SP140 (NM_001005176) Human Untagged Clone

CAT#: SC300816

SP140 (untagged)-Human SP140 nuclear body protein (SP140), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SP140
• Synonyms: LYSP100; LYSP100-A; LYSP100-B
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001005176 edited
  CTTTGACTGAGCACCGAGGGGCAGTTGGCAGCTTCACCTCAGAGCTGCAGGAAGGAACGG
  GGCAGTGAAAATCGAATCGGGTGTGATCCTAGGCCAAGCTCATGGCCCAGCAGGGCCAGC
  AGGGGCAGATGGCAAGTGGAGACAGCAATCTCAACTTCAGGATGGTCGCAGAGATCCAGA
  ACGTAGAGGGTCAGAACCTGCAGGAGCAGGTTTGCCCTGAGCCCATTTTCAGGTTCTTCA
  GAGAAAACAAGGTGGAGATTGCAAGTGCAATAACAAGGCCATTTCCTTTCCTTATGGGCC
  TCCGAGACCGCTCCTTCATCTCCGAGCAGATGTATGAACATTTTCAAGAAGCTTTTAGAA
  ACCTGGTCCCAGTGACAAGAGTGATGTATTGTGTACTCAGTGAACTGGAGAAGACATTTG
  GCTGGTCACATCTGGAAGCATTGTTCAGCAGGATTAACCTGATGGCCTATCCTGATTTAA
  ACGAGATTTACAGAAGCTTCCAGAATGAAAATTTATCATCCAGTGCAGTCCTGTGTCAAC
  TTGTTTCTCCAAACAAAGACTGGAGAAGTCACGAAGAGAGCCTAGCACATACTGGTACAC
  TGAGGAGGAGCTGCATGTGAAAGCTATGAAGACAGAAAAGGGGGTTGGTGGGGGCCTTTC
  CGAACCATGTGGTTGAATTGCAGACTGTGGGAGGCAGGGTGTGAGAGCTGACTCTGGAGA
  AAGAAGTTGAAGTGGATTCTGGAAGGCTTGACACCCTGTGCTAAGGAATCTGGAGTTTAA
  TTTTTGGAAAATAAAGAAGGAATAAAGGGCATTTAAACGGGAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001005176
• ORF Size: 519 bp
• Insert Size: 800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001005176.1.

Reference Data

• RefSeq: NM_001005176.1, NP_001005176.1
• RefSeq Size: 853
• RefSeq ORF: 519
• Locus ID: 11262
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
  Transcript Variant: This variant (2) lacks multiple 3' exons, and has an alternate 3' sequence, as compared to variant 1. The encoded isoform 2 is much shorter and has a distinct C-terminus, as compared to isoform 1.