#: SC324251

DEGS1 (untagged)-Human degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) (DEGS1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DEGS1
• Synonyms: DEGS; Des-1; DES1; FADS7; MGC5079; MIG15; MLD
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_144780.1 CACAGCCGGCCGACACCACACCAGCCGGGGAGCCGCCGCCGCCGCCGCCACCTCTGAGCA
  GCCGGCTGGGAGCGAGAGCCGACAGCTAGTCTGCAAGCCACCGCTGTCGCCATGGGGAGC
  CGCGTCTCGCGGGAAGACTTCGAGTGGGTCTACACCGACCAGCCGCACGCCGACCGGCGC
  CGGGAGATCCTGGCAAAGTATCCAGAGATAAAGTCCTTGATGAAACCTGATCCCAATTTG
  ATATGGATTATAATTATGATGGTTCTCACCCAGTTGGGTGCATTTTACATAGTAAAAGAC
  TTGGACTGGAAATGGGTCATATTTGGGGCCTATGCGTTTGGCAGTTGCATTAACCACTCA
  ATGACTCTGGCTATTCATGAGATTGCCCACAATGCTGCCTTTGGCAACTGCAAAGCAATG
  TGGAATCGCTGGTTTGGAATGTTTGCTAATCTTCCTATTGGGATTCCATATTCAATTTCC
  TTTAAGAGGTATCACATGGATCATCATCGGTACCTTGGAGCTGATGGCGTCGATGTAGAT
  ATTCCTACCGATTTTGAGGGCTGGTTCTTCTGTACCGCTTTCAGAAAGTTTATATGGGTT
  ATTCTTCAGCCTCTCTTTTATGCCTTTCGACCTCTGTTCATCAACCCCAAACCAATTACG
  TATCTGGAAGTTATCAATACCGTGGCACAGGTCACTTTTGACATTTTAATTTATTACTTT
  TTGGGAATTAAATCCTTAGTCTACATGTTGGCAGCATCTTTACTTGGCCTGGGTTTGCAC
  CCAATTTCTGGACATTTTATAGCTGAGCATTACATGTTCTTAAAGGGTCATGAAACTTAC
  TCATATTATGGGCCTCTGAATTTACTTACCTTCAATGTGGGTTATCATAATGAACATCAT
  GATTTCCCCAACATTCCTGGAAAAAGTCTTCCACTGGTGAGGAAAATAGCAGCTGAATAC
  TATGACAACCTCCCTCACTACAATTCCTGGATAAAAGTACTGTATGATTTTGTGATGGAT
  GATACAATAAGTCCCTACTCAAGAATGAAGAGGCACCAAAAAGGAGAGATGGTGCTGGAG
  TAAATATCATTAGTGCCAAAGGGATTCTTCTCCAAAACTTTAGATGATAAAATGGAATTT
  TTGCATTATTAAACTTGAGACCAGTGATGCTCAGAAGCTCCCCTGGCACAATTTCAGAGT
  AAGAGCTCGGTGATACCAAGAAGTGAATCTGGCTTTTAAACAGTCAGCCTGACTCTGTAC
  TGCTCAGTTTCACTCACAGGAAACTTGTGACTTGTGTATTATCGTCATTGAGGATGTTTC
  ACTCATGTCTGTCATTTTATAAGCATATCATTTAAAAAGCTTCTAAAAAGCTATTTCGCC
  AGGCACGGTGGCTCATGCCTATAATCCCAGCACTTTGGGAGGCCAAGGTGGGTGGATCAC
  CTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACACGGTGAAACCCCATCTCTACTAAAA
  ATGCAAAAATTAGCCGGGCGTGGCGGCACATGCCTGTAATCCCAGCTACATGGGAGGCTG
  AGGTGGGAGAATTGCTTGAACCCAGGAGGCGGAGGCAGAGGCTGCAGTGACCCAAGATTG
  TGCCACTGCACTCCACCCTGGGCAACAGAGCAAGACCCCATCTCAAAAATAAATAAATAT
  ATATAAAAAATAAAAAGCTATTTCTAGTTTATTTCACTATAAAGTTTTGCTTTATTAAAA
  AGCTAATAAACAGCTATTAATCACAGTGTATTAGTATTTGTTACATTTTTGTATTTCACT
  ATCTTTATACTATATAATATGGTTACTTGGGTACCGGGGGAACTTTAAAATTTCATCTCA
  AAAATAATTTTTAAAAAGCCTGAGGTATGATATAGCATAAAAGATTGAGATGAAAATATA
  TTTCCCTGTAAGCTGAATTACTCATTTAAAAATTTTAACTTCTATATGGGACCCGAATTA
  GACACTGCTGAATCCTGTACAGCCTTACTCATAAATAAAGTACTTACTGAATTTCCACCA
  TTCAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_144780.1 unedited
  TGCCTAGCCTGCAAGCCTCCCGCTGTTTTGACCTCCATAGAAGACACCGGGACCGATCCA
  GCCTCCGGACTCTAGCCTAGGCCGCGGGACGGATAACAATTTCACACAGGAAACAGCTAT
  GACCATTAGGCCTATTTAGGTGACACTATAGAACAAGTTTGTACAAAAAAGCAGGCTGGT
  ACCGGTCCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGCACAGCCGGCCGACACCA
  CACCAGCCGGGGAGCCGCCGCCGCCGCCGCCACCTCTGAGCAGCCGGCTGGGAGCGAGAG
  CCGACAGCTAGTCTGCAAGCCACCGCTGTCGCCATGGGGAGCCGCGTCTCGCGGGAAGAC
  TTCGAGTGGGTCTACACCGACCAGCCGCACGCCGACCGGCGCCGGGAGATCCTGGCAAAG
  TATCCAGAGATAAAGTCCTTGATGAAACCTGATCCCAATTTGATATGGATTATAATTATG
  ATGGTTCTCACCCAGTTGGGTGCATTTTACATAGTAAAAGACTTGGACTGGAAATGGGTC
  ATATTTGGGGCCTATGCGTTTGGCAGTTGCATTAACCACTCAATGACTCTGGCTATTCAT
  GAGATTGCCCACAATGCTGCCTTTGGCAACTGCAAAGCAATGTGGAATCGCTGGTTTGGA
  ATGTTTGCTAATCTTCCTATTGGGATTCCATATTCAATTTCCTTTAAGAGGTATCACATG
  GATCATCATCGGTACCTTGAGCTGATGGCGTCGATGTAGATATTCCTACCGATTTTGAGG
  GCTGGTTCTTCTGTACCGCTTTCAGAAGTTTAATATGGGTTATTCTCAGCCTCTCTTTTA
  TGCCTTTCGACCTCTGTTCATCACCCCAAACCATTACGTATCTGAGTTATCATACGTGCC
  ACAGTCACTTTGACATTTAATTTATTAACTTTTGGAATAAAATCCTTAGTCTAC
• Restriction Sites: Please inquire
• ACCN: NM_144780
• ORF Size: 972 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_144780.1, NP_659004.1
• RefSeq Size: 1681
• RefSeq ORF: 972
• Locus ID: 8560
• Domains: FA_desaturase
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism
• Gene Summary: This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010]
  Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants encode the same isoform.