Cytohesin 3 (CYTH3) (NM_004227) Human Untagged Clone

CAT#: SC127412

CYTH3 (untagged)-Human cytohesin 3 (CYTH3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CYTH3
• Synonyms: ARNO3; cytohesin-3; GRP1; PSCD3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127412 sequence for NM_004227 edited (data generated by NextGen Sequencing)
  ATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAGACCTCTCATTAGAAGAG
  AGAGAAGAACTTCTAGACATTCGTCGAAGAAAAAAGGAACTTATTGATGACATTGAGAGG
  CTGAAATATGAAATTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAG
  AGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAAAGAAATTCAACATGGAT
  CCCAAAAAGGGAATTCAGTTTCTAATAGAAAATGACCTGCTACAGAGTTCCCCAGAAGAC
  GTCGCCCAGTTCCTTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTG
  GGTGAAAGGGATGAATTTAATATTAAAGTTCTTCAAGCCTTTGTTGAACTCCATGAGTTT
  GCTGATCTCAACCTTGTACAAGCCTTAAGGCAGTTCTTATGGAGCTTCAGGCTGCCCGGG
  GAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAAC
  CCCGGGGTCTTCCAGTCCACAGACACGTGCTACGTGCTGTCATTCGCCATCATCATGCTC
  AACACCAGCCTCCACAACCACAACGTGCGTGACAAGCCCACGGCAGAACGGTTCATCGCC
  ATGAACCGCGGCATCAACGAGGGCGGGGACCTCCCTGAGGAGCTGCTGAGGAATTTGTAT
  GAGAGCATTAAGAACGAGCCATTTAAGATCCCGGAGGACGACGGGAACGACCTGACCCAC
  ACCTTCTTCAACCCCGACCGCGAGGGCTGGCTCCTGAAGCTGGGAGGGCGTGTGAAGACC
  TGGAAGCGCCGGTGGTTCATCCTGACCGATAACTGCCTCTATTACTTTGAATACACAACA
  GATAAGGAGCCCAGGGGAATCATCCCGTTGGAAAACCTCAGCATCAGGGAGGTGGAGGAC
  CCCCGGAAACCCAACTGTTTTGAGCTCTACAATCCCAGCCACAAAGGGCAGGTCATCAAG
  GCCTGTAAGACGGAGGCCGACGGCCGCGTGGTAGAGGGGAACCATGTGGTGTACCGGATC
  TCAGCCCCGAGCCCGGAGGAGAAGGAGGAGTGGATGAAATCCATCAAAGCCAGTATCAGC
  AGAGATCCCTTCTATGACATGTTGGCAACGAGGAAACGAAGGATTGCCAATAAAAAATAG
  
  Clone variation with respect to NM_004227.3
  1032 t=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004227 unedited
  TATAGGGCGGCCGCGAATTCGGCACGAGGCTGCTGCCGGCCCCCGGCTCGCCGGCTGCGG
  GAGTGGCCTCAAGATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAGACCT
  CTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGAAAAAAGGAACTTATTGA
  TGACATTGAGAGGCTGAAATATGAAATTGCAGAGGTGATGACAGAGATCGACAATCTAAC
  TTCCGTAGAGGAGAGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAAAGAA
  ATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAAAATGACCTGCTACAGAG
  TTCCCCAGAAGACGTCGCCCAGTTCCTTTATAAAGGAGAAGGCCTAAATAAGACCGTCAT
  TGGGGACTACCTGGGTGAAAGGGATGAATTTAATATTAAAGTTCTTCAAGCCTTTGTTGA
  ACTCCATGAGTTTGCTGATCTCAACCTTGTACAAGCCTTAAGGCAGTTCTTATGGAGCTT
  CAGGCTGCCCGGNGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGCTA
  CTGCCTGTGCAACCCCGGNGTCTTCCAGTCCACAGACACGTGCTACGTGCTGTCATTCGC
  CATCATCATGCTCAACACCAGCCTCCACAACCACAACGTGCGTGACAAGCCCACGGCAGA
  ACGGTTCATCGCCATGAACCGCGGCATCAACGAGGGCGGNGACCTCCCCTGAGAGCTGCT
  GAAGAATTTGTATGAGAGCATTAGAACGAGCCATTTAGATCCCNGNAGACGACGGNACGA
  CCTGACCCACACTTCTTCACCCGACGCGAGGCTGGCTCTGAGCTGGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004227 unedited
  AAAGCTTGGACCGGCGGCCGCATNCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTAACA
  ATACATGTGATTTTTATTTAGTGAACACAGTATCTGCAAGAGCTCTGACAGCCATCCACC
  CTCCAATCTTACTTCACTTTACAACCAAGTATCAATAGAGGCTGTTCCTTCATGCGAGCT
  GTGGGAGTATATACATCATTGAATAACAGACACTCCAGAAATCAACAGATGTACATTATT
  TACATATTACTATATTTACCGCAAATAGAAATATTTTCTAAGAAAAAAAGTCAATTTGTG
  GTTTCTGGTCTACCACAGACCTAACTTCTCAGCAAAGCATATCTATGTAGATATCTGCGT
  TTGTAACTTTAAAAATAGGCATTGCTTTCTATGAAGCACTAAGTGCTGCTCCATCTATAA
  ATAGCTCCTATTTTCAGTTTGGTACCACATTAAACTGCCCCAAAATGTTCTGTGACCCCA
  AAGACACAAAGTTGCTGCTTATCTGGGTCCAGGGTCAGTACAATTAAACTCAAATATGAA
  CCAGGGCGGCCAGCAAGACAGGCTGGAAGGGCTGTGGCAGTCGCCGCCGCCTCCCCGCGG
  NGCTCCCCTCACTGCCTCCTGGCCTCTGTCTCTGGAAAAAAGTATCTTTGGCCAGAGTTG
  GGACTAACAATTCAAGCCCTGCGCTCANACNTCAGGNTGGNGAGGAAGAGGACTGTGATT
  GTGACGNCGCCTGCCCAGGGTGAGGGACAAANACAGATGTGTNCTGTTTCAGGNCCGTCC
  TGGTAGCGGCTGGCCCTGCGCAGTCACTGACCCAGATTTTCTGGACCAGCCTGCCTCAAG
  ATCAGCAGCATGATGGTCGACAGCCTCATGCTATACTGNNCTACACAGNCTGGAGCTAGC
  GATTCCTTTGACCACAANACCTGGAGTCTACTCAGCACCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004227
• ORF Size: 1200 bp
• Insert Size: 4470
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004227.3, NP_004218.1
• RefSeq Size: 4482
• RefSeq ORF: 1200
• Locus ID: 9265
• Domains: Sec7, PH
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longest isoform (a).