ASAH3L (ACER2) (NM_001010887) Human Untagged Clone

CAT#: SC301506

ACER2 (untagged)-Human alkaline ceramidase 2 (ACER2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACER2
• Synonyms: ALKCDase2; ASAH3L
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001010887, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGCGCCCCGCACTGGTGGGACCAGCTGCAGGCTGGTAGCTCGGAGGTGGACTGGTGCGAGGACAACT
  ACACCATCGTGCCTGCTATCGCCGAGTTCTACAACACGATCAGCAATGTCTTATTTTTCATTTTACCGCC
  CATCTGCATGTGCTTGTTTCGTCAGTATGCAACATGCTTCAACAGTGGCATCTACTTAATCTGGACTCTT
  TTGGTTGTAGTGGGAATTGGATCCGTCTACTTCCATGCAACCCTTAGTTTCTTGGGTCAGATGCTTGATG
  AACTTGCAGTCCTTTGGGTTCTGATGTGTGCTTTGGCCATGTGGTTCCCCAGAAGGTATCTACCAAAGAT
  CTTTCGGAATGACCGGGGTAGGTTCAAGGTGGTGGTCAGTGTCCTGTCTGCGGTTACGACGTGCCTGGCA
  TTTGTCAAGCCTGCCATCAACAACATCTCTCTGATGACCCTGGGAGTTCCTTGCACTGCACTGCTCATCG
  CAGAGCTAAAGAGGTGTGACAACATGCGTGTGTTTAAGCTGGGCCTCTTCTCGGGCCTCTGGTGGACCCT
  GGCCCTGTTCTGCTGGATCAGTGACCGAGCTTTCTGCGAGCTGCTGTCATCCTTCAACTTCCCCTACCTG
  CACTGCATGTGGCACATCCTCATCTGCCTTGCTGCCTACCTGGGCTGTGTATGCTTTGCCTACTTTGATG
  CTGCCTCAGAGATTCCTGAGCAAGGCCCTGTCATCAAGTTCTGGCCCAATGAGAAATGGGCCTTCATTGG
  TGTCCCCTATGTGTCCCTCCTGTGTGCCAACAAGAAATCATCAGTCAAGATCACGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001010887
• ORF Size: 828 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001010887.2, NP_001010887.2
• RefSeq Size: 2852
• RefSeq ORF: 828
• Locus ID: 340485
• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism
• Gene Summary: The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [PubMed 16940153]). [supplied by OMIM, Jul 2010]