CTDSP2 (NM_005730) Human Untagged Clone

CAT#: SC128037

CTDSP2 (untagged)-Human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (CTDSP2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CTDSP2
• Synonyms: OS4; PSR2; SCP2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC128037 sequence for NM_005730 edited (data generated by NextGen Sequencing)
  ATGGAACACGGCTCCATCATCACCCAGGCGCGGAGGGAAGACGCCCTGGTGCTCACCAAG
  CAAGGCCTGGTCTCCAAGTCCTCTCCTAAGAAGCCTCGTGGACGTAACATCTTCAAGGCC
  CTTTTCTGCTGTTTTCGCGCCCAGCATGTTGGCCAGTCAAGTTCCTCCACTGAGCTCGCT
  GCGTATAAGGAGGAAGCAAACACCATTGCTAAGTCGGATCTGCTCCAGTGTCTCCAGTAC
  CAGTTCTACCAGATCCCAGGGACCTGCCTGCTCCCAGAGGTGACAGAGGAAGATCAAGGA
  AGGATCTGTGTGGTCATTGACCTCGATGAAACCCTTGTGCATAGCTCCTTTAAGCCAATC
  AACAATGCTGACTTCATAGTGCCTATAGAGATTGAGGGGACCACTCACCAGGTGTATGTG
  CTCAAGAGGCCTTATGTGGATGAGTTCCTGAGACGCATGGGGGAACTCTTTGAATGTGTT
  CTCTTCACTGCCAGCCTGGCCAAGTATGCCGACCCTGTGACAGACCTGCTGGACCGGTGT
  GGGGTGTTCCGGGCCCGCCTATTCCGTGAGTCTTGCGTGTTCCACCAGGGCTGCTACGTC
  AAGGACCTCAGCCGCCTGGGGAGGGACCTGAGAAAGACCCTCATCCTGGACAACTCGCCT
  GCTTCTTACATATTCCACCCCGAGAATGCAGTGCCTGTGCAGTCCTGGTTTGATGACATG
  GCAGACACTGAGTTGCTGAACCTGATCCCAATCTTTGAGGAGCTGAGCGGAGCAGAGGAC
  GTCTACACCAGCCTTGGGCAGCTGCGGGCCCCTTAG
  
  Clone variation with respect to NM_005730.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005730 unedited
  AGGCGGCCCGCGAATTCGCACGAGGGGAGCCCGGAGCTGCCGCTGGGGGATCGGGGCCGG
  GGGCACCCGGGGGAGCCGCTGCCCGGGCCGCCCGCCCTTTGTACAGGCCGCCTCCCTTCC
  CGGTCCGGGGAGGAAACGAGAGGGGGGATGTGAACAGCTGTGGAAGTCGGAGTCTCGGGA
  GCCGGAGCGGGCCCCCGCCCAGGCCCCCCAGCCCAGCCCAGCCCGCGCGCCCGCCCGTCC
  TCCCGCCCAGCCAGCCCGGGCCCGCGGGATTGTTAGATGGAACACGGCTCCATCATCACC
  CAGGCGCGGAGGGAAGACGCCCTGGTGCTCACCAAGCAAGGCCTGGTCTCCAAGTCCTCT
  CCTAAGAAGCCTCGTGGACGTAACATCTTCAAGGCCCTTTTCTGCTGTTTTCGCGCCCAG
  CATGTTGGCCAGTCAAGTTCCTCCACTGAGCTCGCTGCGTATAAGGAGGAAGCAAACACC
  ATTGCTAAGTCGGATCTGCTCCAGTGTCTCCAGTACCAGTTCTACCAGATCCCAGGGACC
  TGCCTGCTCCCAGAGGTGACAGAGGAAGATCAAGAAGGATCTGTGTGGTCATTGACCTCG
  ATGAAACCCTTGTGCATAGCTCCTTTAAGCCAATCAACAATGCTGACTTCATAGTGCCTA
  TAGAGATTGAGGGGACCACTCACCAGGNTGTATGTGCTCAANGAGCCTTTATGTGGATGA
  GCTCCTGAGACGCATGGNGGAACTCTTTGNATGTGTTCTGCTCACTGGCAGCCTGGCCAA
  GTATGCCGACCCTGTGACAGACTGCTGAACCGTGTGGGGGGGGTTCCGGCCCGCCTATTC
  GTGAGTTTTTTGGGTGTTCACCAAGGCTGGTCGTTAAGGACCTCAACGCTTGGGGGAGGA
  CCGAAAAGAACCTCTTCTGGACACTGGCTGCTTTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005730 unedited
  NNNNGGGGGGTGGGAGGTTTTTTAAACCCACTTTNTATAATTAATTGTAAGTAATACAAA
  TATTCCAAAAATATAAACAGACACTTAATGGCGTCCTGCATTTCAAGTTTTTGAATACAA
  CAAATTTATCAAACCATGAATCTGTAAGCAAGGTAGTCAGAATCCCATAGCCCAGTCACA
  GTGGGAAGCAGATCCCCTACCCTCCAAATGGCATCTTGAAGGGGGAAAGCGGCACGAAAT
  GGAACATGATAAGCAAAAAAGCTCACGAGGCCCAAAGAGGAGGGTCCGCTCCATGGGCAG
  GCCCTACAACGTTAAAAGAATGGGGCAGCTGGCCCGACCTCTGGCCTCCTCTTCCCTGGC
  TGAATGTAAATATTTACCAGCATTTAGAAAAAAGGAGAAAAAAGACAGAACTAAACCCGT
  TTAGGAAAAAGGGACCGAGGGACAGCAGTGGTTAAGTAATCCACTGAGGACCTGAAGGGG
  AAAATGGACTTACCTTTCTCATATACTTGGCCTGGCTAGGACACTGGGTGCCAGACAGCC
  TTCTGAGGGGATTTTCTTTCTAAATGAGGCCTCAGGAACAGGTAGGGGCAGCAGAATAGA
  ATAGCATCCATTTCCCAGAGAAAGACTGCCTTTACATTTCCCATGCTTTTAGCACAAAGC
  AGCGTCTGGGCCACTGTTACCAGAGGTGAGTTTATACATTTACAAAATGCTTAANATCTT
  TGGGAAGCAAGAGGAAGCTAAACAGAAGGTCCCATGTTAACTGAAGGCAAATTCACTCAA
  CCTCTCTAGTAAGGGACCCATGGGCCTACAGAGTGTTTCCTCTACAATGTGCAGAGTGGA
  AACCCTTACCTGAGCCTTTTCAGAAATGGTCCTGTGG
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_005730
• ORF Size: 852 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_005730.2, NP_005721.2
• RefSeq Size: 4833
• RefSeq ORF: 852
• Locus ID: 10106
• Domains: CPDc
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. [UniProtKB/Swiss-Prot Function]