BCL3 (NM_005178) Human Untagged Clone

CAT#: SC317743

BCL3 (untagged)-Human B-cell CLL/lymphoma 3 (BCL3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BCL3
• Synonyms: BCL4; D19S37
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005178, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCCCGATGCCCCGCGGGGGCCATGGACGAGGGGCCCGTGGACCTGCGCACCCGGCCCAAGGCCGCCG
  GACTCCCGGGCGCCGCGCTGCCGCTCCGCAAGCGCCCGCTGCGCGCGCCCTCCCCGGAGCCCGCCGCTCC
  CCGCGGCGCTGCGGGCCTTGTCGTCCCCCTGGACCCTCTGCGCGGCGGCTGCGACCTGCCGGCGGTCCCC
  GGGCCCCCCCACGGCCTGGCCCGGCCGGAGGCGCTTTACTACCCCGGAGCCTTACTGCCTTTGTACCCCA
  CTCGGGCCATGGGCTCCCCGTTTCCTCTGGTGAACCTGCCTACACCCCTATACCCCATGATGTGCCCCAT
  GGAACACCCCCTTTCTGCTGACATCGCCATGGCCACCCGTGCAGATGAGGACGGAGACACGCCTCTCCAT
  ATTGCTGTGGTGCAGGGTAACCTGCCAGCTGTGCACCGGCTGGTCAACCTCTTCCAGCAGGGGGGCCGGG
  AGCTCGACATCTACAACAACCTACGGCAGACACCGCTCCACCTGGCTGTGATCACCACATTACCGTCTGT
  GGTCCGGCTCCTGGTGACAGCTGGTGCCAGCCCCATGGCGCTGGACCGCCATGGCCAGACGGCCGCTCAC
  CTGGCGTGCGAGCACCGCAGCCCGACCTGCCTGCGAGCCCTGCTGGACAGCGCAGCTCCGGGCACGTTGG
  ACCTGGAGGCCCGCAATTATGACGGGCTCACCGCCCTGCACGTGGCAGTGAACACCGAGTGCCAAGAAAC
  CGTGCAGCTCTTGCTAGAGCGCGGTGCCGACATCGACGCAGTGGACATTAAGAGCGGCCGCTCCCCGCTC
  ATCCACGCCGTGGAAAACAACAGCCTTAGCATGGTGCAGCTGCTGCTGCAGCACGGCGCCAACGTGAACG
  CGCAAATGTACTCCGGCAGCTCCGCCCTGCACTCAGCGTCCGGCCGCGGGCTCCTCCCGCTGGTGCGCAC
  GCTGGTCCGCAGCGGCGCTGACAGCAGCCTCAAGAACTGCCACAACGACACGCCGCTCATGGTGGCGCGC
  AGCCGCAGGGTCATCGACATCCTGAGGGGGAAGGCCACCCGGCCTGCTTCCACCTCCCAGCCAGACCCCT
  CCCCTGACCGGAGCGCCAACACCTCCCCCGAGAGCAGCAGCCGCCTCAGCTCCAATGGTCTTCTCTCCGC
  ATCACCATCCTCCTCACCCTCCCAGTCTCCCCCCAGGGACCCCCCTGGATTCCCCATGGCTCCTCCCAAT
  TTCTTCCTTCCTTCCCCATCTCCACCCGCCTTCCTGCCCTTTGCTGGGGTCCTCCGAGGCCCTGGCCGGC
  CGGTGCCCCCCTCCCCAGCTCCAGGAGGCAGCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_005178
• ORF Size: 1365 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005178.4, NP_005169.2
• RefSeq Size: 1864
• RefSeq ORF: 1365
• Locus ID: 602
• Domains: ANK
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008]