BCL3 (NM_005178) Human Untagged Clone

CAT#: SC128102

BCL3 (untagged)-Human B-cell CLL/lymphoma 3 (BCL3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BCL3
• Synonyms: BCL4; D19S37
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_005178 edited
  ATGCCCCAATGCCCCGCGGGGGCCATGGACGAGGGGCCCGTGGACCTGCGCACCCGGCCC
  AAGGCCGCCGGACTCCCGGGCGCCGCGCTGCCGCTCCGCAAGCGCCCGCTGCGCGCGCCC
  TCCCCGGAGCCCGCCGCTCCCCGCGGCGCTGCGGGCCTTGTCGTCCCCCTGGACCCTCTG
  CGCGGCGGCTGCGACCTGCCGGCGGTCCCCGGGCCCCCCCACGGCCTGGCCCGGCCGGAG
  GCGCTTTACTACCCCGGAGCCTTACTGCCTTTGTACCCCACTCGGGCCATGGGCTCCCCG
  TTTCCTCTGGTGAACCTGCCTACACCCCTATACCCCATGATGTGCCCCATGGAACACCCC
  CTTTCTGCTGACATCGCCATGGCCACCCGTGCAGATGAGGACGGAGACACGCCTCTCCAT
  ATTGCTGTGGTGCAGGGTAACCTGCCAGCTGTGCACCGGCTGGTCAACCTCTTCCAGCAG
  GGGGGCCGGGAGCTCGACATCTACAACAACCTACGGCAGACACCGCTCCACCTGGCTGTG
  ATCACCACATTACCGTCTGTGGTCCGGCTCCTGGTGACAGCTGGTGCCAGCCCCATGGCG
  CTGGACCGCCATGGCCAGACGGCCGCTCACCTGGCGTGCGAGCACCGCAGCCCGACCTGC
  CTGCGAGCCCTGCTGGACAGCGCAGCTCCGGGCACGTTGGACCTGGAGGCCCGCAATTAT
  GACGGGCTCACCGCCCTGCACGTGGCAGTGAACACCGAGTGCCAAGAAACCGTGCAGCTC
  TTGCTAGAGCGCGGTGCCGACATCGACGCAGTGGACATTAAGAGCGGCCGCTCCCCGCTC
  ATCCACGCCGTGGAAAACAACAGCCTTAGCATGGTGCAGCTGCTGCTGCAGCACGGCGCC
  AACGTGAACGCGCAAATGTACTCCGGCAGCTCCGCCCTGCACTCAGCGTCCGGCCGCGGG
  CTCCTCCCGCTGGTGCGCACGCTGGTCCGCAGCGGCGCTGACAGCAGCCTCAAGAACTGC
  CACAACGACACGCCGCTCATGGTGGCGCGCAGCCGCAGGGTCATCGACATCCTGAGGGGG
  AAGGCCACCCGGCCTGCTTCCACCTCCCAGCCAGACCCCTCCCCTGACCGGAGCGCCAAC
  ACCTCCCCCGAGAGCAGCAGCCGCCTCAGCTCCAATGGTCTTCTCTCCGCATCACCATCC
  TCCTCACCCTCCCAGTCTCCCCCCAGGGACCCCCCTGGATTCCCCATGGCTCCTCCCAAT
  TTCTTCCTTCCTTCCCCATCTCCACCCGCCTTCCTGCCCTTTGCTGGGGTCCTCCGAGGC
  CCTGGCCGGCCGGTGCCCCCCTCCCCAGCTCCAGGAGGCAGCTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005178 unedited
  TTTGTAATACGACTCACTATAGGGCGGCACGCGAATTCGCACCAGGCCGGCACCGCCCCG
  GCCGACAAAAGTCCCTTCATTTCATCCGGCTGCAGGGGAAGTCCCGGCGCCCGGCGAAAC
  CACCCTCCCGTGCAGCCGAGCCCATCCGCTCTCCGGCCGCCGTCCCCGGCGGCCCCATGC
  CCCAATGCCCCGCGGGGGCCATGGACGATGGGCCCGTGGACCTGCGCACCCGGCCCAAGG
  CCGCCGGACTCCCGGGCGCCGCGCTGCCGCTCCGCAAGCGCCCGCTGCGCGCGCCCTCCC
  CGGAGCCCGCCGCTCCCCGCGGCGCTGCGGGCCTTGTCGTCCCCCTGGACCCTCTGCGCG
  GCGGCTGCGACCTGCCGGCGGTCCCCGGGCCCCCCCACGGCCTGGCCCGGCCGGAGGCGC
  TTTACTACCCCGGAGCCTTACTGCCTTTGTACCCCACTCGGGCCATGGGCTCCCCGTTTC
  CTCTGGTGAACCTGCCTACACCCCTATACCCCATGATGTGCCCCATGGAACACCCCCTTT
  CTGCTGACATCGCCATGGCCACCCGTGCAGATGATGACGGAGACACGCCTCTCCATATTG
  CTGTGGTGCATGGTAACCTGCCAGCTGTGCACCGGCTGGTCAACCTCCTTCAGCATGGAG
  GGCCCGGGAGCTCGACATCTACAACAACCTACAGCAGACACCGCTNCACCTGGCTGTGAT
  CACCACATTACCGTCTGTAGTCCAGCTCCTGGTGACAGCTGGTGCCAGCCCCATGGCGCT
  AGACCGNCATGCCCAGATCGGCGCTCACCTGGCGTGCGATCACCGCATCCCGACCTGCCT
  GCGAGCCCTGCTGGAAGCGCATCTCAGGCACGTTGGACCTGGAGCCNGCATTATGAGGNC
  TCACGNCCTGCACGTGCATGACACCGATGCCATAATCGGCAGTCTGCTAATCCGTGCGAC
  TCNACCATGGCATTAGACGGNCGTCCGTCATCAGCGGGAACACANCTANATGGGACTGTG
  TGANAGGGCCACG
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_005178 unedited
  TTTTTTTTTTTTTTTATGGTACAAAATAGTTTATTACAAAANAAATCCAACCAAAATGCT
  TAATAATTTACATCGTGATCCGTGCCCGTTACGGCCCACCTCTCCCCTCCTCAGTTATCT
  GGTAGAGAGTGGAGGGGAGTGGCTGTTCCCTGGGTCCACCAGCTCTGGGAGGGGACATGG
  AAATGGAAGATGTGGGTGGCATTCCGGACAGGGACTGGTGCCTGAGAATGCTGGGGTCAG
  AGTCCTGGGAGGGAGCGAGATGGGGGAACATCTGTGCTCACAAGAGGGGGTGTATGGGTA
  GGTGCATGTGCTTCTGTGCAAATCCTGGTCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005178
• ORF Size: 1341 bp
• Insert Size: 2000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005178.2, NP_005169.1
• RefSeq Size: 1813
• RefSeq ORF: 1341
• Locus ID: 602
• Domains: ANK
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008]