GREM2 (NM_022469) Human Untagged Clone

CAT#: SC127022

GREM2 (untagged)-Human gremlin 2 (GREM2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GREM2
• Synonyms: CKTSF1B2; DAND3; PRDC; STHAG9
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127022 sequence for NM_022469 edited (data generated by NextGen Sequencing)
  ATGTTCTGGAAGCTTTCCCTGTCCTTGTTCCTGGTGGCGGTGCTGGTGAAGGTGGCGGAA
  GCCCGGAAGAACCGGCCGGCGGGCGCCATCCCCTCGCCTTACAAGGACGGCAGCAGCAAC
  AACTCGGAGAGATGGCAGCACCAGATCAAGGAGGTGCTGGCCTCCAGCCAGGAGGCCCTG
  GTGGTCACCGAGCGCAAGTACCTCAAGAGTGACTGGTGCAAGACGCAGCCGCTGCGGCAG
  ACGGTGAGCGAGGAGGGCTGCCGGAGCCGCACCATCCTCAACCGCTTCTGCTACGGCCAG
  TGCAACTCCTTCTACATCCCGCGGCACGTGAAGAAGGAGGAGGAGTCCTTCCAGTCCTGC
  GCCTTCTGCAAGCCCCAGCGCGTCACCTCCGTCCTCGTGGAGCTCGAGTGCCCCGGCCTG
  GACCCACCCTTCCGACTCAAGAAAATCCAGAAGGTGAAGCAGTGCCGGTGCATGTCCGTG
  AACCTGAGCGACTCGGACAAGCAGTGA
  
  Clone variation with respect to NM_022469.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022469 unedited
  AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTCTCAAAAAAAAAAAGAA
  GAAGAAAAAGAAAAGAAAAGAAAAATGAGAGCACTCAGAGCTGAGTCCACGTCAGGGAGC
  AGGCAGACGCCTTGCAGCCATCTCACTAGTCTGGGCTTTGAAGATTGCTGTTGGATGTTC
  TGGAAGCTTTCCCTGTCCTTGTTCCTGGTGGCGGTGCTGGTGAAGGTGGCGGAAGCCCGG
  AAGAACCGGCCGGCGGGCGCCATCCCCTCGCCTTACAAGGACGGCAGCAGCAACAACTCG
  GAGAGATGGCAGCACCAGATCAAGGAGGTGCTGGCCTCCAGCCAGGAGGCCCTGGTGGTC
  ACCGAGCGCAAGTACCTCAAGAGTGACTGGTGCAAGACGCAGCCGCTGCGGCAGACGGTG
  AGCGAGGAGGGCTGCCGGAGCCGCACCATCCTCAACCGCTTCTGCTACGGCCAGTGCAAC
  TCCTTCTACATCCCGCGGCACGTGAAGAAGGAGGAGGAGTCCTTCCAGTCCTGCGCCTTC
  TGCAAGCCCCAGCGCGTCACCTCCGTCCTCGTGGAGCTCGAGTGCCCCGGCCTGGACCCA
  CCCTTCCGACTCAAGAAAATCCAGAAGGTGAAGCAGTGCCGGTGCATGTCCGTGAACCTG
  AGCGACTCGGACAAGCAGTGAGCGCCGGGTCCGACGCAGCTCATCCCGCGCGCGCCCCGT
  CGCTGGGTGGCGCCGNCGTCGACTNTGTTCCTGACCTACGAGCCCACTGTCACGCTGGCT
  GGTGNNTCCCCCTCAGCAGCAGCACTTCTCTTAGGCTGACGGTGTCCTTGTACAGACGTG
  GATCGCAGGGNAGCTTTGCTGATGTGTTCTGACCGACCCGNTCCCACTGTGCCCCTAACC
  AGCGGGGATCAGCCCGAGGAATGCTGAAACACACCGCCCCAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_022469
• ORF Size: 507 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_022469.3, NP_071914.3
• RefSeq Size: 4199
• RefSeq ORF: 507
• Locus ID: 64388
• Domains: DAN, CT
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008]