ketohexokinase (KHK) (NM_006488) Human Untagged Clone

CAT#: SC124910

KHK (untagged)-Human ketohexokinase (fructokinase) (KHK), transcript variant b


  "NM_006488" in other vectors (4)

Reconstitution Protocol

USD 660.00

In Stock*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol KHK
Synonyms ketohexokinase; ketohexokinase (fructokinase)
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC124910 sequence for NM_006488 edited (data generated by NextGen Sequencing)
ATGGAAGAGAAGCAGATCCTGTGCGTGGGGCTAGTGGTGCTGGACGTCATCAGCCTGGTG
GACAAGTACCCTAAGGAGGACTCGGAGATAAGGTGTTTGTCCCAGAGATGGCAGCGCGGA
GGCAACGCGTCCAACTCCTGCACCATTCTCTCCCTGCTCGGAGCCCCCTGTGCCTTCATG
GGCTCAATGGCTCCTGGCCATGTTGCTGACTTCCTGGTGGCCGACTTCAGGCGGCGGGGC
GTGGACGTGTCTCAGGTGGCCTGGCAGAGCAAGGGGGACACCCCCAGCTCCTGCTGCATC
ATCAACAACTCCAATGGCAACCGTACCATTGTGCTCCATGACACGAGCCTGCCAGATGTG
TCTGCTACAGACTTTGAGAAGGTTGATCTGACCCAGTTCAAGTGGATCCACATTGAGGGC
CGGAACGCATCGGAGCAGGTGAAGATGCTGCAGCGGATAGACGCACACAACACCAGGCAG
CCTCCAGAGCAGAAGATCCGGGTGTCCGTGGAGGTGGAGAAGCCACGAGAGGAGCTCTTC
CAGCTGTTTGGCTACGGAGACGTGGTGTTTGTCAGCAAAGATGTGGCCAAGCACTTGGGG
TTCCAGTCAGCAGAGGAAGCCTTGAGGGGCTTGTATGGTCGTGTGAGGAAAGGGGCTGTG
CTTGTCTGTGCCTGGGCTGAGGAGGGCGCCGACGCCCTGGGCCCTGATGGCAAATTGCTC
CACTCGGATGCTTTCCCGCCACCCCGCGTGGTGGATACACTGGGAGCTGGAGACACCTTC
AATGCCTCCGTCATCTTCAGCCTCTCCCAGGGGAGGAGCGTGCAGGAAGCACTGAGATTC
GGGTGCCAGGTGGCCGGCAAGAAGTGTGGCCTGCAGGGCTTTGATGGCATCGTGTGA

Clone variation with respect to NM_006488.2
145 g=>a
>OriGene 5' read for NM_006488 unedited
AGCATTTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGGCTCTGGGN
NAGTAGCCTCATGGNAAGAGAAGCAGATCCTGTGCGTGGGGCTAGTGGTGCTGGACGTCA
TCAGCCTGGTGGACAAGTACCCTAAGGAGGACTCGGAGATAAGGTGTTTGTCCCAGAGAT
GGCAGCGCGGAGGCAACGCGTCCAACTCCTGCACCATTCTCTCCCTGCTCGGAGCCCCCT
GTGCCTTCATGGGCTCAATGGCTCCTGGCCATGTTGCTGACTTCCTGGTGGCCGACTTCA
GGCGGCGGGGCGTGGACGTGTCTCAGGTGGCCTGGCAGAGCAAGGGGGACACCCCCAGCT
CCTGCTGCATCATCAACAACTCCAATGGCAACCGTACCATTGTGCTCCATGACACGAGCC
TGCCAGATGTGTCTGCTACAGACTTTGAGAAGGTTGATCTGACCCAGTTCAAGTGGATCC
ACATTGAGGGCCGGAACGCATCGGAGCAGGTGAAGATGCTGCAGCGGATAGACGCACACA
ACACCAGGCAGCCTCCAGAGCAGAAGATCCGGGTGTCCGTGGAGGTGGAGAAGCCACGAG
AGGAGCTCTTCCAGCTGTTTGGCTACGGAGACGTGGTGTTTGTCAGCAAAGATGTGGCCA
AGCACTTGGGGTTCCAGTCAGCAGAGGAAGCCTTGAGGGGCTTGTATGGTCGTGTGAGGA
AAGGGGCTGTGCTTGTCTGTGCCTGGGCTGAGAGGGCGCCGACGCCCTGNGCCCCTGATG
GCAATTGCTCCACTCGGATGCTTTTCCGCCACCCCGCGTGGTGGATACACTGGGAGCTGG
AGACACCTTCATGCCTNCGTCATCTTCAGCCTCTCCCAGGGGGAGAGCGTGCAGAAGCAC
TGAGATTCGGTGCCCAGTGCCCGCAGAAATGTGGCTGCAGGCTTGATGCATCTGTGAAAC
AGTGCCGCTCTACAACATGGAACACATGGGCTGCTGGCTTTCCTC
>OriGene 3' read for NM_006488 unedited
TATGGACGCGGCCGCATTCTANAGTCGGTTTTTTTTTTTTTTTTTTTGGCTCTGAGGAAG
ATTATTTGCTCTGAGGCTCTGCATCCCCCAGCCATCCCCCCAAAGCCTCTCCCTGTGGGG
AACACAGGACACAGGCAGAGTCCTCCCCACAGCTTGCATCTGTCCCCTGAACAGGGCAAC
CTGGACGCCAGGCTGGATGGAGGGGAGAAGGCGATGCAGCCGCAATGGTAGTCTCCATGG
TGTGTGAGGAGCCGGCACCTGCTCTCACACGATGCCATCAAAGCCCTGCAGGCCACACTT
CTTGCCGGCCACCTGGCACCCGAATCTCAGTGCTTCCTGCACGCTCCTCCCCTGGGAGAG
GCTGAAGATGACGGAGGCATTGAAGGTGTCTCCAGCTCCCAGTGTATCCACCACGCGGGG
TGGCGGGAAAGCATCCGAGTGGAGCAATTTGCCATCAGGGCCCAGGGCGTCGGCGCCCTC
CTCAGCCCAGGCACAGACAAGCACAGCCCCTTTCCTCACACGACCATACAAGCCCCTCAA
GGCTTCCTCTGCTGACTGGAACCCCAAGTGCTTGGCCACATCTTTGCTGACAAACACCAC
GTCTCCGTAGCCAAACAGCTGGAAGAGCTCCTCTCGTGGCTTCTCCACCTCCACGGACAC
CCGGATCTTCTGCTCTGGAGGCTGCCTGGTGTTGTGTGCGTCTATCCGCTGCAGCATCTT
CACCTGCTCCGATGCGTTCCGGCCCTCAATGTGGATCCACTTGAACTGGGTCAGATCAAC
CTTCTCAAAGTCTGTAGCAGACACATCTGGCAGGCTCGTGTCATGGAGCACAATGGTACG
GTTGCCATTGGAGTTGTTGATGATGCANCANGAGCTGGGGGGTGTCCCCCTTGCTCTGCC
NAGGCCACCTGAGAACGTNCACGCCCCGCCGCNNCTGAGTCGNCACCAGNAAAGTCAGCA
CATGGCCCAGGAGCCATTGAG
Restriction Sites NotI-NotI     
ACCN NM_006488
Insert Size 1000 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_006488.1, NP_006479.1
RefSeq Size 1899 bp
RefSeq ORF 897 bp
Locus ID 3795
Cytogenetics 2p23.3
Domains pfkB
Protein Families Druggable Genome
Protein Pathways Fructose and mannose metabolism, Metabolic pathways
Gene Summary 'This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant utilizes the alternate exon 3c and encodes isoform b, which exhibits higher enzymatic activity than isoform a.

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.