KCNH8 (NM_144633) Human Untagged Clone

CAT#: SC127343

KCNH8 (untagged)-Human potassium voltage-gated channel, subfamily H (eag-related), member 8 (KCNH8)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNH8
• Synonyms: ELK; ELK1; elk3; Kv12.1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_144633 edited
  ATGCCGGTTATGAAAGGATTACTGGCGCCGCAAAACACCTTCCTGGACACCATCGCCACC
  CGTTTTGACGGAACACATAGCAACTTCATCCTTGCCAATGCCCAGGTGGCTAAGGGTTTC
  CCCATAGTCTACTGTTCCGATGGCTTCTGCGAGCTTGCTGGATTTGCCCGAACTGAAGTC
  ATGCAGAAGAGTTGTAGCTGCAAGTTCTTATTTGGGGTTGAAACCAATGAGCAACTGATG
  CTTCAAATAGAAAAGTCACTGGAGGAGAAAACAGAATTCAAAGGAGAAATTATGTTCTAC
  AAGAAAAACGGGTCTCCATTTTGGTGCCTACTGGATATTGTTCCCATAAAGAATGAAAAA
  GGAGATGTAGTACTTTTTCTGGCCTCGTTCAAAGATATAACAGATACAAAAGTGAAGATT
  ACTCCAGAAGATAAAAAAGAAGACAAAGTCAAAGGAAGATCAAGAGCAGGGACCCACTTT
  GACTCAGCCCGGAGACGGAGTCGAGCAGTCCTTTATCACATCTCTGGGCACCTGCAAAGA
  AGAGAAAAGAACAAATTGAAAATAAATAACAATGTTTTTGTAGATAAACCAGCATTTCCG
  GAGTATAAAGTTTCTGATGCAAAAAAGTCCAAATTCATACTTCTGCATTTTAGCACTTTT
  AAAGCTGGCTGGGACTGGCTTATTTTGTTGGCAACGTTTTATGTTGCTGTGACTGTACCT
  TACAACGTTTGCTTTATTGGCAATGACGACCTGTCCACAACTCGGAGCACAACCGTCAGT
  GACATTGCAGTGGAGATTCTTTTTATTATAGATATTATTTTAAATTTCCGAACAACTTAT
  GTCAGCAAGTCTGGCCAAGTTATCTTTGAAGCAAGATCAATTTGCATCCACTATGTCACA
  ACCTGGTTCATCATTGATTTAATCGCTGCCCTGCCTTTTGATCTTCTGTATGCTTTCAAC
  GTCACAGTGGTGTCTCTCGTGCATCTTCTAAAGACAGTGCGCCTCTTGCGTCTTTTGCGT
  CTGCTGCAGAAGTTAGACCGCTATTCCCAACACAGTACTATCGTCCTGACTCTGCTCATG
  TCCATGTTTGCACTCCTTGCACACTGGATGGCGTGTATCTGGTACGTCATTGGAAAAATG
  GAGAGGGAAGACAACAGCCTTCTGAAGTGGGAAGTTGGTTGGCTTCATGAGTTGGGAAAG
  AGACTGGAATCTCCATACTATGGCAACAATACCTTGGGGGGCCCGTCGATCCGAAGTGCC
  TATATTGCCGCTCTGTACTTCACGCTGAGCAGCCTCACCAGCGTGGGTTTTGGGAACGTC
  TCTGCTAATACAGATGCAGAAAAGATCTTCTCCATCTGCACCATGCTGATTGGTGCCTTG
  ATGCACGCCTTGGTGTTTGGAAACGTGACAGCAATCATACAGAGGATGTACTCCAGATGG
  TCCCTCTATCACACTAGAACTAAGGATCTGAAAGATTTCATCCGTGTCCATCACTTGCCC
  CAACAACTCAAGCAGAGGATGCTCGAATATTTTCAAACAACCTGGTCAGTCAACAATGGA
  ATAGATTCAAATGAGCTTTTGAAAGACTTTCCAGATGAACTGCGTTCTGACATCACTATG
  CACTTGAACAAGGAGATCTTACAGTTGTCCCTTTTTGAATGTGCCAGCCGGGGCTGCCTC
  AGGTCTCTGTCTCTACACATCAAAACCTCTTTCTGTGCTCCGGGGGAGTATCTGCTGCGT
  CAAGGGGATGCTTTGCAGGCCATCTACTTTGTATGCTCGGGCTCCATGGAAGTTCTTAAA
  GACAGCATGGTGCTGGCTATTCTTGGGAAAGGGGATTTAATTGGAGCAAATCTATCAATT
  AAGGACCAAGTGATCAAGACCAATGCAGATGTAAAGGCTTTAACCTACTGTGATCTCCAG
  TGTATCATCCTCAAAGGACTCTTTGAAGTGCTAGACCTTTACCCAGAATATGCTCACAAA
  TTCGTGGAAGACATTCAGCATGACCTCACATACAACCTCCGAGAAGGTCATGAGAGTGAT
  GTGATATCAAGACTATCAAACAAATCTATGGTCTCACAGTCAGAGCCCAAGGGAAATGGC
  AACATCAACAAGCGACTCCCATCCATTGTGGAAGATGAGGAAGAGGAGGAGGAGGGGGAG
  GAAGAGGAGGCAGTCTCCCTCTCTCCCATCTGCACAAGGGGATCTTCTTCGCGCAACAAG
  AAGGTTGGAAGCAATAAAGCCTACCTGGGCTTAAGCTTAAAGCAACTGGCCTCGGGAACG
  GTGCCCTTTCACTCGCCTATCAGAGTCTCCAGGTCAAATTCCCCCAAAACCAAGCAGGAA
  ATTGACCCCCCCAACCATAATAAAAGGAAAGAGAAGAACTTGAAATTGCAACTTTCAACT
  TTGAATAATGCTGGACCCCCAGACCTCAGTCCAAGGATTGTTGATGGAATTGAAGATGGA
  AACAGCAGTGAAGAAAGTCAGACTTTTGATTTTGGCTCTGAACGAATCAGATCAGAGCCC
  AGAATTTCTCCTCCTCTTGGAGATCCAGAGATTGGAGCTGCTGTTCTCTTCATCAAAGCA
  GAGGAGACCAAGCAGCAGATAAACAAACTCAACAGTGAGGTAACAACATTGACTCAGGAA
  GTTTCTCAGTTGGGTAAAGACATGAGAAATGTGATCCAGCTTCTGGAAAACGTTCTGTCA
  CCTCAGCAGCCATCACGGTTTTGCTCTTTGCACAGCACCTCTGTGTGTCCCTCCAGGGAG
  AGCTTACAGACCAGAACGAGCTGGAGTGCACACCAGCCTTGCCTACACTTGCAAACAGGC
  GGGGCTGCTTATACCCAAGCACAACTTTGTAGCAGTAATATCACCTCAGACATTTGGAGT
  GTGGATCCCTCCTCTGTGGGGAGCAGCCCCCAACGAACTGGAGCTCATGAGCAAAATCCT
  GCAGACAGTGAACTTTATCATTCTCCAAGCCTTGATTATTCACCTTCCCACTACCAGGTT
  GTCCAAGAAGGTCATTTGCAATTTTTAAGGTGCATCTCTCCACATTCAGATTCTACGTTG
  ACGCCTCTGCAGTCCATTTCAGCAACTCTCTCATCTTCTGTCTGCTCCTCTTCGGAAACA
  TCTTTGCACCTAGTTCTCCCAAGCAGATCAGAGGAGGGCAGCTTCAGTCAGGGAACTGTG
  AGTTCCTTCAGTCTGGAAAACTTACCAGGATCTTGGAACCAGGAAGGAATGGCATCAGCT
  TCTACAAAACCTTTGGAGAACCTTCCACTGGAAGTTGTCACAAGCACAGCAGAAGTGAAA
  GATAACAAAGCCATAAATGTATGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_144633
• ORF Size: 3324 bp
• Insert Size: 5100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_144633.2, NP_653234.2
• RefSeq Size: 5106
• RefSeq ORF: 3324
• Locus ID: 131096
• Domains: cNMP, PAC, ion_trans
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• Gene Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. [provided by RefSeq, Jul 2008]