BAAT1 (BRAT1) (NM_152743) Human Untagged Clone

CAT#: SC126644

BRAT1 (untagged)-Human BRCA1-associated ATM activator 1 (BRAT1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BRAT1
• Synonyms: BAAT1; C7orf27; NEDCAS; RMFSL
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126644 sequence for NM_152743 edited (data generated by NextGen Sequencing)
  ATGGACCCAGAATGCGCCCAGCTGCTCCCGGCTCTCTGTGCTGTTCTGGTAGATCCCAGG
  CAGCCGGTGGCAGATGACACCTGTTTGGAGAAGCTCCTGGACTGGTTTAAAACGGTCACT
  GAAGGAGAGTCCAGTGTCGTGCTGCTGCAGGAGCACCCCTGCCTGGTGGAGCTGCTGTCC
  CATGTGCTGAAAGTCCAGGACCTGAGTTCTGGGGTCCTCTCCTTCTCACTGCGCCTGGCA
  GGAACCTTCGCAGCCCAGGAAAACTGCTTCTAGTATCTTCAGCAGGGGGAGTTACTACCA
  GGGCTCTTTGGGGAGCCAGGACCCCTCGGCCGAGCAACCTGGGCCGTCCCCACCGTGCGC
  AGCGGCTGGATCCAGGGCCTGCGCTCCCTGGCACAGCACCCCAGCGCCCTGCGCTTCCTG
  GCCGACCATGGTGCGGTCGACACCATCTTCTCCCTGCAGGGAGACTCCAGCCTGTTTGTG
  GCCTCGGCGGCCAGTCAGCTCCTGGTGCACGTCCTGGCTTTGTCCATGCGAGGTGGAGCC
  GAGGGGCAGCCCTGCCTGCCGGGGGGTGACTGGCCCGCGTGTGCCCAGAAGATCATGGAT
  CACGTTGAAGAGTCCTTGTGCTCCGCGGCCACCCCCAAGGTCACTCAGGCCCTGAACGTC
  CTGACCACGACCTTCGGGCGCTGCCAGAGCCCCTGGACAGAAGCCCTGTGGGTGCGGCTG
  AGTCCCCGCGTGGCCTGTCTGCTGGAGAGAGACCCCATCCCCGCCGCACACTCGTTCGTG
  GACCTGCTTCTCTGTGTGGCTCGTTCTCCCGTGTTCAGTTCTTCCGACGGCAGCCTGTGG
  GAGACAGTGGCGCGGGCTCTGAGCTGCCTGGGTCCCACCCACATGGGACCCCTGGCTTTG
  GGGATCCTGAAGCTCGAGCACTGTCCACAGGCACTGAGGACCCAGGCCTTCCAGGTCCTT
  CTCCAGCCCCTGGCCTGTGTCCTGAAGGCCACGGTTCAGGCCCCCGGACCCCCAGGCTTG
  CTGGACGGGACGGCAGACGATGCCACGACGGTGGACACACTCCTGGCCTCCAAGTCGTCC
  TGCGCCGGCCTCCTGTGCCGCACCCTGGCTCACCTGGAGGAGCTGCAGCCGCTGCCCCAG
  CGCCCTTCACCGTGGCCCCAGGCGTCTCTACTGGGGGCTACAGTGACTGTCCTGCGGCTC
  TGTGACGGCTCGGCTGCCCCTGCCTCCAGTGTGGGGGGCCACCTCTGTGGGACCCTGGCG
  GGCTGCGTCCGGGTCCAGCGAGCAGCCCTCGACTTCCTGGGGACGCTGTCACAGGGGACA
  GGCCCCCAGGAGCTGGTGACGCAGGCGCTTGCTGTCCTCCTGGAGTGCCTCGAGAGCCCC
  GGCTCCAGCCCCACGGTTCTGAAGAAGGCCTTCCAGGCCACGCTCAGGTGGCTCCTGAGC
  TCACCCAAGACCCCCGGCTGCTCTGATCTCGGCCCCCTCATCCCGCAGTTCCTCAGAGAG
  CTGTTCCCTGTGCTGCAGAAACGCCTGTGCCACCCCTGCTGGGAGGTGAGGGACTCCGCC
  CTCGAGTTCCTGACCCAGCTGAGCAGGCACTGGGGAGGACAGGCTGACTTCAGATGCGCA
  CTCTTGGCTTCAGAGGTGCCTCAGCTGGCCCTGCAGCTCCTCCAGGACCCTGAGAGTTAT
  GTCCGAGCGAGTGCAGTGACCGCCATGGGGCAGCTGTCCAGCCAGGGCCTGCACGCCCCC
  ACCAGCCCTGAGCATGCAGAGGCCCGGCAGAGCCTGTTCCTGGAGCTCCTGCACATCCTC
  TCCGTAGACTCGGAGGGCTTCCCACGGCGGGCGGTCATGCAAGTCTTCACTGAGTGGCTG
  CGGGACGGCCACGCCGACGCGGCCCAGGACACGGAGCAGTTCGTGGCCACTGTGCTGCAG
  GCGGCGAGCCNNNACCTGGACTGGGAGGTCCGCGCCCAGGGCCTGGAGCTGGCCCTCGTG
  TTCCTGGGCCAGACTTTGGGGCCGCCGCGTACCCACTGCCCCTATGCCGTGGCCCTACCC
  GAGGTGGCCCCAGCCCAGCCACTCACCGAGGCACTGAGGGCTCTCTGCCACGTGGGGCTC
  TTTGACTTCGCCTTTTGTGCCTTGTTTGACTGCGACCGCCCTGTGGCGCAGAAGTCTTGT
  GACCTCCTTCTCTTCCTGAGGGACAAGATTGCTTCCTACAGCAGCCTGCGGGAGGCCAGG
  GGCAGCCCCAACACTGCCTCCGCAGAGGCCACCCTGCCGAGGTGGCGGGCGGGTGAGCAG
  GCCCAGCCCCCAGGGGACCAGGAGCCTGAGGCTGTGCTGGCCATGCTCAGGTCCCTAGAC
  CTGGAGGGCCTGCGGAGCACGCTGGCCGAGAGCAGCGACCACGTGGAGAAGAGTCCCCAG
  TCCCTCCTGCAGGACATGCTGGCCACGGGAGGCTTCCTGCAGGGGGACGAGGCCGACTGC
  TACTGA
  
  Clone variation with respect to NM_152743.3
  271 c=>t;699 g=>a;1931 g=>n;1932 a=>n;1933 g=>n;2388 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152743 unedited
  GCACGAGGGGCCTGCGGCCTCACCATGGACCCAGAATGCGCCCAGCTGCTCCCGGCTCTC
  TGTGCTGTTCTGGTAGATCCCAGGCAGCCGGTGGCAGATGACACCTGTTTGGAGAAGCTC
  CTGGACTGGTTTAAAACGGTCACTGAAGGAGAGTCCAGTGTCGTGCTGCTGCAGGAGCAC
  CCCTGCCTGGTGGAGCTGCTGTCCCATGTGCTGAAAGTCCAGGACCTGAGTTCTGGGGTC
  CTCTCCTTCTCACTGCGCCTGGCAGGAACCTTCGCAGCCCAGGAAAACTGCTTCTAGTAT
  CTTCAGCAGGGGGAGTTACTACCAGGGCTCTTTGGGGAGCCAGGACCCCTCGGCCGAGCA
  ACCTGGGCCGTCCCCACCGTGCGCAGCGGCTGGATCCAGGGCCTGCGCTCCCTGGCACAG
  CACCCCAGCGCCCTGCGCTTCCTGGCCGACCATGGTGCGGTCGACACCATCTTCTCCCTG
  CAGGGAGACTCCAGCCTGTTTGTGGCCTCGGCGGCCAGTCAGCTCCTGGTGCACGTCCTG
  GCTTTGTCCATGCGAGGTGGAGCCGAGGGGCAGCCCTGCCTGCCGGNGGGTGACTGGCCC
  GCGTGTGCCCAGAAGATCATGGATCACGTTGAAGAGTCCTTGTGCTCCGCGGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_152743 unedited
  ATAACTGGGTTGTGTCCGCATCGANGTTCNGTTTTAATTTTTTTTTTTTTTGAGTAGAAA
  TTTTTCATTTCTTTAATACATCAAACTGTGGGATTTCTTGACCTTGCTTCTCTCCTGGTC
  CTGGCTTCCCCAGAGGATCCACCGGGCTGGGCTGGAGCCCTGGGGCTGGCAGTGTCCCAC
  AGAAGGACATGGTGCTGCCTCCCTTGGTCCTGATCCCCAGTGGCAGAGTCTGGTTCTGCT
  CAGTAGCAGTCGGCCTCGTCCCCCTGCAGGAAGCCTCCCGTGGCCAGCATGTCCTGCAGG
  AGGGACTGGGGACTCTTCTCCACGTGGTCGCTGCTCTCGGCCAGCGTGCTCCGCAGGCCC
  TCCAGGTCTAGGGACCTGAGCATGGCCAGCACAGCCTCAGGCTCCTGGTCCCCTGGGGGC
  TGGGCCTGCTCACCCGCCCGCCACCTCGGCAGGGTGGCCTCTGCGGAGGCAGTGTTGGGG
  CTGCCCCTGGCCTCCCGCAGGCTGCTGTAGGAAGCAATCTTGTCCCTCANGAAGAGAAGG
  AGGTCACAAGACTTCTGCGCCACAGGGCGGTCGCAGTCAAACAAGGCACAAAAGGCGAAG
  TCAAAGAGCCCCACGTGGCAGAGAGCCCTCAGTGCCTCGGTGAGTGGCTGGGCTGGGGCC
  ACCTCGGGTAGGGCCACGGCATATGGGCAGTGGGTACGCGGCGGCCCCAAAGTCTGGCCC
  CAGGACACGATGGCCAGCTTCAGGCCCTGGGCGCGGACCTNCCAGTCCAGGTCCTGGCTC
  GCCGCCTGCAGCCAGTGGCCACGAACTGCTCCGTGTCCTTGGCCGCGTCGGCGTGGCCGT
  CCCGCACCACTCAGTGAAGACCTGCATGACCCGCCCNCCGTGGGAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_152743
• ORF Size: 2466 bp
• Insert Size: 2850
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_152743.2, NP_689956.1
• RefSeq Size: 2713
• RefSeq ORF: 2466
• Locus ID: 221927
• Gene Summary: The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
  Transcript Variant: This variant (2) uses an alternate in-frame splice junction in the 3' end of the coding sequence compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.