GLEPP1 (PTPRO) (NM_002848) Human Untagged Clone

CAT#: SC127070

PTPRO (untagged)-Human protein tyrosine phosphatase, receptor type, O (PTPRO), transcript variant 2


  "NM_002848" in other vectors (4)

Reconstitution Protocol

USD 2,400.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PTPRO
Synonyms GLEPP1; NPHS6; PTP-OC; PTP-U2; PTPROT; PTPU2; R-PTP-O
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_002848, the custom clone sequence may differ by one or more nucleotides


ATGGGGCACCTGCCCACGGGGATACACGGCGCCCGCCGCCTCCTGCCTCTGCTCTGGCTCTTTGTGCTGT
TCAAGAATGCTACAGCTTTCCATGTAACTGTCCAAGATGATAATAACATCGTTGTCTCATTAGAAGCTTC
AGACGTCATCAGTCCAGCATCTGTGTATGTTGTGAAGATAACTGGTGAATCCAAAAATTATTTCTTCGAA
TTTGAGGAATTCAACAGCACTTTGCCTCCTCCTGTTATTTTCAAGGCCAGTTATCATGGCCTTTATTATA
TAATCACTCTGGTAGTGGTAAATGGAAATGTGGTGACCAAGCCATCCAGATCAATCACTGTGTTAACAAA
ACCTCTACCTGTAACCAGTGTTTCCATATATGACTATAAACCTTCTCCTGAAACAGGAGTCCTGTTTGAA
ATACATTATCCAGAAAAATATAACGTTTTCACAAGAGTGAACATTAGCTACTGGGAAGGTAAAGACTTCC
GGACAATGCTATATAAAGATTTCTTTAAGGGAAAAACAGTATTTAATCACTGGCTGCCAGGAATGTGTTA
TAGTAATATCACCTTTCAGCTGGTATCTGAGGCAACTTTTAATAAAAGTACCCTTGTTGAGTACAGTGGT
GTCAGTCACGAACCCAAACAGCACAGAACTGCCCCTTATCCACCTCAAAATATTTCCGTTCGTATCGTAA
ACTTGAACAAAAACAACTGGGAAGAACAGAGTGGCAATTTCCCAGAAGAATCCTTCATGAGATCACAAGA
TACAATAGGAAAAGAAAAACTCTTCCATTTTACAGAAGAAACCCCTGAAATTCCCTCGGGCAACATTTCT
TCCGGTTGGCCTGATTTTAATAGCAGTGACTATGAAACTACGTCTCAGCCATATTGGTGGGACAGTGCAT
CTGCAGCTCCTGAAAGTGAAGATGAATTTGTCAGCGTACTTCCCATGGAATACGAAAATAACAGTACACT
CAGTGAGACAGAGAAGTCAACATCAGGCTCTTTCTCCTTTTTCCCTGTGCAAATGATATTGACCTGGTTA
CCACCCAAACCACCCACTGCTTTTGATGGGTTCCATATCCATATTGAACGAGAAGAGAACTTTACTGAAT
ATTTGATGGTGGATGAAGAAGCACATGAATTTGTTGCAGAACTGAAGGAACCTGGGAAATATAAGTTATC
TGTGACAACCTTTAGTTCCTCAGGATCTTGTGAAACTCGAAAAAGTCAGTCAGCAAAATCACTCAGCTTT
TATATCAGTCCTTCAGGAGAGTGGATTGAAGAACTGACCGAGAAGCCGCAGCACGTGAGTGTCCACGTTT
TAAGCTCAACCACTGCCTTGATGTCCTGGACATCTTCCCAAGAGAACTACAACAGCACCATTGTGTCTGT
GGTGTCGCTGACCTGCCAGAAACAAAAGGAGAGCCAGAGGCTTGAAAAGCAGTACTGCACTCAGGTGAAC
TCAAGCAAACCTATTATTGAAAATCTGGTTCCTGGTGCCCAGTACCAGGTTGTAATATACCTAAGGAAAG
GCCCTTTGATTGGACCACCTTCAGATCCTGTGACATTTGCTATTGTTCCCACAGGAATAAAGGATTTAAT
GCTCTATCCTTTGGGTCCTACGGCCGTGGTTCTGAGCTGGACCAGACCTTATTTAGGCGTGTTCAGAAAA
TACGTGGTTGAAATGTTTTATTTCAACCCTGCTACAATGACATCAGAGTGGACCACCTACTATGAAATAG
CAGCAACTGTTTCCTTAACTGCATCCGTGAGAATAGCTAATCTGCTGCCAGCATGGTACTACAACTTCCG
GGTTACCATGGTGACGTGGGGAGATCCAGAATTGAGCTGCTGTGACAGCTCTACCATCAGCTTCATAACA
GCCCCAGTGGCTCCGGAAATCACTTCTGTGGAATATTTCAACAGTCTGTTATATATCAGTTGGACATATG
GGGATGATACAACGGACTTGTCCCATTCTAGAATGCTTCACTGGATGGTGGTTGCAGAAGGAAAAAAGAA
AATTAAAAAGAGTGTAACACGCAATGTCATGACTGCAATTCTCAGCTTGCCTCCAGGCGACATCTATAAC
CTCTCAGTAACTGCTTGTACTGAAAGAGGAAGTAATACCTCCATGCTCCGCCTTGTCAAGCTAGAACCAG
CTCCACCCAAATCACTCTTCGCAGTGAACAAAACCCAGACTTCAGTGACTTTGCTGTGGGTGGAAGAGGG
AGTAGCTGATTTCTTTGAAGTTTTCTGTCAACAAGTTGGCTCCAGTCAGAAAACCAAACTTCAGGAACCA
GTTGCTGTTTCTTCCCATGTCGTGACCATCTCCAGCCTTCTTCCTGCCACTGCCTACAATTGTAGTGTCA
CCAGCTTTAGCCATGACAGCCCCAGTGTCCCTACGTTCATAGCCGTCTCAACAATGGTTACAGAGATGAA
TCCCAATGTGGTAGTGATCTCCGTGCTGGCCATCCTTAGCACACTTTTAATTGGACTGTTGCTTGTTACC
CTCATTATTCTTAGGAAAAAGCATCTGCAGATGGCTAGGGAGTGTGGAGCTGGTACATTTGTCAATTTTG
CATCCTTAGAGAGGGATGGAAAGCTTCCATACAACTGGAGTAAAAATGGTTTAAAGAAGAGGAAACTGAC
AAACCCGGTTCAACTGGATGACTTTGATGCCTATATTAAGGATATGGCCAAAGACTCTGACTATAAATTT
TCTCTTCAGTTTGAGGAGTTGAAATTGATTGGACTGGATATCCCACACTTTGCTGCAGATCTTCCACTGA
ATCGATGTAAAAACCGTTACACAAACATCCTACCATATGACTTCAGCCGTGTGAGATTAGTCTCCATGAA
TGAAGAGGAAGGTGCAGACTACATCAATGCCAACTATATTCCTGGATACAACTCACCCCAGGAGTATATT
GCCACCCAGGGGCCACTGCCTGAAACCAGAAATGACTTCTGGAAGATGGTCCTGCAACAAAAGTCTCAGA
TTATTGTCATGCTCACTCAGTGTAATGAGAAAAGGAGGGTGAAATGTGACCATTACTGGCCATTCACGGA
AGAACCTATAGCCTATGGAGACATCACTGTGGAGATGATTTCAGAGGAAGAGCAGGACGACTGGGCCTGT
AGACACTTCCGGATCAACTATGCTGACGAGATGCAGGATGTGATGCATTTTAACTACACTGCATGGCCTG
ATCATGGTGTGCCCACAGCAAATGCTGCAGAAAGTATCCTGCAGTTTGTACACATGGTCCGACAGCAAGC
TACCAAGAGCAAAGGTCCCATGATCATTCACTGCAGTGCTGGCGTGGGACGGACAGGAACATTCATTGCC
CTGGACAGGCTCTTGCAGCACATTCGGGATCATGAGTTTGTTGACATCTTAGGGCTGGTGTCAGAAATGA
GGTCATACCGGATGTCTATGGTACAGACAGAGGAGCAGTACATTTTTATCCATCAGTGTGTGCAACTGAT
GTGGATGAAGAAGAAGCAGCAGTTCTGCATCAGTGATGTCATATACGAGAATGTTAGCAAGTCCTAG


>OriGene 5' read for NM_002848 unedited
TACGACTCCTATAGGCGGCCCGCGAATTCGCACGAGGCCTCGTGCCGAATTCGGCACGAG
GATTTTATGGGTCGGCAGCCAGAGTGAGAGTGTCCCTGCTGCCAGAGGACTACGGCGGGC
TGGGCGCGGGGTCCCCGCCTCTCGCTCACCACACAGACCCCGCGCCTCCTCTGGCAGCCG
CGGTGGTGGCGGCGGCAGAGCCTCGCCCACTCCAATCCCCACCCTCTCCATCCTTAGTCA
TTAAAGAACAGCAGCGCCTGGCACGTTCTTGGAGGACCCCGGGCGCAGAGGAGGAAAGGG
AGCAGGCGCAGGGGGACTGGAAAGGCAGCATGCGCTCGCCAGGAGCAACCTCGGCGCCCA
GGGTCTGAGGCTGCAGCCCCAGTTCGCCATTGTGAGCCGCCGCCGGGGGAGTCCGCTAGC
GCAGCCGTGCCCCCGAGTCCCCGTCCGCGCAGCGATGGGGCACCTGCCCACGGGGATACA
CGGCGCCCGCCGCCTCCTGCCTCTGCTCTGGCTCTTTGTGCTGTTCAAGAATGCTACAGC
TTTCCATGTAACTGTCCAAGATGATAATAACATCGTTGTCTCATTAGAAGCTTCAGACGT
CATCAGTCCAGCATCTGTGTATGTTGTGAAGATAACTGGTGAATCCAANAATTATTTCTT
CGAATTTGAGGAATTCAACAGCCCTTTGCCTCCTNCTGTTATTTTCAAGGCCAGTTATCA
TGGCCTTTATATATAATCACTCTGGTAGTGGTAATGGAAATGTGGTGACCAAGCATCCAG
ATCAATCACTGTGTTAACAAACCTCTACCTGAACCAGTGTTTCCATAATGACTATAAACC
TCTCCTGAACAAGAGTCCTGTTTGAAATACATTATCCAGAAATATTACGGTTTCCAAGAG
TGACTTTACTCTGGGAAGGTAAGACTCCA
>OriGene 3' read for NM_002848 unedited
NTTCTTGNCCGCGGCCGCATTCTANATCGAGTTTTTTTTTTTTTTTTTTTTCCTGTCATC
ACCTCTTATTTATCAGGAAGTGACACAAAGTAACAGGCTTCACAATGCCATCAATGTCAT
TTTGACAGCATTCATGTCACAATACACAATCATGTACTGTAATTATACAAAATCCAAAGA
ATAAAATGTTACTAGTTACACTCGTTAAAATGAAACTGACAACCAAAAGAATAACAAAAC
AAAAAGAAATCTCTGTCAGAATCCATAGAGACATTTGACAATATTACAAAAAAAAGTAGT
CAAATAATTGTCCCAGCATGCTGCAGTTCATTGCCATAACTTCATAAATTCCCAGCTCTT
TGGGGGAAAGAAAGTGCGTTTTCACAGCCTATATAGTTCTTAAAGAAATAGCTCTCACAT
GTATGCAGGTCAACAGAACAAGGAATGCAAAGTCTAGGCACCACGATTGCTCAGACAGCA
ACAGAGTTCAAAGAGTCCAACTTGACACTCTTCTGAACCAGATGTGGTTTCTTGAGAAAG
AACTTGGACAGTAACATTAGTCCAAAAGGGCCAAGGAAGAAACACCAACTGTTAATAAGG
AAGAAAACCATCAAGAACTAGAACAGTTAAGACAATTTTTTTTCTACTCTACTTTGAAGC
TGAATTATAGCTTGAATAGTAAAAGATACACAGGTGATCTGTGGGTAGAACCCCTTTCNC
CCTGACCACCCTTCCCAATCCAGATCCGGGAATTGTTGAATACAGAAAGGGCCTGGCTCA
ATTTCTTTGAAGGAAAAGACCATTTCTTCTGGGGTGGCCATGCCCTCTTTTAATAAGAAG
TATAATCGGATGCTAACAAGCCTGTTCCTTCCTGGTTTATGGGCCTGTGAACAGGGGAGG
CAAAAAACATTCACTTTTTGGTAAAATTCACCCCCCCACAAATTTGTGCCTCGAAAACAA
ACCCTTAAAATAAAAACCT
Restriction Sites NotI-NotI     
ACCN NM_002848
Insert Size 5750 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002848.2, NP_002839.1
RefSeq Size 6295 bp
RefSeq ORF 3567 bp
Locus ID 5800
Cytogenetics 12p13-p12
Domains Y_phosphatase, PTPc_motif, FN3
Protein Families Phosphatase, Transmembrane
Gene Summary 'This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011]'
Transcript Variant: This variant (2) lacks an exon in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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