BAAT1 (BRAT1) (NM_152743) Human Untagged Clone

CAT#: SC320446

BRAT1 (untagged)-Human BRCA1-associated ATM activator 1 (BRAT1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BRAT1
• Synonyms: BAAT1; C7orf27; NEDCAS; RMFSL
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_152743.2 GTTGCGGCGGAGGACGCAACCGAGCGGGCCTGCGGCCTCACCATGGACCCAGAATGCGCC
  CAGCTGCTCCCGGCTCTCTGTGCTGTTCTGGTAGATCCCGGGCAGCCGGTGGCAGATGAC
  ACCTGTTTGGAGAAGCTCCTGGACTGGTTTAAAACGGTCACTGAAGGAGAGTCCAGTGTC
  GTGCTGCTGCAGGAGCACCCCTGCCTGGTGGAGCTGCTGTCCCATGTGCTGAAAGTCCAG
  GACCTGAGTTCTGGGGTCCTCTCCTTCTCACTGCGCCTGGCAGGAACCTTCGCAGCCCAG
  GAAAACTGCTTCCAGTATCTTCAGCAGGGGGAGTTACTACCAGGGCTCTTTGGGGAGCCA
  GGACCCCTCGGCCGAGCAACCTGGGCCGTCCCCACCGTGCGCAGCGGCTGGATCCAGGGC
  CTGCGCTCCCTGGCACAGCACCCCAGCGCCCTGCGCTTCCTGGCCGACCATGGTGCGGTC
  GACACCATCTTCTCCCTGCAGGGAGACTCCAGCCTGTTTGTGGCCTCGGCGGCCAGTCAG
  CTCCTGGTGCACGTCCTGGCTTTGTCCATGCGAGGTGGAGCCGAGGGGCAGCCCTGCCTG
  CCGGGGGGTGACTGGCCCGCGTGTGCCCAGAAGATCATGGATCACGTTGAAGAGTCCTTG
  TGCTCCGCGGCCACCCCCAAGGTCACTCAGGCCCTGAACGTCCTGACCACGACCTTCGGG
  CGCTGCCAGAGCCCCTGGACGGAAGCCCTGTGGGTGCGGCTGAGTCCCCGCGTGGCCTGT
  CTGCTGGAGAGAGACCCCATCCCCGCCGCACACTCGTTCGTGGACCTGCTTCTCTGTGTG
  GCTCGTTCTCCCGTGTTCAGTTCTTCCGACGGCAGCCTGTGGGAGACAGTGGCGCGGGCT
  CTGAGCTGCCTGGGTCCCACCCACATGGGACCCCTGGCTTTGGGGATCCTGAAGCTCGAG
  CACTGTCCACAGGCACTGAGGACCCAGGCCTTCCAGGTCCTTCTCCAGCCCCTGGCCTGT
  GTCCTGAAGGCCACGGTTCAGGCCCCCGGACCCCCAGGCTTGCTGGACGGGACGGCAGAC
  GATGCCACGACGGTGGACACACTCCTGGCCTCCAAGTCGTCCTGCGCCGGCCTCCTGTGC
  CGCACCCTGGCTCACCTGGAGGAGCTGCAGCCGCTGCCCCAGCGCCCTTCACCGTGGCCC
  CAGGCGTCTCTACTGGGGGCTACAGTGACTGTCCTGCGGCTCTGTGACGGCTCGGCTGCC
  CCTGCCTCCAGTGTGGGGGGCCACCTCTGTGGGACCCTGGCGGGCTGCGTCCGGGTCCAG
  CGAGCAGCCCTCGACTTCCTGGGGACGCTGTCACAGGGGACAGGCCCCCAGGAGCTGGTG
  ACGCAGGCGCTTGCTGTCCTCCTGGAGTGCCTCGAGAGCCCCGGCTCCAGCCCCACGGTT
  CTGAAGAAGGCCTTCCAGGCCACGCTCAGGTGGCTCCTGAGCTCACCCAAGACCCCCGGC
  TGCTCTGATCTCGGCCCCCTCATCCCGCAGTTCCTCAGAGAGCTGTTCCCTGTGCTGCAG
  AAACGCCTGTGCCACCCCTGCTGGGAGGTGAGGGACTCCGCCCTCGAGTTCCTGACCCAG
  CTGAGCAGGCACTGGGGAGGACAGGCTGACTTCAGATGCGCACTCTTGGCTTCAGAGGTG
  CCTCAGCTGGCCCTGCAGCTCCTCCAGGACCCTGAGAGTTATGTCCGAGCGAGTGCAGTG
  ACCGCCATGGGGCAGCTGTCCAGCCAGGGCCTGCACGCCCCCACCAGCCCTGAGCATGCA
  GAGGCCCGGCAGAGCCTGTTCCTGGAGCTCCTGCACATCCTCTCCGTAGACTCGGAGGGC
  TTCCCACGGCGGGCGGTCATGCAAGTCTTCACTGAGTGGCTGCGGGACGGCCACGCCGAC
  GCGGCCCAGGACACGGAGCAGTTCGTGGCCACTGTGCTGCAGGCGGCGAGCCGAGACCTG
  GACTGGGAGGTCCGCGCCCAGGGCCTGGAGCTGGCCCTCGTGTTCCTGGGCCAGACTTTG
  GGGCCGCCGCGTACCCACTGCCCCTATGCCGTGGCCCTACCCGAGGTGGCCCCAGCCCAG
  CCACTCACCGAGGCACTGAGGGCTCTCTGCCACGTGGGGCTCTTTGACTTCGCCTTTTGT
  GCCTTGTTTGACTGCGACCGCCCTGTGGCGCAGAAGTCTTGTGACCTCCTTCTCTTCCTG
  AGGGACAAGATTGCTTCCTACAGCAGCCTGCGGGAGGCCAGGGGCAGCCCCAACACTGCC
  TCCGCAGAGGCCACCCTGCCGAGGTGGCGGGCGGGTGAGCAGGCCCAGCCCCCAGGGGAC
  CAGGAGCCTGAGGCTGTGCTGGCCATGCTCAGGTCCCTAGACCTGGAGGGCCTGCGGAGC
  ACGCTGGCCGAGAGCAGCGACCACGTGGAAAAGAGTCCCCAGTCCCTCCTGCAGGACATG
  CTGGCCACGGGAGGCTTCCTGCAGGGGGACGAGGCCGACTGCTACTGAGCAGAACCAGAG
  TCTGCCACTGGGGCTCAGGACCAAGGGAGGCAGCACCATGTCCTTCTGTGGGACACTGCC
  AGCCCCAGGGCTCCAGCCCAGCCCGGTGGATCCTCTGGGGAAGCCAGGACCAGGAGAGAA
  GCAAGGTCAAGAAATCCCACAGTTTGATGTATTAAAGAAATGACTTATTTCTACTCAAAA
  AAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152743.2 unedited
  CAACTACTGACTATATGGTATACTACTACTACCCGTGCGTGCCGGGAATTCGTCGACTGG
  ATCCGGTACCGAGGAGTATCGCTTAACTAGTTAGCGGACCGACGCGTTAAGCGGCCGCGA
  ATTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTTGTAAAACGACGGCCAGTAACTATA
  ACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTCGGCACGAGGGTTGCGGCGGAGGAC
  GCAACCGAGCGGGCCTGCGGCCTCACCATGGACCCAGAATGCGCCCAGCTGCTCCCGGCT
  CTCTGTGCTGTTCTGGTAGATCCCGGGCAGCCGGTGGCAGATGACACCTGTTTGGAGAAG
  CTCCTGGACTGGTTTAAAACGGTCACTGAAGGAGAGTCCAGTGTCGTGCTGCTGCAGGAG
  CACCCCTGCCTGGTGGAGCTGCTGTCCCATGTGCTGAAAGTCCAGGACCTGAGTTCTGGG
  GTCCTCTCCTTCTCACTGCGCCTGGCAGGAACCTTCGCAGCCCAGGAAACTGCTTCCAGT
  ATCTTCAGCAGGGGGAGTTACTACCAGGGCTCTTTGGGGAGCCAGGACCCCTCGGCCGAG
  CAACCTGGGCCGTCCCCACCGTGCGCAGCGGCTGGATCCAGGGCCTGCGCTCCCTGGCAC
  AGCACCCCAGCGCCCTGCGCTTCCTGGCCGACCATGGTGCGGTCGACACCATCTTCTCCC
  TGCAGGAGACTCCAGCCTGTTTGTGGCCTCGGCGGCCAGTCAGCTCCTGTGCACGTCCTG
  GCTTTGTCCATGCGAGGTGGAGCCGAGGGGCAGCCCTGCCTGCCGGGGGGGTGACTGGCC
  CGCGTGTGCCCAGAGATCATGGATCACGTGAGAGTCTGTGCTCCGCGGGCCACCCCCCAA
  GTCACTCAAGCCCTGACCGTCTGAACCACGACTCGTGCGCCTGCCAAAGCCCCTGGGAAC
  GGAGCCCTTTTGAGT
• Restriction Sites: Please inquire
• ACCN: NM_152743
• ORF Size: 2466 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_152743.2, NP_689956.1
• RefSeq Size: 2713
• RefSeq ORF: 2466
• Locus ID: 221927
• Gene Summary: The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
  Transcript Variant: This variant (2) uses an alternate in-frame splice junction in the 3' end of the coding sequence compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.