KDM4C (NM_015061) Human Untagged Clone

CAT#: SC128199

KDM4C (untagged)-Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KDM4C
• Synonyms: GASC1; JHDM3C; JMJD2C; TDRD14C
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015061 edited
  CCTCGACGGGAGGGTGAGGCGCGGCGCAGTGATCGGGCGGCCGGGGTCCTGTGCGCGTGC
  GCAGCGAACAGCTGTCACCTAGTGCGGAACAAGTCTCCCAAATTTCCCAAATCTCCCTGG
  GCCGGAGGCCACTGTCTTCTCTTCCTCCTCCACCGAGTCGTGCTCTCGCCCCAACCCGCG
  CGCCAGACACTGCCCTAACCATCATGGAGGTGGCCGAGGTGGAAAGTCCTCTGAACCCCA
  GCTGTAAGATAATGACCTTCAGACCCTCCATGGAGGAGTTCCGGGAGTTCAACAAATACC
  TTGCATACATGGAGTCTAAAGGAGCCCATCGTGCGGGTCTTGCAAAGGTGATTCCTCCTA
  AGGAGTGGAAGCCAAGACAGTGCTATGATGACATTGATAATTTGCTCATTCCAGCACCAA
  TTCAGCAGATGGTCACAGGGCAGTCAGGACTGTTCACTCAGTACAACATCCAGAAAAAAG
  CGATGACTGTGAAGGAGTTCAGGCAGCTGGCCAACAGTGGCAAATATTGTACTCCAAGAT
  ACTTGGATTACGAAGATTTGGAGCGCAAGTACTGGAAGAACTTAACTTTTGTGGCACCTA
  TCTATGGTGCAGATATTAATGGGAGCATATATGATGAGGGTGTGGATGAATGGAACATAG
  CTCGCCTCAATACAGTCTTGGATGTGGTTGAAGAAGAGTGTGGCATTTCTATTGAGGGTG
  TAAATACCCCATATCTCTATTTTGGCATGTGGAAGACCACGTTTGCATGGCACACCGAAG
  ACATGGACCTCTATAGCATTAATTATCTCCACTTTGGAGAGCCCAAGTCTTGGTATGCTA
  TACCTCCGGAGCATGGAAAACGACTTGAAAGACTAGCTCAAGGTTTTTTCCCAAGCAGCT
  CCCAAGGGTGTGATGCATTTCTTCGCCACAAGATGACATTGATTTCTCCATCAGTATTGA
  AGAAATATGGTATTCCCTTTGACAAGATAACCCAGGAGGCTGGAGAATTCATGATCACTT
  TCCCATATGGCTACCATGCTGGTTTTAATCATGGTTTCAACTGTGCAGAATCTACAAATT
  TTGCTACTGTCAGATGGATTGACTATGGAAAAGTTGCCAAATTGTGCACTTGCAGGAAAG
  ACATGGTGAAGATTTCAATGGATATCTTTGTGAGGAAATTTCAGCCAGACAGATATCAGC
  TTTGGAAACAAGGAAAGGATATATACACCATTGATCACACGAAGCCTACTCCAGCATCCA
  CCCCTGAAGTAAAAGCATGGCTGCAGAGGAGGAGGAAAGTAAGAAAAGCATCCCGAAGCT
  TCCAGTGTGCTAGGTCTACCTCTAAAAGGCCTAAGGCTGATGAGGAAGAGGAAGTGTCAG
  ATGAAGTCGATGGGGCAGAGGTCCCTAACCCCGACTCAGTCACAGATGACCTCAAGGTCA
  GTGAAAAGTCAGAAGCAGCAGTGAAGCTGAGGAACACAGAAGCATCTTCAGAAGAAGAGT
  CATCTGCTAGCAGGATGCAGGTGGAGCAGAATTTATCAGATCATATCAAACTCTCAGGAA
  ACAGCTGCTTAAGTACATCTGTAACAGAAGACATAAAAACTGAGGATGACAAAGCTTATG
  CATATAGAAGTGTACCTTCTATATCCAGTGAGGCTGATGATTCCATTCCATTGTCTAGTG
  GCTATGAGAAGCCCGAGAAATCAGACCCATCCGAGCTTTCATGGCCAAAGTCACCTGAGT
  CATGCTCATCAGTGGCAGAGAGTAATGGTGTGTTAACAGAGGGAGAAGAGAGTGATGTGG
  AGAGCCATGGGAATGGCCTTGAACCTGGGGAAATCCCAGCGGTCCCCAGTGGAGAGAGAA
  ATAGCTTCAAAGTCCCCAGTATAGCAGAGGGAGAGAACAAAACCTCTAAGAGTTGGCGCC
  ATCCACTTAGCAGGCCTCCAGCAAGATCTCCGATGACTCTTGTGAAGCAGCAGGCGCCAA
  GTGATGAAGAATTGCCTGAGGTTCTGTCCATTGAGGAGGAAGTGGAAGAAACAGAGTCTT
  GGGCGAAACCTCTCATCCACCTTTGGCAGACGAAGTCCCCTAACTTCGCAGCTGAGCAAG
  AGTATAATGCAACAGTGGCCAGGATGAAGCCACACTGTGCCATCTGCACTCTGCTCATGC
  CGTACCACAAGCCAGATAGCAGCAATGAAGAAAATGATGCTAGATGGGAGACAAAATTAG
  ATGAAGTCGTTACATCGGAGGGAAAGACTAAGCCCCTCATACCAGAGATGTGTTTTATTT
  ATAGTGAAGAAAATATAGAATATTCTCCACCCAATGCCTTCCTTGAAGAGGATGGAACAA
  GTCTCCTTATTTCCTGTGCAAAGTGCTGCGTACGGGTTCATGCAAGTTGTTATGGTATTC
  CTTCTCATGAGATCTGTGATGGATGGCTGTGTGCCCGGTGCAAAAGAAATGCGTGGACAG
  CAGAATGCTGTCTCTGCAATTTGAGAGGAGGTGCTCTTAAGCAAACGAAGAACAATAAGT
  GGGCCCATGTCATGTGCGCCGTTGCGGTCCCAGAAGTTCGATTCACTAATGTCCCAGAAA
  GGACACAAATAGATGTAGGCAGAATACCTTTACAGAGGTTAAAATTGAAATGCATCTTCT
  GCAGACACCGGGTTAAGAGGGTCTCTGGAGCCTGCATCCAGTGTTCCTACGGTCGCTGCC
  CGGCCTCCTTCCATGTCACTTGTGCCCATGCTGCTGGGGTACTGATGGAGCCTGATGATT
  GGCCTTATGTGGTGAACATTACATGCTTTCGACATAAGGTCAACCCCAACGTGAAGTCCA
  AGGCTTGCGAGAAGGTCATTTCCGTGGGTCAAACGGTCATCACGAAGCATCGGAACACCC
  GGTATTACAGTTGCAGAGTGATGGCTGTGACATCGCAGACCTTCTATGAGGTCATGTTTG
  ATGATGGCTCCTTTAGCAGAGACACATTTCCTGAGGATATCGTGAGCCGAGACTGTCTGA
  AGCTGGGCCCACCTGCTGAGGGAGAAGTCGTCCAAGTCAAGTGGCCCGATGGCAAACTCT
  ATGGAGCAAAATATTTTGGATCAAATATTGCCCACATGTACCAGGTTGAGTTTGAAGATG
  GATCCCAGATAGCAATGAAGAGAGAGGACATCTACACTTTAGATGAAGAGTTACCCAAGA
  GAGTGAAAGCTCGATTTTCCACAGCCTCTGACATGCGATTTGAAGACACGTTTTATGGAG
  CAGACATTATCCAAGGGGAGAGAAAGAGACAAAGAGTGCTGAGCTCCAGGTTTAAGAATG
  AATATGTGGCCGACCCTATATACCGCACTTTTTTGAAGAGCTCTTTCCAGAAGAAGTGCC
  AGAAGAGACAGTAGTCTGCATACATCGCTGCAGGCCACAGAGCAGCTTGGGTTGGAAAAG
  AGAAGATGAAGGGACATCCTTGGGGCTGTGCCGTGAGATTTGCTGGCATAGGTGACAGGG
  TGTGTCTCTGACAGTGGTAAATCGGGTTTCCAGAGTTTGGTCACCAAAAATACAAAATAC
  ACMCAATGAATTGGACGCAGCAATCTGAAATCATCTCTAGTCTTGCTTTCACTTGTGAGC
  AGTTGTCTTCTATGATCCCAAAGAAGTTTTCTAAGTGAAAGGAAATACTAGTGAATCACC
  CACAAGGAAAAGCCACTGCCACAGAGGAGGCGGGTCCCCTTGTGCGGCTTAGGGCCCTGT
  CAGGAAACACACGGGGACCTCTCTCTCTAGCTCCAGCAGGTGGCACCTCGGTACCCAGCG
  GGTAGGGCGATAATTTATATATTTTCCACAGTCAGGGAAGGACTCTCACTTATTTGTTTC
  AAATTGCAGTTTTTATAAAACATTTTTAAAACACAAATGGCATGTATGCTAATGAGATTT
  ACCCGTGTGCTATCTGTATTTCCCTTGTACAGAACTTTTACATTTTTGAATATTCCTATT
  ACTTTTGATTGTGTCTGATGGGAACTGAGTTGTTGGCCTTTGTGAAATGAAATTTTTGGC
  TCTTGAGAAAGAATTCTTATGAATTGTTATGCGAATTTTATATATTTAAAGAGGGAGATC
  TGGGGCTGTTATTTTTAAACACTTTTTTTCATAATACATATTCCGAGTAGATATTTATAA
  AATATATGTTTCTTTCATTATGTGTTTGTAAAATTAGAGTTTAAATAAATATGCTTTGAT
  GCATAGTTTTGAACTAATGTAACATGATTTTTCTTTTTTAAAACAGCCTGAAAATGTACT
  AGTGTTTAAAAATAAAGATTTCCATTTTCTCCAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015061
• ORF Size: 3171 bp
• Insert Size: 4300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015061.2, NP_055876.2
• RefSeq Size: 4674
• RefSeq ORF: 3171
• Locus ID: 23081
• Domains: PHD, TUDOR, JmjC, JmjN
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).