Phosphatidic acid phosphatase type 2B (PPAP2B) (NM_177414) Human Untagged Clone

CAT#: SC127023

PPAP2B (untagged)-Human phosphatidic acid phosphatase type 2B (PPAP2B), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPAP2B
• Synonyms: Dri42; LPP3; MGC15306; PAP-2b; PAP2-b; PAP2-beta; VCIP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127023 sequence for NM_177414 edited (data generated by NextGen Sequencing)
  ATGCAAAACTACAAGTACGACAAAGCGATCGTCCCGGAGAGCAAGAACGGCGGCAGCCCG
  GCGCTCAACAACAACCCGAGGAGGAGCGGCAGCAAGCGGGTGCTGCTCATCTGCCTCGAC
  CTCTTCTGCCTCTTCATGGCGGGCCTCCCCTTCCTCATCATCGAGACAAGCACCATCAAG
  CCTTACCACCGAGGGTTTTACTGCAATGATGAGAGCATCAAGTACCCACTGAAAACTGGT
  GAGACAATAAATGACGCTGTGCTCTGTGCCGTGGGGATCGTCATTGCCATCCTCGCGATC
  ATCACGGGGGAATTCTACCGGATCTATTACCTGAAGAAGTCGCGGTCGACGATTCAGAAC
  CCCTACGTGGCAGCACTCTATAAGCAAGTGGGCTGCTTCCTCTTTGGCTGTGCCATCAGC
  CAGTCTTTCACAGACATTGCCAAAGTGTCCATAGGGCGCCTGCGTCCTCACTTCTTGAGT
  GTCTGCAACCCTGATTTCAGCCAGATCAACTGCTCTGAAGGCTACATTCAGAACTACAGA
  TGCAGAGGTGATGACAGCAAAGTCCAGGAAGCCAGGAAGTCCTTCTTCTCTGGCCATGCC
  TCCTTCTCCATGTACACTATGCTGTATTTGGTGCTATACCTGCAGGCCCGCTTCACTTGG
  CGAGGAGCCCGCCTGCTCCGGCCCCTCCTGCAGTTCACCTTGATCATGATGGCCTTCTAC
  ACGGGACTGTCTCGCGTATCAGACCACAAGCACCATCCCAGTGATGTTCTGGCAGGATTT
  GCTCAAGGAGCCCTGGTGGCCTGCTGCATAGTTTTCTTCGTGTCTGACCTCTTCAAGACT
  AAGACGACGCTCTCCCTGCCTGCCCCTGCTATCCGGAAGGAAATCCTTTCACCTGTGGAC
  ATTATTGACAGGAACAATCACCACAACATGATGTAG
  
  Clone variation with respect to NM_177414.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_177414 unedited
  TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTGCACTCTAGCCG
  CCGCGCCCGGAGCCGGGGCCGACCCGCCACTATCCGCAGCAGCCTCGGCCAGGAGGCGAC
  CCGGGCGCCTGGGTGTGTGGCTGCTGTTGCGGGACGTCTTCGCGGGGCGGGAGGCTCGCG
  CCGCANCCAGCGCCATGCAAAACTACAAGTACGACAAAGCGATCGTCCCGGAGAGCAAGA
  ACGGCGGCAGCCCGGCGCTCAACAACAACCCGAGGAGGAGCGGCAGCAAGCGGGTGCTGC
  TCATCTGCCTCGACCTCTTCTGCCTCTTCATGGCGGGCCTCCCCTTCCTCATCATCGAGA
  CAAGCACCATCAAGCCTTACCACCGAGGGTTTTACTGCAATGATGAGAGCATCAAGTACC
  CACTGAAAACTGGTGAGACAATAAATGACGCTGTGCTCTGTGCCGTGGGGATCGTCATTG
  CCATCCTCGCGATCATCACGGGGGAATTCTACCGGATCTATTACCTGAAGAAGTCGCGGT
  CGACGATTCAGAACCCCTACGTGGCAGCACTCTATAAGCAAGTGGGCTGCTTCCTCTTTG
  GCTGTGCCATCAGCCAGTCTTTCACAGACATTGCCAAAGTGTCCATAGGGCGCCTGCGTC
  CTCACTTCTTGAGTGTCTGCAACCCTGATTTCAGCCAGATCAACTGCTCTGAAGGCTACA
  TTCAGAACTACAGATGCAGAGGTGATGACAGCNAAGTCCAGGAAGCCAGGAGTTCTTCTT
  CTCTGGCATGCCTCCTTCTCATGTACACTATGCTGTATTTGGTGCTATACTGCAGNCCGC
  TCACTTGCGAGGAGCCGCTGTTCGNCCCTCTGCAGTCACTGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_177414 unedited
  TACCGAAGCCGCAATTTANAGTCGAGTTTTTTTTCTTTTTTTTTCCTTATTAGTTGTGTT
  ACGAGCTTTTATTTAAAAAGCACATTTAATACAAGTATAGTTTCGCAGATACAAGTTTTC
  ACTTTGTATGCTACAAAAGTCTTTGAATATTATTCTCTTTACAAAATGGAACCTTACAAA
  AATACTGACAATTTAATGTTTTTATACAGTTTTCTCTAGTTGCAGTTATTTCATTATAAA
  ACAATGTCTACCACAGAACTATGATATTTTAGTTGATATTTAAAAAAATTAACTCAATGC
  TTTTTTAAGCAGCTAATGTAAATAACACAGGTCGAGACACAGTTTATAATCATAGTGGAT
  ATAGCTAAATTGTTTCAGAAATAATATCTTACATAGTTAACTTTTAATGTTTTATACATT
  ATTTATATAATATTTATATATAAAAATCATAGCTTGCTATAAGTTGAAATGAAAGGACGG
  ATTCTGTAGTAAGGATGTGCATGTGGTTGATCCATATGGTTACATTTAACCCTTTGAAAG
  GTCTGCATCCAAGATCTAAACGCATTTCTTCCTTCCTCCTTTCCTCAAAGGTTCAGTAGA
  AGGGGTCCCTGTCTATCACCTAGAGTGGGACCTTGCATGGAAGGACACTTACGGATAGAG
  GATGAGGAAAACTCTCTACCGAGATTTAACCCATATGTNTCTGCCCAGCAGAACCTACCA
  AGAACTGCCCTNAGGCTCAACCCCAAAGACATAGTGCTTTACACAGCAAGAGCAACTCCT
  ACAAAGACCCTAGCTCTGTCATCCTGAAGGGTAACCTCTCATGCATGAGACTGCCCGCTC
  TTCTGGCTCCTTTCTGATTGCACAGCTAAAAGGTTGTTCGATTTCTTTTTGCCCCTTACC
  CTCCATTTGTTGACAAAAGCTGCTTCCGTCACCTGTTGCAGACATGCCTGCTCATCCCAG
  NCCTACAGAAATCTGTGGCCCCAACAAGATTCAAGGAAAAGCCTAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_177414
• ORF Size: 936 bp
• Insert Size: 2930
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_177414.1, NP_803133.1
• RefSeq Size: 3243
• RefSeq ORF: 936
• Locus ID: 8613
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Ether lipid metabolism, Fc gamma R-mediated phagocytosis, Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, Sphingolipid metabolism
• Gene Summary: The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells. [provided by RefSeq, Mar 2010]
  Transcript Variant: This variant (2) lacks an internal segment within the 5' UTR, as compared to variant 1. Both variants encode the same protein.