GLEPP1 (PTPRO) (NM_002848) Human Untagged Clone

CAT#: SC127070

PTPRO (untagged)-Human protein tyrosine phosphatase, receptor type, O (PTPRO), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRO
• Synonyms: GLEPP1; NPHS6; PTP-OC; PTP-U2; PTPROT; PTPU2; R-PTP-O
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_002848, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGCACCTGCCCACGGGGATACACGGCGCCCGCCGCCTCCTGCCTCTGCTCTGGCTCTTTGTGCTGT
  TCAAGAATGCTACAGCTTTCCATGTAACTGTCCAAGATGATAATAACATCGTTGTCTCATTAGAAGCTTC
  AGACGTCATCAGTCCAGCATCTGTGTATGTTGTGAAGATAACTGGTGAATCCAAAAATTATTTCTTCGAA
  TTTGAGGAATTCAACAGCACTTTGCCTCCTCCTGTTATTTTCAAGGCCAGTTATCATGGCCTTTATTATA
  TAATCACTCTGGTAGTGGTAAATGGAAATGTGGTGACCAAGCCATCCAGATCAATCACTGTGTTAACAAA
  ACCTCTACCTGTAACCAGTGTTTCCATATATGACTATAAACCTTCTCCTGAAACAGGAGTCCTGTTTGAA
  ATACATTATCCAGAAAAATATAACGTTTTCACAAGAGTGAACATTAGCTACTGGGAAGGTAAAGACTTCC
  GGACAATGCTATATAAAGATTTCTTTAAGGGAAAAACAGTATTTAATCACTGGCTGCCAGGAATGTGTTA
  TAGTAATATCACCTTTCAGCTGGTATCTGAGGCAACTTTTAATAAAAGTACCCTTGTTGAGTACAGTGGT
  GTCAGTCACGAACCCAAACAGCACAGAACTGCCCCTTATCCACCTCAAAATATTTCCGTTCGTATCGTAA
  ACTTGAACAAAAACAACTGGGAAGAACAGAGTGGCAATTTCCCAGAAGAATCCTTCATGAGATCACAAGA
  TACAATAGGAAAAGAAAAACTCTTCCATTTTACAGAAGAAACCCCTGAAATTCCCTCGGGCAACATTTCT
  TCCGGTTGGCCTGATTTTAATAGCAGTGACTATGAAACTACGTCTCAGCCATATTGGTGGGACAGTGCAT
  CTGCAGCTCCTGAAAGTGAAGATGAATTTGTCAGCGTACTTCCCATGGAATACGAAAATAACAGTACACT
  CAGTGAGACAGAGAAGTCAACATCAGGCTCTTTCTCCTTTTTCCCTGTGCAAATGATATTGACCTGGTTA
  CCACCCAAACCACCCACTGCTTTTGATGGGTTCCATATCCATATTGAACGAGAAGAGAACTTTACTGAAT
  ATTTGATGGTGGATGAAGAAGCACATGAATTTGTTGCAGAACTGAAGGAACCTGGGAAATATAAGTTATC
  TGTGACAACCTTTAGTTCCTCAGGATCTTGTGAAACTCGAAAAAGTCAGTCAGCAAAATCACTCAGCTTT
  TATATCAGTCCTTCAGGAGAGTGGATTGAAGAACTGACCGAGAAGCCGCAGCACGTGAGTGTCCACGTTT
  TAAGCTCAACCACTGCCTTGATGTCCTGGACATCTTCCCAAGAGAACTACAACAGCACCATTGTGTCTGT
  GGTGTCGCTGACCTGCCAGAAACAAAAGGAGAGCCAGAGGCTTGAAAAGCAGTACTGCACTCAGGTGAAC
  TCAAGCAAACCTATTATTGAAAATCTGGTTCCTGGTGCCCAGTACCAGGTTGTAATATACCTAAGGAAAG
  GCCCTTTGATTGGACCACCTTCAGATCCTGTGACATTTGCTATTGTTCCCACAGGAATAAAGGATTTAAT
  GCTCTATCCTTTGGGTCCTACGGCCGTGGTTCTGAGCTGGACCAGACCTTATTTAGGCGTGTTCAGAAAA
  TACGTGGTTGAAATGTTTTATTTCAACCCTGCTACAATGACATCAGAGTGGACCACCTACTATGAAATAG
  CAGCAACTGTTTCCTTAACTGCATCCGTGAGAATAGCTAATCTGCTGCCAGCATGGTACTACAACTTCCG
  GGTTACCATGGTGACGTGGGGAGATCCAGAATTGAGCTGCTGTGACAGCTCTACCATCAGCTTCATAACA
  GCCCCAGTGGCTCCGGAAATCACTTCTGTGGAATATTTCAACAGTCTGTTATATATCAGTTGGACATATG
  GGGATGATACAACGGACTTGTCCCATTCTAGAATGCTTCACTGGATGGTGGTTGCAGAAGGAAAAAAGAA
  AATTAAAAAGAGTGTAACACGCAATGTCATGACTGCAATTCTCAGCTTGCCTCCAGGCGACATCTATAAC
  CTCTCAGTAACTGCTTGTACTGAAAGAGGAAGTAATACCTCCATGCTCCGCCTTGTCAAGCTAGAACCAG
  CTCCACCCAAATCACTCTTCGCAGTGAACAAAACCCAGACTTCAGTGACTTTGCTGTGGGTGGAAGAGGG
  AGTAGCTGATTTCTTTGAAGTTTTCTGTCAACAAGTTGGCTCCAGTCAGAAAACCAAACTTCAGGAACCA
  GTTGCTGTTTCTTCCCATGTCGTGACCATCTCCAGCCTTCTTCCTGCCACTGCCTACAATTGTAGTGTCA
  CCAGCTTTAGCCATGACAGCCCCAGTGTCCCTACGTTCATAGCCGTCTCAACAATGGTTACAGAGATGAA
  TCCCAATGTGGTAGTGATCTCCGTGCTGGCCATCCTTAGCACACTTTTAATTGGACTGTTGCTTGTTACC
  CTCATTATTCTTAGGAAAAAGCATCTGCAGATGGCTAGGGAGTGTGGAGCTGGTACATTTGTCAATTTTG
  CATCCTTAGAGAGGGATGGAAAGCTTCCATACAACTGGAGTAAAAATGGTTTAAAGAAGAGGAAACTGAC
  AAACCCGGTTCAACTGGATGACTTTGATGCCTATATTAAGGATATGGCCAAAGACTCTGACTATAAATTT
  TCTCTTCAGTTTGAGGAGTTGAAATTGATTGGACTGGATATCCCACACTTTGCTGCAGATCTTCCACTGA
  ATCGATGTAAAAACCGTTACACAAACATCCTACCATATGACTTCAGCCGTGTGAGATTAGTCTCCATGAA
  TGAAGAGGAAGGTGCAGACTACATCAATGCCAACTATATTCCTGGATACAACTCACCCCAGGAGTATATT
  GCCACCCAGGGGCCACTGCCTGAAACCAGAAATGACTTCTGGAAGATGGTCCTGCAACAAAAGTCTCAGA
  TTATTGTCATGCTCACTCAGTGTAATGAGAAAAGGAGGGTGAAATGTGACCATTACTGGCCATTCACGGA
  AGAACCTATAGCCTATGGAGACATCACTGTGGAGATGATTTCAGAGGAAGAGCAGGACGACTGGGCCTGT
  AGACACTTCCGGATCAACTATGCTGACGAGATGCAGGATGTGATGCATTTTAACTACACTGCATGGCCTG
  ATCATGGTGTGCCCACAGCAAATGCTGCAGAAAGTATCCTGCAGTTTGTACACATGGTCCGACAGCAAGC
  TACCAAGAGCAAAGGTCCCATGATCATTCACTGCAGTGCTGGCGTGGGACGGACAGGAACATTCATTGCC
  CTGGACAGGCTCTTGCAGCACATTCGGGATCATGAGTTTGTTGACATCTTAGGGCTGGTGTCAGAAATGA
  GGTCATACCGGATGTCTATGGTACAGACAGAGGAGCAGTACATTTTTATCCATCAGTGTGTGCAACTGAT
  GTGGATGAAGAAGAAGCAGCAGTTCTGCATCAGTGATGTCATATACGAGAATGTTAGCAAGTCCTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002848 unedited
  TACGACTCCTATAGGCGGCCCGCGAATTCGCACGAGGCCTCGTGCCGAATTCGGCACGAG
  GATTTTATGGGTCGGCAGCCAGAGTGAGAGTGTCCCTGCTGCCAGAGGACTACGGCGGGC
  TGGGCGCGGGGTCCCCGCCTCTCGCTCACCACACAGACCCCGCGCCTCCTCTGGCAGCCG
  CGGTGGTGGCGGCGGCAGAGCCTCGCCCACTCCAATCCCCACCCTCTCCATCCTTAGTCA
  TTAAAGAACAGCAGCGCCTGGCACGTTCTTGGAGGACCCCGGGCGCAGAGGAGGAAAGGG
  AGCAGGCGCAGGGGGACTGGAAAGGCAGCATGCGCTCGCCAGGAGCAACCTCGGCGCCCA
  GGGTCTGAGGCTGCAGCCCCAGTTCGCCATTGTGAGCCGCCGCCGGGGGAGTCCGCTAGC
  GCAGCCGTGCCCCCGAGTCCCCGTCCGCGCAGCGATGGGGCACCTGCCCACGGGGATACA
  CGGCGCCCGCCGCCTCCTGCCTCTGCTCTGGCTCTTTGTGCTGTTCAAGAATGCTACAGC
  TTTCCATGTAACTGTCCAAGATGATAATAACATCGTTGTCTCATTAGAAGCTTCAGACGT
  CATCAGTCCAGCATCTGTGTATGTTGTGAAGATAACTGGTGAATCCAANAATTATTTCTT
  CGAATTTGAGGAATTCAACAGCCCTTTGCCTCCTNCTGTTATTTTCAAGGCCAGTTATCA
  TGGCCTTTATATATAATCACTCTGGTAGTGGTAATGGAAATGTGGTGACCAAGCATCCAG
  ATCAATCACTGTGTTAACAAACCTCTACCTGAACCAGTGTTTCCATAATGACTATAAACC
  TCTCCTGAACAAGAGTCCTGTTTGAAATACATTATCCAGAAATATTACGGTTTCCAAGAG
  TGACTTTACTCTGGGAAGGTAAGACTCCA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002848 unedited
  NTTCTTGNCCGCGGCCGCATTCTANATCGAGTTTTTTTTTTTTTTTTTTTTCCTGTCATC
  ACCTCTTATTTATCAGGAAGTGACACAAAGTAACAGGCTTCACAATGCCATCAATGTCAT
  TTTGACAGCATTCATGTCACAATACACAATCATGTACTGTAATTATACAAAATCCAAAGA
  ATAAAATGTTACTAGTTACACTCGTTAAAATGAAACTGACAACCAAAAGAATAACAAAAC
  AAAAAGAAATCTCTGTCAGAATCCATAGAGACATTTGACAATATTACAAAAAAAAGTAGT
  CAAATAATTGTCCCAGCATGCTGCAGTTCATTGCCATAACTTCATAAATTCCCAGCTCTT
  TGGGGGAAAGAAAGTGCGTTTTCACAGCCTATATAGTTCTTAAAGAAATAGCTCTCACAT
  GTATGCAGGTCAACAGAACAAGGAATGCAAAGTCTAGGCACCACGATTGCTCAGACAGCA
  ACAGAGTTCAAAGAGTCCAACTTGACACTCTTCTGAACCAGATGTGGTTTCTTGAGAAAG
  AACTTGGACAGTAACATTAGTCCAAAAGGGCCAAGGAAGAAACACCAACTGTTAATAAGG
  AAGAAAACCATCAAGAACTAGAACAGTTAAGACAATTTTTTTTCTACTCTACTTTGAAGC
  TGAATTATAGCTTGAATAGTAAAAGATACACAGGTGATCTGTGGGTAGAACCCCTTTCNC
  CCTGACCACCCTTCCCAATCCAGATCCGGGAATTGTTGAATACAGAAAGGGCCTGGCTCA
  ATTTCTTTGAAGGAAAAGACCATTTCTTCTGGGGTGGCCATGCCCTCTTTTAATAAGAAG
  TATAATCGGATGCTAACAAGCCTGTTCCTTCCTGGTTTATGGGCCTGTGAACAGGGGAGG
  CAAAAAACATTCACTTTTTGGTAAAATTCACCCCCCCACAAATTTGTGCCTCGAAAACAA
  ACCCTTAAAATAAAAACCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002848
• Insert Size: 5750 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002848.2, NP_002839.1
• RefSeq Size: 6295 bp
• RefSeq ORF: 3567 bp
• Locus ID: 5800
• Cytogenetics: 12p13-p12
• Domains: Y_phosphatase, PTPc_motif, FN3
• Protein Families: Phosphatase, Transmembrane
• Gene Summary: 'This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011]'
  Transcript Variant: This variant (2) lacks an exon in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.