CTDSP2 (NM_005730) Human Untagged Clone

CAT#: SC324051

CTDSP2 (untagged)-Human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (CTDSP2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CTDSP2
• Synonyms: OS4; PSR2; SCP2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005730.3 GGAGCTGCCGCTGGGGGATCGGGGCCGGGGGCACCCGGGGGAGCCGCTGCCCGGGCCGCC
  CGCCCTTTGTACAGGCCGCCTCCCTTCCCGGTCCGGGGAGGAAACGAGAGGGGGGATGTG
  AACAGCTGTGGAAGTCGGAGTCTCGGGAGCCGGAGCGGGCCCCCGCCCAGGCCCCCCAGC
  CCAGCCCAGCCCGCGCGCCCGCCCGTCCTCCCGCCCAGCCAGCCCGGGCCCGCGGGATTG
  TTAGATGGAACACGGCTCCATCATCACCCAGGCGCGGAGGGAAGACGCCCTGGTGCTCAC
  CAAGCAAGGCCTGGTCTCCAAGTCCTCTCCTAAGAAGCCTCGTGGACGTAACATCTTCAA
  GGCCCTTTTCTGCTGTTTTCGCGCCCAGCATGTTGGCCAGTCAAGTTCCTCCACTGAGCT
  CGCTGCGTATAAGGAGGAAGCAAACACCATTGCTAAGTCGGATCTGCTCCAGTGTCTCCA
  GTACCAGTTCTACCAGATCCCAGGGACCTGCCTGCTCCCAGAGGTGACAGAGGAAGATCA
  AGGAAGGATCTGTGTGGTCATTGACCTCGATGAAACCCTTGTGCATAGCTCCTTTAAGCC
  AATCAACAATGCTGACTTCATAGTGCCTATAGAGATTGAGGGGACCACTCACCAGGTGTA
  TGTGCTCAAGAGGCCTTATGTGGATGAGTTCCTGAGACGCATGGGGGAACTCTTTGAATG
  TGTTCTCTTCACTGCCAGCCTGGCCAAGTATGCCGACCCTGTGACAGACCTGCTGGACCG
  GTGTGGGGTGTTCCGGGCCCGCCTATTCCGTGAGTCTTGCGTGTTCCACCAGGGCTGCTA
  CGTCAAGGACCTCAGCCGCCTGGGGAGGGACCTGAGAAAGACCCTCATCCTGGACAACTC
  GCCTGCTTCTTACATATTCCACCCCGAGAATGCAGTGCCTGTGCAGTCCTGGTTTGATGA
  CATGGCAGACACTGAGTTGCTGAACCTGATCCCAATCTTTGAGGAGCTGAGCGGAGCAGA
  GGACGTCTACACCAGCCTTGGGCAGCTGCGGGCCCCTTAGCCTGCCCTGCTTCCAAGCGA
  CGGCCATCCCAGTAGGGGACTTTCCCACACTGTGCCTTTACGATCAGCGTGACAGAGTAG
  AAGCTGGAGTGCCTCACCACACGGCCCGGAAACAGCGGGAAGTAACTGGAAAGAGCTTTA
  GGACAGCTTAGATGCCGAGTGGGCGAATGCCAGACCAATGATACCCAGAGCTACCTGCCG
  CCAACTTGTTGAGATGTGTGTTTGACTGTGAGAGAGTGTGTGTTTGTGTGTGTGTTTTGC
  CATGAACTGTGGCCCCAGTGTATAGTGTTTCAGTGGGGGAGAAGCTGAAAGACCAAGACT
  CTTCCCAAGTTAGCTTGTCTCCTCTCCTGTCACCCTAAGAGCCACTGAGTTGTGTAGGGA
  TGAAGACTATTGAAGACTCCATTGCCAAACCATGGCCTTTCCTCAGTGTTGTAAGGCCTA
  TGCCAAGGATAAAGGAAGGGTATGCCTTTGGGTACTCCAGGCACACACCTTTCTGAAATC
  CTTCTCCAGCCAGCTGCTGCAGACAAAAGATCACATTTCTGGGAAGATGAGAACTTGTTT
  CCAGACCAGCATCCAGTGGCCATCAGGTCTTGTGGCCCAAAGGCTATGCTTGCCTCCGGC
  TGAGTGCCTGGGATAGGCCTTTTCTATGTCTCCCCAAGGCTGGGGTGCTGAGCCTGCCTT
  CCTCACCACCTAGCCATAGTCTCAAACCTGTGGGGAAGGAGGTTTTCTCCCTGCCCGGGA
  AGAGGACAGATAACTGATTTCCGTTCTTTTGACTGTGTTTTAAAATTCTCTTTCTAAACA
  CAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005730.3 unedited
  GGCGTTTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCC
  GGAATTCCCGGGATGGAGCTGCCGCTGGGGGATCGGGGCCGGGGGCACCCGGGGGAGCCG
  CTGCCCGGGCCGCCCGCCCTTTGTACAGGCCGCCTCCCTTCCCGGTCCGGGGAGGAAACG
  AGAGGGGGGATGTGAACAGCTGTGGAAGTCGGAGTCTCGGGAGCCGGAGCGGGCCCCCGC
  CCAGGCCCCCCAGCCCAGCCCAGCCCGCGCGCCCGCCCGTCCTCCCGCCCAGCCAGCCCG
  GGCCCGCGGGATTGTTAGATGGAACACGGCTCCATCATCACCCAGGCGCGGAGGGAAGAC
  GCCCTGGTGCTCACCAAGCAAGGCCTGGTCTCCAAGTCCTCTCCTAAGAAGCCTCGTGGA
  CGTAACATCTTCAAGGCCCTTTTCTGCTGTTTTCGCGCCCAGCATGTTGGCCAGTCAAGT
  TCCTCCACTGAGCTCGCTGCGTATAAGGAGGAAGCAAACACCATTGCTAAGTCGGATCTG
  CTCCAGTGTCTCCAGTACCAGTTCTACCAGATCCCAGGGACCTGCCTGCTCCCAGAGGTG
  ACAGAGGAAGATCAAGGAAGGATCTGTGTGGTCATTGACCTCGATGAAACCCTTGTGCAT
  AGGCTCCTTTAAGCCAATCAACAATGCTGACTTCATAGTGCCTATAGAGATTGAGGGGAC
  CACTCACCAGGTGTATGGTGCTCAAGAGGCCTTATGTGGATGAGTTCCTGAGACGCATGG
  GGGAACTCTTTTGAATGTGTTCTATTTCACTGACAACCGGTCCAGTATGGCCGACCCTGG
  GAACGAACTTGCTGGACCAGTGA
• Restriction Sites: ECoRI-NOT
• ACCN: NM_005730
• ORF Size: 816 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005730.3, NP_005721.3
• RefSeq Size: 5038
• RefSeq ORF: 816
• Locus ID: 10106
• Domains: CPDc
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. [UniProtKB/Swiss-Prot Function]