Neuroligin 4 (NLGN4X) (NM_020742) Human Untagged Clone

CAT#: SC127514

NLGN4X (untagged)-Human neuroligin 4, X-linked (NLGN4X), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NLGN4X
• Synonyms: ASPGX2; AUTSX2; HLNX; HNL4X; NLGN4
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127514 sequence for NM_020742 edited (data generated by NextGen Sequencing)
  ATGTCACGGCCCCAGGGACTGCTATGGCTTCCTTTGTTGTTCACCCCGGTCTGCGTCATG
  TTAAACTCCAATGTCCTCCTGTGGTTAACTGCTCTTGCCATCAAGTTCACCCTCATTGAC
  AGCCAAGCACAGTATCCAGTTGTCAACACAAATTATGGCAAAATCCGGGGCCTAAGAACA
  CCGTTACCCAATGAGATCTTGGGTCCAGTGGAGCAGTACTTAGGGGTCCCCTATGCCTCA
  CCCCCCACTGGAGAGAGGCGGTTTCAGCCCCCAGAACCCCCGTCCTCCTGGACTGGCATC
  CGAAATACTACTCAGTTTGCTGCTGTGTGCCCCCAGCACCTGGATGAGAGATCCTTACTG
  CATGACATGCTGCCCATCTGGTTTACCGCCAATTTGGATACTTTGATGACCTATGTTCAA
  GATCAAAATGAAGACTGCCTTTACTTAAACATCTACGTGCCCACGGAAGATGATATTCAT
  GATCAGAACAGTAAGAAGCCCGTCATGGTCTATATCCATGGGGGATCTTACATGGAGGGC
  ACCGGCAACATGATTGACGGCAGCATTTTGGCAAGCTACGGAAACGTCATCGTGATCACC
  ATTAACTACCGTCTGGGAATACTAGGGTTTTTAAGTACCGGTGACCAGGCAGCAAAAGGC
  AACTATGGGCTCCTGGATCAGATTCAAGCACTGCGGTGGATTGAGGAGAATGTGGGAGCC
  TTTGGCGGGGACCCCAAGAGAGTGACCATCTTTGGCTCGGGGGCTGGGGCCTCCTGTGTC
  AGCCTGTTGACCCTGTCCCACTACTCAGAAGGTCTCTTCCAGAAGGCCATCATTCAGAGC
  GGCACYGCCCTGTCCAGCTGGGCAGTGAACTACCAGCCGGCCAAGTACACTCGGATATTG
  GCAGACAAGGTCGGCTGCAACATGCTGGACACCACGGACATGGTAGAATGCCTGCGGAAC
  AAGAACTACAAGGAGCTCATCCAGCAGACCATCACCCCGGCCACCTACCACATAGCCTTC
  GGGCCGGTGATCGACGGCGACGTCATCCCAGACGACCCCCAGATCCTGATGGAGCAAGGC
  GAGTTCCTCAACTACGACATCATGCTGGGCGTCAACCAAGGGGAAGGCCTGAAGTTCGTG
  GACGGCATCGTGGATAACGAGGACGGTGTGACGCCCAACGACTTTGACTTCTCCGTGTCC
  AACTTCGTGGACAACCTTTACGGCTACCCTGAAGGGAAAGACACTTTGCGGGAGACTATC
  AAGTTCATGTACACAGACTGGGCCGATAAGGAAAACCCGGAGACGCGGCGGAAAACCCTG
  GTGGCTCTCTTTACTGACCAYCAGTGGGTGGCCCCCGCCGTGGCCACCGCCGACCTGCAC
  GCGCAGTACGGCTCCCCCACCTACTTCTATGCCTTCTATCATCACTGCCAAAGCGAAATG
  AAGCCCAGCTGGGCAGATTCGGCCCATGGYGATGAGGTCCCCTATGTCTTCGGCATCCCC
  ATGATCGGTCCCACMGAGCTCTTCAGTTGTAACTTTTCCAAGAACGACGTCATGCTCAGY
  GCCGTGGTSATGACCTACTGGACGAACTTCGCCAAAACTGGTGATCCAAATCAACCAGTT
  CCTCAGGATACCAAGTTCATTCAYACAAAACCCAACCGCTTTGAAGAAGTGGCCTGGTCC
  AAGTATAATCCCAAAGACCAGCTCTATCTGCATATTGGCTTGAAACCCAGAGTGAGAGAT
  CACTACCGGGCAACGAAAGTGGCTTTCTGGTTGGAACTCGTTCCTCATTTGCACAACTTG
  AACGAGATATTCCAGTATGTTTCAACAACCACAAAGGTTCCTCCACCAGACATGACATCA
  TTTCCCTATGGCACCCGGCGATCTCCCGCCAAGATATGGCCAACCACCAAACGCCCAGCA
  ATCACTCCTGCCAACAATCCCAAACACTCTAAGGACCCTCACAAAACAGGGCCYGAGGAC
  ACAACTGTCCTCATTGAAACCAAACGAGATTATTCCACCGAATTAAGTGTCACCATTGCC
  GTCGGGGCGTCGCTCCTCTTCCTCAACATCTTAGCTTTTGCGGCGCTGTACTACAAAAAG
  GACAAGAGGCGCCATGAGACTCACAGGCRCCCCAGTCCCCAGAGAAACACCACAAATGAT
  ATCRCTCACATCCAGAACGAAGAGATCATGTCTCTGCAGATGAAGCAGCTGGAACACGAT
  CACGAGTGTGAGTCGCTGCAGGCACACGACACRCTGAGGCTCACCTGCCCKCCAGACTAC
  ACCCTCACGCTGCGCCGGTCGCCAGATGACATCCCACTTATGACGCCAAACACCATCACC
  ATGATTCCAAACACACTGACGGGGATGCAGCCTTTGCACACTTTTAACACCTTCAGTGGA
  GGACAAAACAGTACAAATTTACCCCACGGACATTCCACCACTAGAGTATAG
  
  Clone variation with respect to NM_020742.2
  846 c=>y;1341 c=>y;1470 t=>y;1515 c=>m;1560 c=>y;1569 c=>s;1644 c=>y;1974 t=>y;2129 g=>r;2164 g=>r;2253 a=>r;2271 g=>k
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020742 unedited
  NGGGGGGGGGGGGNNNNNNNGGNTCNNCCNNNNTTTATTACACCCGCCCGTTGNCGCAAA
  GGGCGGTAGGCGTGTACGGTGGNGAGTCTATATAAGCAGAGCTCATTTAGGTGACACTAT
  AGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGGCACGAGGGGAGAGGAG
  GAAAAAAATATATATGTATCTGCAGTACAGGGAGAAGAAGGAGAGAAGCGGCCAGGGCTG
  GAGATGGTGAAGGCAGGAAGACTTCTGCAAACTGTGAGGCTGCCTTGGAGTTTTCATAAG
  AAATTGTCCCTGGAGGTGTTGGATGATCACAGCTTCCTTGGAGCATTGCAGTTGCTGGAA
  TCCAGTTTCAGGATTAAGGGAGGGCTGCCTCCTTGCAATGGGCTGCCAAGAAAACGGCTG
  TGCTTGTTCTTAACCTCAGGCTCTGTCTGTGATCAGTCTGAGAGTCTCTCCCAGGTCTAC
  TGCTCCCTGGAAAGCCCTATCTCTCTGCAGGCTCGCCTCTGGGCTTTGTCTCCTTGGAGC
  CACATCACTGGGACAGCTGTGGATGTGGATGCAGATTTGAACCATGTCACGGCCCCAGGG
  ACTGCTATGGCTTCCTTTGTTGTTCACCCCGGTCTGCGTCATGTTAAACTCCAATGTCCT
  CCTGTGGTTAACTGCTCTTGCCATCAAGTTCACCCTCATTGACAGCCAAGCACAGTATCC
  AGTTGTCAACACAAATTATGGCANAATCCGGGGCCTAAGAACACCGTTACCCAATGAGAT
  CTTGGGTCCAGTGGAGCAGTACTTAAGGGTCCCCTATGCCTCACCCCCACTGGAGAGAGG
  CGGTTTCAGCCCCCAAACCCCCGTCCTCCTGGACTGGCATNNCGAATACTACTCAGTTTG
  CTGCTGTGTGCCCCCAGCACCTGGATGAGAGACCTTACTGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020742 unedited
  CTATGTACGCGGCCGCATTTAGNATCGAGTTTTTTTTCTTTTTTTTTTCAATTTTTTTTC
  TTTTTTCTCTTTTTTATAGATAGCAAGTATATTTTTTCTCATAGAACTCTATGAAGATTC
  TATAACTTCTTTCCATGTAGAAATAAGATATCATTTAAGATGTACTAAAATCACTTTTGA
  TCATAATCCCCTGTAAAAGCTAAAGTTATTCACTTAACAGGAACTCTGTTTTTCCTTATT
  CAAATGTCACAAGCCTGACGCGTTACTGTACATATTGCTAGCAGGAGACAACTGGAAATA
  CTAAACAAATACTGGAATTCACATTACAGACAGACGAAACCAACATGGATGCCACACATA
  ACTTCCTTTGTAGTTTCACAGAGAGCCTATTTGTGGTTGCTCAGGTGGGGTCATACATTG
  CTTGCAGAAATGGCCTGATCATAGCTCTATGAAACAATGAATTCGGAATGAAATCTTACC
  ATGACACCTCTCTGTAGGAAAGAAATGTTGCTTCACGTGTGCTAAGTTGAGATAATAATA
  TTTCACATATTTATATACAGAGAATCACTCTCAAATTTAACCCAAGATAAGCAATAGGAT
  TTGGGGGTGACTTGTACACATTTCTAANAACACTTTTCTTTTTTCTAGAGGTCACTCTCA
  AACACTGATATATCACTATAGTTTGAGTGTAGGGATTCAGTAATCAAAGGTTGTTATTGC
  ANAAGAGCCCAGCAGCTGGACAATTTTTATGGGGAATGTCCACTTTAGCGNAGAGATTTA
  AGACTGGATTTCTAGAATAACCCANCATGGAGCCCGAGAAACATGATCTCAATATCTTTG
  GCTACTGGTNNCTGGNNTATGCAATATTTTTCAAAAAGTATCCATGCTACTATGTTNCCT
  TNCCANNCTATACACTCAAAACTTTCCTGANATGAGNAGAGAAATGAAAATGACAGCTGT
  TGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020742
• ORF Size: 2451 bp
• Insert Size: 5500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020742.2, NP_065793.1
• RefSeq Size: 5706
• RefSeq ORF: 2451
• Locus ID: 57502
• Domains: COesterase
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 3. Variants 1, 2, 3, and 4 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.