CENTD1 (ARAP2) (NM_015230) Human Untagged Clone

CAT#: SC125455

ARAP2 (untagged)-Human ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 (ARAP2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARAP2
• Synonyms: CENTD1; PARX
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_015230 edited
  ATGTCCTCAGTCAGTGAAGTAAATGTGGATATAAAAGATTTCCTAATGAGCATTAATTTG
  GAGCAGTATCTCTTACATTTCCATGAGTCTGGTTTTACTACTGTGAAGGACTGTGCAGCA
  ATAAATGACAGCCTGCTGCAGAAAATTGGAATATCACCTACAGGTCACCGTAGGAGGATA
  CTTAAACAGTTACAGATAATCTTGTCAAAAATGCAAGATATTCCAATATATGCAAATGTT
  CATAAAACTAAGAAGAATGATGACCCTTCAAAGGATTACCATGTTCCATCTTCTGATCAG
  AATATCTGCATAGAACTTTCCAATTCTGGTAGTGTTCAGACATCTAGCCCACCGCAGTTG
  GAGACTGTTAGAAAAAATCTTGAAGACAGTGATGCAAGTGTGGAAAGAAGCCAGTATCCT
  CAATCAGATGATAAGCTGTCTCCTCCTAAACGCGACTTCCCCACTGCAGAGGAACCACAC
  CTGAATTTGGGTTCTTTGAATGATTCTTTATTTGGTAGTGACAATATTAAAATAGAATCA
  TTGATTACAAAGAAGACTGTGGATCACACAGTTGAAGAACAACAAACAGAAAAAGTTAAA
  TTGATCACAGAAAATCTCAGTAAGCTCCCTAATGCAGACTCTGAATGCCTTTCTTTTGTT
  GGCTGTTCAACATCAGGAACAAATTCTGGAAATGGAACAAATGGTTTATTAGAAGGATCA
  CCACCATCCCCATTCTTTAAGTTTCAAGGAGAAATGATTGTAAATGACTTGTATGTTCCA
  TCATCACCAATCCTAGCACCTGTGAGAAGTCGTAGCAAGTTGGTTTCAAGACCATCTCGA
  TCTTTTCTGCTAAGACATCGACCTGTACCAGAGATTCCAGGGTCAACAAAAGGAGTTTCT
  GGGAGCTATTTCCGTGAAAGAAGAAATGTTGCTACCTCAACTGAAAAATCTGTGGCATGG
  CAAAATTCAAATGAGGAGAATTCATCTTCCATCTTTCCTTATGGAGAGACCTTTCTCTTC
  CAGAGACTAGAAAATTCCAAGAAGCGATCTATAAAGAATGAATTTTTGACCCAGGGAGAA
  GCACTCAAAGGGGAAGCAGCTACTGCAACAAACTCTTTTATCATCAAATCAAGCATATAC
  GATAACAGAAAGGAGAAAATAAGCGAGGACAAGGTGGAAGATATTTGGATACCTCGAGAG
  GACAAAAACAATTTTTTGATAGACACTGCTTCTGAATCAGAATACTCAACAGTAGAAGAA
  TGCTTTCAGAGTTTAAGAAGAAAAAATTCAAAGGCATCTAAATCTAGGACTCAAAAAGCC
  TTGATTTTGGACTCCGTTAATAGGCACAGTTATCCGTTAAGCTCAACAAGTGGAAATGCT
  GATTCATCAGCCGTTTCTTCACAGGCAATATCTCCCTATGCCTGCTTTTATGGAGCATCT
  GCAAAGAAGGTTAAATCAGGATGGCTGGATAAACTCTCTCCTCAAGGAAAACGCATGTTT
  CAAAAGAGATGGGTGAAATTTGATGGCCTTAGCATTTCTTACTACAATAATGAGAAGGAG
  ATGTATTCGAAAGGAATAATTCCCCTTTCTGCTATATCAACAGTACGAGTTCAAGGAGAC
  AACAAATTTGAAGTTGTTACAACACAAAGAACTTTTGTTTTTAGAGTAGAAAAAGAAGAG
  GAGAGAAATGACTGGATCAGCATACTATTAAATGCACTGAAATCACAATCCCTTACCTCG
  CAGTCTCAAGCTGTTGTTACACCTGAGAAATGTGGATATCTTGAATTGAGAGGCTATAAG
  GCAAAAATTTTTACTGTGTTAAGTGGAAACAGTGTGTGGCTTTGCAAAAACGAACAGGAT
  TTTAAGAGTGGACTTGGTATTACCATAATTCCTATGAATGTAGCAAATGTAAAGCAAGTG
  GACCGAACTGTGAAACAATCTTTTGAAATAATCACTCCCTACAGGAGTTTCAGCTTTACA
  GCCGAGACTGAAAAGGAGAAACAAGACTGGATTGAAGCTGTGCAGCAATCAATAGCAGAA
  ACTCTCTCTGATTATGAAGTAGCTGAGAAGATTTGGTTCAATGAATCCAACAGGAGCTGT
  GCAGATTGTAAAGCCCCAGATCCTGACTGGGCATCCATCAATCTCTGTGTTGTCATCTGT
  AAGAAGTGTGCAGGACAGCATAGATCTTTAGGACCAAAAGATTCCAAGGTTAGAAGTCTA
  AAAATGGATGCTAGCATTTGGAGCAATGAACTCATCGAGCTTTTTATTGTCATTGGAAAC
  AAAAGAGCAAATGACTTTTGGGCTGGTAATCTTCAAAAGGATGAAGAATTACATATGGAC
  TCACCAGTAGAAAAGAGAAAAAACTTTATTACTCAGAAATATAAAGAAGGAAAATTCAGA
  AAAACTCTTTTGGCATCTCTCACCAAAGAAGAATTAAATAAGGCTCTATGTGCTGCTGTA
  GTGAAACCGGATGTTCTAGAAACAATGGCTTTGCTGTTCAGTGGAGCAGATGTCATGTGT
  GCCACCGGAGACCCCGTGCATAGCACCCCCTATCTGCTAGCCAAGAAAGCTGGGCAAAGT
  CTGCAAATGGAATTTCTCTACCATAACAAATTCTCAGATTTCCCTCAACATGATATTCAT
  TCCGAGGGTGTATTAAGTCAAGAGTCTTCCCAGTCCACATTCCTCTGTGACTTTTTATAT
  CAAGCTCCTTCTGCTGCTTCTAAACTCTCTTCAGAGAAAAAACTGCTTGAAGAGACAAAT
  AAAAAATGGTGTGTTTTGGAAGGAGGCTTCTTGAGTTACTATGAAAATGATAAGTCTACC
  ACACCTAATGACACCATTAATATCAATGAAGTTATCTGCCTGGCTATACACAAAGAGGAC
  TTCTATTTAAATACTGGGCCCATCTTTATCTTTGAGATCTACTTACCCTCCGAACGTGTG
  TTTTTATTTGGAGCTGAAACATCTCAAGCTCAAAGAAAATGGACAGAGGCAATAGCCAAG
  CATTTTGTTCCCTTATTTGCTGAAAACTTAACAGAAGCTGACTATGATTTGATTGGTCAA
  CTCTTCTACAAAGACTGCCATGCCCTGGATCAGTGGAGAAAAGGCTGGTTTGCTATGGAC
  AAATCCAGCTTGCATTTTTGCCTTCAAATGCAAGAAGTTCAGGGAGATAGAATGCACTTA
  AGAAGACTGCAAGAGCTAACAATCAGCACAATGGTTCAAAATGGGGAAAAACTGGATGTT
  TTACTCTTGGTAGAAAAAGGGAGAACATTATACATCCATGGGCATACCAAGTTGGATTTC
  ACAGTCTGGCATACTGCAATTGAAAAAGCAGCAGGTACAGATGGTAATGCTTTACAAGAT
  CAGCAGCTCAGCAAAAATGACGTTCCCATTATAGTGAACAGCTGTATAGCATTTGTTACA
  CAGTATGGTTTAGGATGCAAATATATCTATCAAAAGAATGGTGATCCTTTGCATATAAGT
  GAACTCCTGGAGAGTTTCAAAAAGGATGCAAGAAGCTTTAAATTGAGGGCTGGAAAACAT
  CAGCTTGAAGATGTGACGGCTGTGTTGAAAAGTTTTCTCTCTGACATTGATGATGCACTG
  CTTACTAAGGAGCTCTACCCATATTGGATCTCTGCTTTAGATACGCAAGATGACAAGGAA
  AGAATTAAAAAATATGGAGCATTTATACGTTCTCTTCCAGGGGTCAACCGAGCAACACTA
  GCAGCTATCATTGAACACCTGTATAGGGTTCAGAAATGCTCAGAAATCAATCACATGAAT
  GCCCATAATTTGGCCTTGGTCTTTTCATCCTGTTTGTTTCAAACGAAGGGACAAACTAGT
  GAAGAAGTGAATGTAATTGAGGACCTAATTAATAATTATGTAGAAATATTTGAGGTTAAA
  GAAGATCAAGTCAAACAAATGGACATAGAAAATAGCTTTATTACCAAGTGGAAAGACACC
  CAAGTTTCCCAGGCTGGAGATTTGTTAATTGAAGTATATGTAGAAAGGAAGGAACCCGAC
  TGTAGTATTATAATTCGGATATCTCCTGTGATGGAAGCAGAAGAATTAACTAATGATATA
  TTAGCGATAAAAAATATTATTCCTACAAAAGGTGATATTTGGGCCACATTTGAAGTCATT
  GAAAATGAAGAGCTAGAGCGTCCTCTTCACTACAAGGAAAATGTACTGGAGCAGGTGCTT
  CGGTGGAGTTCATTAGCTGAACCTGGCTCTGCTTACCTGGTGGTGAAGAGATTCTTAACC
  GCTGACACAATTAAACACTGCAGTGACCGGAGTACACTGGGAAGCATCAAAGAAGGAATC
  TTGAAAATCAAAGAAGAACCATCCAAAATACTATCTGGAAATAAGTTTCAAGACCGGTAT
  TTTGTTTTACGAGATGGGTTTCTCTTTCTTTACAAGGATGTGAAGAGTAGTAAACATGAC
  AAGATGTTTTCTCTCAGTTCCATGAAGTTTTATCGTGGAGTGAAAAAGAAAATGAAGCCT
  CCAACAAGCTGGGGATTGACCGCATATTCTGAGAAACATCACTGGCACCTGTGTTGTGAT
  AGTTCACAAACTCAGACGGAGTGGATGACCAGTATCTTTATTGCCCAGCATGAATATGAT
  ATATGGCCACCAGCTGGAAAGGAACGAAAACGTTCAATAACCAAAAATCCCAAAATTGGA
  GGTTTGCCTCTGATTCCTATACAGCATGAGGGGAATGCAACCTTGGCCCGGAAAAATATT
  GAGAGTGCAAGAGCAGAACTTGAAAGGCTGCGGCTCAGTGAAAAGTGTGATAAAGAGTCC
  GTGGACTCTAGCTTAAAGGAGAGAGCTTCCATGGTGGCCCACTGCCTGGAGCACAAGGAC
  GATAAACTTCGAAATCGACCCCGAAAACATCGGAGTTTCAACTGCCTGGAGGACACAGAG
  CCTGAAGCCCCACTTGGGCAACCAAAAGGCCATAAAGGCCTAAAGACATTGAGGAAGACT
  GAGGACAGGAATAGCAAAGCTACTTTGGACTCTGATCATAAGTTACCATCAAGGGTAATT
  GAAGAACTTAATGTGGTTCTACAACGGTCAAGAACCCTTCCAAAAGAATTACAGGATGAG
  CAGATTTTGAAGTAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015230 unedited
  ACTTAGGGCGGCCGCCAATTCGGCACGAGGGATCCGGATAGACAGCTGGACACTCCCTCC
  ATTCCTCTCCCCTACCTTTAAATAAGAAGAAGCTGTAGTGAGTTTCAGGCACCAAGTTAT
  TTACTCGGTAGAGATCATGAATTTGCCCGGGTGTCTGTGCTGCCCCGCACCCTGCTTGTT
  AACCACGTTAAGACGACTGGCCTGTTAATTAACTTTAATTACGATCATTTGGCTTCCACC
  TGCCTGAACCCGATACCTTACACGGGAACCTGTATGATGTGAGTTTACCAGATTGATCTT
  TCTTGTTTACTTTTGGAGACAGTTCTCTTGGGAGAAGTGGTGTCCATCCTATTTAATAAA
  GCTTAAGCAGGTAAAGCAGTCACTGTGAAGAAAATAACATTTTAAGAAACTTTTCTGTCA
  CAATTGATAGAGGAAAAGCCAGTAGAGAAGTACATCTTCTTGTGTGTGTGTCTCATCGTG
  CCACTTTTTGTAACTCAGCTTAGTAATGAAGCCACCATTATGTCCTCAGTCAGTGAAGTA
  AATGTGGATATAAAAGATTTCCTAATGAGCATTAATTTGGAGCAGTATCTCTTACATTTC
  CATGAGTCTGGTTTTACTACTGTGAACGACTGTGCAGCAATAAATGACAGCCTGCTGCAG
  AAAATTGGAATATCACCTACAGGTCACCGTAGGAGGATACTTAAACAGTTACAGATAATC
  TTGTCAAAAATGCANGATTATTCCATATATGCAAATGTTCATAAAACTA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015230 unedited
  NGGCCCATGGGCGATTGGCCAACTTCCCAGGGCCAGGNGAAAGCCACTGGGGNAGTGGGT
  CACAGGGCATGCCACCCGGGCTCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAG
  AGTCGAGTTTTTTTTTTTTTTTTTTAGACTTGTAAAACAATTTTAATGTTTACTCAAAAT
  AAATGAGATGTCATCATTAGCCCTTATCTCTCACACTTGAAAAATGGAGACAGTTGTTCA
  GAATAGAAAGGGAAACAGCTATTAGAGTTTAAGCTCAAGTTTCAAGAAGAATTCAGATAA
  GGCAGGTAAAAACTCTAGATACTTTTCCACTGTCCAACATCACCAAATATTAATTTCCAC
  ATACCTCTTTATTTCATAAAAATATAAATATTTATTAGAAATAGTATGTTTAAGATTAGT
  TTTTCTTTCTAAATAACATGATTTCTTGCTTTAAAGGAAGATTCCCTAATAGTGCCACCT
  ATTTCATAAACTGTCCTGCAGTTTTGTGCTTTTTAAAAATTCTAATTTACTTTGATTTAA
  AGAATAAATATCTCATACCCATGGTGAACTATTTTATCACCCCAAAATACAAATGATCCG
  TATTTTACAATGAAGAAATTCATAGCATCTACCACCACATCACTGTACTATGATTGGACT
  GACTGAAGTATGGGCCTGTGAATATAGATTGAAAAATAAAAAAGAAATGCTAAAAAAAAA
  AACTTAGCTACTTAATGTTTAATATCAAAACTTCACAAACAATCCAATTTTAAAAAACTG
  AGGGAAAATGCCTCCCCCTACCTGAACTAGGGTTAAATAGCATTGTCTGTCAGGAAATTC
  ACCCATTTCATAGCTGATCCTTTAGTGGAAACAAAAAAGGGCTTTTGCCTTTTTCTAAGT
  GCGGGGAAAGGCCCCCCCTTTCCTAAAAAAAAAAAAAACCCTTTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015230
• ORF Size: 5115 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015230.2, NP_056045.2
• RefSeq Size: 7360
• RefSeq ORF: 5115
• Locus ID: 116984
• Domains: RhoGAP, ArfGap, SAM, PH
• Protein Pathways: Endocytosis
• Gene Summary: The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
  Transcript Variant: This variant (1) represents the protein-coding transcript and encodes the supported protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.