UBE1C (NM_198197) Human Untagged Clone

CAT#: SC127005

UBE1C (untagged)-Human ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) (UBE1C), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBE1C
• Synonyms: UBA3, hUba3, MGC22384, DKFZp566J164
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127005 sequence for NM_198197 edited (data generated by NextGen Sequencing)
  ATGGACACTATAGATGTTTCCAATCTAAATAGGCAGTTTTTATTTAGGCCTAAAGATATT
  GGAAGACCTAAGGCTGAAGTTGCTGCAGAATTTCTAAATGACAGAGTTCCTAATTGCAAT
  GTAGTTCCACATTTCAACAAGATTCAAGATTTTAACGACACTTTCTATCGACAATTTCAT
  ATTATTGTATGTGGACTGGACTCTATCATCGCCAGAAGATGGATAAATGGCATGCTGATA
  TCTCTTCTAAATTATGAAGATGGTGTCTTAGATCCAAGCTCCATTGTCCCTTTGATAGAT
  GGGGGGACAGAAGGTTTTAAAGGAAATGCCCGGGTGATTCTGCCTGGAATGACTGCTTGT
  ATCGAATGCACGCTGGAACTTTATCCACCACAGGTTAATTTTCCCATGTGCACCATTGCA
  TCTATGCCCAGGCTACCAGAACACTGTATTGAGTATGTAAGGATGTTGCAGTGGCCTAAG
  GAGCAGCCTTTTGGAGAAGGGGTTCCATTAGATGGAGATGATCCTGAACATATACAATGG
  ATTTTCCAAAAATCCCTAGAGAGAGCATCACAATATAATATTAGGGGTGTTACGTATAGG
  CTCACTCAAGGGGTAGTAAAAAGAATCATTCCTGCAGTAGCTTCCACAAATGCAGTCATT
  GCAGCTGTGTGTGCCACTGAGGTTTTTAAAATAGCCACAAGTGCATACATTCCCTTGAAT
  AATTACTTGGTGTTTAATGATGTAGATGGGCTGTATACATACACATTTGAAGCAGAAAGA
  AAGGAAAACTGCCCAGCTTGTAGCCAGCTTCCTCAAAATATTCAGTTTTCTCCATCAGCT
  AAACTACAGGAGGTTTTGGATTATCTAACCAATAGTGCTTCTCTGCAAATGAAATCTCCA
  GCCATCACAGCCACCCTAGAGGGAAAAAATAGAACACTTTACTTACAGTCGGTAACCTCT
  ATTGAAGAACGAACAAGGCCAAATCTCTCCAAAACATTGAAAGAATTGGGGCTTGTTGAT
  GGACAAGAACTGGCGGTTGCTGATGTCACCACCCCACAGACTGTACTATTCAAACTTCAT
  TTTACTTCTTAA
  
  Clone variation with respect to NM_198197.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_198197 unedited
  TATTTTCCCGCCCGTTGCCGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG
  CAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGC
  GAATTCGGCACGAGGGGATGGCGAGGAGCCGGTAGAAGAAAAGAAGGAGAATAGAGGAGC
  TGCTGGCTGAGAAAATGGCTGTTGATGGTGGGTGTGGGGACACTGGAGACTGGGAAGGTC
  GCTGGAACCATGTAAAGAAGTTCCTCGAGCGATCTGGACCCTTCACACACCCTGATTTCG
  AACCGAGCACTGAATCTCTCCAGTTCTTGTTAGATACATGTAAAGTTCTAGTCATTGGAG
  CTGGCGGCTTAGGATGTGAGCTCCTGAAAAATCTGGCCTTGTCTGGTTTTAGACAGATTC
  ATGTTATAGATATGGACACTATAGATGTTTCCAATCTAAATAGGCAGTTTTTATTTAGGC
  CTAAAGATATTGGAAGACCTAAGGCTGAAGTTGCTGCAGAATTTCTAAATGACAGAGTTC
  CTAATTGCAATGTAGTTCCACATTTCAACAAGATTCAAGATTTTAACGACACTTTCTATC
  GACAATTTCATATTATTGTATGTGGACTGGACTCTATCATCGCCAGAAGATGGATAAATG
  GCATGCTGATATCTCTTCTAAATATGAAGAGGTGTCTTAGATCCAGCTCCATGTCCCTTT
  GATAGATGGGGGACAGAAGGNTTTAAAGGAATGCCCGGNTGATTCTGCCTGGAAGACTGC
  CTGTATACAATGCACCCTGAAACTTATCCCCACAGGTTAATTTTCCATGTGCCCATTGCA
  CTTATGCCCAGCTACCCAAAACCTNATTGAGTATGTAAGATGTTGCAGGGCCCTAAGGAC
  CGCCTTTGAGAAGGGGTTCATTAAAAGGAAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_198197 unedited
  CCCCCCAATAGTTGTCCGCGGCCCATTCTANGATCNGTTTTTTTTTTTTTTTTTTACACA
  ATATATGATTTTATTAATAAATAGTGCAAAAGCATCAGTGATAACTGTTTGAACATTAAA
  TTTTTTAAACAGCCATGTCTTGGCATTAGTTAATATTGTGCATATTGGCCTCTATGGCAC
  TACAAGTAAACAGATGAAAATATTGCCCATTTTCATGCTCAGTTATTCAGCTATAACACC
  ATTTACAAATCATTATGAACAAGATAAATTCTGCAATAATATTCATTTGGATGGCCACAA
  TTAAATGAGTGTTATATCAAGAAATAGCCTATGTTCAATATACTCCAGATGTCAGATTGT
  AAAATGTAATGTTATTTAAAACTTAATTCTTTATTTTCCTTAAAGGGACACCTTTTGTGT
  ATTTGGGTACTCAAATGAAAACTTAGGAATGCATTCTTTGACCATAATAACAAAATTCAC
  ACAAAAGAGGTTGTATGCTTCCTCCTCTAAAAGAAGCAATACATTTGCTCATAATCTCTC
  TCTCCAGGTATCATTTCTCATATTATTAATGAAAATGCTTACAAGCACCAACACCAAAAT
  TCTGTCTTCAAGGGAAGGTTACAAAGTTAAAAAAGAGTGGGTCATTATATAAAAAAAGAC
  AAATCGTGGCAACACTATTGCTAAAAATGACATCTGATTTAACTTCTTAGCATCCACAAA
  GTATATTATTTTCCATGAGTTTTTCTATTATGTGGGAGATTTTCCCTTAAGAAGTAAAAT
  GAAGTTTGCATAGTACAGTCTGTGGGGTGAGGACATCAGCAACCGCAGTTTCTGTCCACA
  ACAACCCCAAATTTTTTAATGTTTTGGAGAGATTGCGCCCTGTTCCGCTCTTCAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_198197
• ORF Size: 1092 bp
• Insert Size: 2300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_198197.1, NP_937840.1
• RefSeq Size: 2015
• RefSeq ORF: 1092
• Locus ID: 9039
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) lacks an exon in the 5' region and uses a downstream start codon, as compared to variant 1. The encoded isoform (3) has a shorter N-terminus, as compared to isoform 1.