MTUS1 (NM_001001924) Human Untagged Clone

CAT#: SC300343

MTUS1 (untagged)-Human microtubule associated tumor suppressor 1 (MTUS1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MTUS1
• Synonyms: ATBP; ATIP; ATIP3; ICIS; MP44; MTSG1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001001924, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACTGATGATAATTCAGATGATAAAATAGAAGATGAATTGCAAACCTTCTTTACCAGTGATAAAGATG
  GAAATACACATGCATACAACCCGAAATCACCACCTACACAAAACTCTTCAGCCAGCAGTGTGAACTGGAA
  TTCTGCCAACCCAGATGACATGGTGGTTGATTATGAAACTGACCCTGCTGTAGTTACTGGTGAAAATATT
  TCTTTAAGCCTTCAGGGTGTTGAAGTATTTGGTCATGAAAAGTCTTCTAGTGATTTCATTAGTAAGCAGG
  TGTTAGATATGCATAAAGATTCTATTTGTCAGTGTCCTGCACTTGTAGGTACTGAGAAGCCCAAATATCT
  GCAACACAGTTGTCATTCCCTAGAAGCAGTTGAGGGCCAGAGTGTTGAGCCATCTTTGCCTTTTGTGTGG
  AAGCCTAATGACAATTTGAACTGTGCAGGCTACTGTGATGCCTTGGAGCTAAACCAAACATTTGACATGA
  CAGTGGATAAAGTTAACTGCACCTTTATATCACATCATGCCATCGGAAAGAGTCAGTCCTTCCATACTGC
  TGGAAGCCTGCCACCAACTGGTAGGAGAAGTGGAAGTACATCTTCTTTATCCTATTCCACTTGGACATCT
  TCCCATTCTGATAAGACGCATGCAAGAGAAACTACTTATGATAGAGAAAGCTTTGAAAACCCTCAAGTCA
  CACCATCAGAAGCCCAAGACATGACTTACACAGCATTTTCTGATGTGGTGATGCAAAGTGAGGTTTTTGT
  TTCAGATATTGGAAATCAGTGTGCATGTTCTTCAGGAAAGGTCACCAGTGAGTACACAGATGGATCACAA
  CAAAGACTAGTTGGAGAAAAGGAGACACAAGCACTAACACCAGTTTCTGATGGCATGGAAGTCCCCAATG
  ATTCTGCATTACAAGAGTTCTTTTGTTTATCCCATGATGAATCCAATAGCGAACCACATTCACAGAGCTC
  ATACAGGCACAAGGAAATGGGCCAAAATCTGAGAGAGACAGTGTCCTATTGTCTTATTGATGATGAATGC
  CCTTTAATGGTGCCAGCTTTTGATAAGAGCGAAGCTCAAGTGCTGAACCCAGAGCATAAAGTCACTGAGA
  CTGAAGACACACAAATGGTCTCCAAAGGAAAGGATTTGGGAACCCAAAATCATACCTCAGAATTGATTCT
  AAGTAGCCCGCCAGGACAAAAGGTGGGCTCGTCATTTGGACTGACTTGGGATGCAAATGATATGGTCATT
  AGCACAGACAAAACGATGTGCATGTCAACACCAGTCCTAGAACCCACAAAAGTAACCTTTTCTGTTTCAC
  CGATTGAAGCGACGGAGAAATGTAAGAAAGTGGAGAAGGGTAATCGAGGGCTTAAAAACATACCAGACTC
  GAAGGAGGCACCTGTGAACCTGTGTAAACCCAGTTTAGGAAAATCAACAATCAAAACGAATACCCCAATA
  GGCTGCAAAGTTAGAAAAACTGAAATTATAAGTTACCCAAGACCAAACTTCAAGAATGTCAAAGCAAAAG
  TTATGTCTAGAGCAGTGTTGCAGCCCAAAGATGCTGCTTTATCAAAGGTCACGCCCAGACCTCAGCAGAC
  CAGTGCCTCATCACCCTCATCAGTGAATTCAAGACAACAAACAGTCTTGAGCAGAACACCGAGATCTGAC
  TTGAATGCAGACAAAAAAGCAGAAATTCTAATTAACAAGACACATAAGCAGCAGTTTAATAAACTCATTA
  CTAGCCAGGCTGTGCATGTTACAACTCATTCTAAAAATGCTTCACACAGGGTTCCAAGAACAACATCTGC
  CGTGAAATCGAATCAGGAAGATGTTGACAAAGCCAGTTCTTCTAACTCAGCATGCGAGACCGGGTCCGTT
  TCTGCGTTGTTTCAGAAGATCAAAGGCATACTCCCTGTTAAAATGGAAAGTGCAGAATGTTTGGAAATGA
  CCTATGTTCCCAACATTGATAGGATTAGCCCTGAAAAGAAGGGTGAAAAAGAAAATGGGACATCTATGGA
  AAAACAAGAGCTGAAACAAGAGATTATGAATGAGACTTTTGAATATGGTTCTCTGTTTTTGGGCTCTGCT
  TCAAAAACAACGACCACCTCAGGTAGGAATATATCCAAGCCTGACTCCTGCGGTTTGAGGCAAATAGCTG
  CTCCAAAAGCCAAAGTGGGGCCCCCTGTTTCCTGTTTGAGGCGGAACAGTGACAATAGAAATCCCAGTGC
  TGATCGAGCCGTATCTCCTCAGAGGATCAGGCGTGTGTCCAGTTCTGGAAAGCCTACATCCTTGAAAACT
  GCACAGTCGTCATGGGTGAATTTGCCTAGACCACTTCCTAAATCCAAAGCATCTTTGAAAAGTCCTGCGC
  TGCGGAGGACAGGAAGCACCCCCTCAATAGCCAGCACCCACAGTGAGCTGAGCACTTACAGCAACAATTC
  TGGTAATGCCGCTGTCATCAAATATGAGGAGAAACCTCCAAAACCAGCATTTCAGAATGGTTCCTCAGGA
  TCCTTTTATTTGAAGCCTTTGGTATCCAGGGCTCATGTTCACTTGATGAAAACTCCTCCAAAAGGTCCTT
  CGAGAAAAAATTTATTTACAGCTCTTAATGCAGTTGAAAAGAGCAGGCAAAAGAATCCTCGAAGCTTATG
  TATCCAGCCACAGACAGCTCCCGATGCGCTGCCCCCTGAGAAAACACTTGAATTGACGCAATATAAAACA
  AAATGTGAAAACCAAAGTGGATTTATCCTGCAGCTCAAGCAGCTTCTTGCCTGTGGTAATACCAAGTTTG
  AGGCATTGACAGTTGTGATTCAGCACCTGCTGTCTGAGCGGGAGGAAGCACTGAAACAACACAAAACCCT
  ATCTCAAGAACTTGTTAACCTCCGGGGAGAGCTAGTCACTGCTTCAACCACCTGTGAGAAATTAGAAAAA
  GCCAGGAATGAGTTACAAACAGTGTATGAAGCATTCGTCCAGCAGCACCAGGCTGAAAAAACAGAACGAG
  AGAATCGGCTTAAAGAGTTTTACACCAGGGAGTATGAAAAGCTTCGGGACACTTACATTGAAGAAGCAGA
  GAAGTACAAAATGCAATTGCAAGAGCAGTTTGACAACTTAAATGCTGCGCATGAAACCTCTAAGTTGGAA
  ATTGAAGCTAGCCACTCAGAGAAACTTGAATTGCTAAAGAAGGCCTATGAAGCCTCCCTTTCAGAAATTA
  AGAAAGGCCATGAAATAGAAAAGAAATCGCTTGAAGATTTACTTTCTGAGAAGCAGGAATCGCTAGAGAA
  GCAAATCAATGATCTGAAGAGTGAAAATGATGCTTTAAATGAAAAATTGAAATCAGAAGAACAAAAAAGA
  AGAGCAAGAGAAAAAGCAAATTTGAAAAATCCTCAGATCATGTATCTAGAACAGGAGTTAGAAAGCCTGA
  AAGCTGTGTTAGAGATCAAGAATGAGAAACTGCATCAACAGGACATCAAGTTAATGAAAATGGAGAAACT
  GGTGGACAACAACACAGCATTGGTTGACAAATTGAAGCGTTTCCAGCAGGAGAATGAAGAATTGAAAGCT
  CGGATGGACAAGCACATGGCAATCTCAAGGCAGCTTTCCACGGAGCAGGCTGTTCTGCAAGAGTCGCTGG
  AGAAGGAGTCGAAAGTCAACAAGCGACTCTCTATGGAAAACGAGGAGCTTCTGTGGAAACTGCACAATGG
  GGACCTGTGTAGCCCCAAGAGATCCCCCACATCCTCCGCCATCCCTTTGCAGTCACCAAGGAATTCGGGC
  TCCTTCCCTAGCCCCAGCATTTCACCCAGATGA
  
  
• Restriction Sites: Please inquire
• ACCN: NM_001001924
• Insert Size: 3800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001001924.1, NP_001001924.1
• RefSeq Size: 6391 bp
• RefSeq ORF: 3813 bp
• Locus ID: 57509
• Cytogenetics: 8p22
• Protein Families: Druggable Genome, Transcription Factors, Transmembrane
• Gene Summary: This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1), also known as ATIP3, encodes the longest isoform (1).