TrkC (NTRK3) (NM_001012338) Human Untagged Clone

CAT#: SC301636

NTRK3 (untagged)-Human neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), transcript variant 1


  "NM_001012338" in other vectors (7)

Reconstitution Protocol

USD 1,710.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol NTRK3
Synonyms gp145(trkC); GP145-TrkC; TRKC
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_001012338 edited
ATGGATGTCTCTCTTTGCCCAGCCAAGTGTAGTTTCTGGCGGATTTTCTTGCTGGGAAGC
GTCTGGCTGGACTATGTGGGCTCCGTGCTGGCTTGCCCTGCAAATTGTGTCTGCAGCAAG
ACTGAGATCAATTGCCGGCGGCCGGACGATGGGAACCTCTTCCCCCTCCTGGAAGGGCAG
GATTCAGGGAACAGCAATGGGAACGCCAGTATCAACATCACGGACATCTCAAGGAATATC
ACTTCCATACACATAGAGAACTGGCGCAGTCTTCACACGCTCAACGCCGTGGACATGGAG
CTCTACACCGGACTTCAAAAGCTGACCATCAAGAACTCAGGACTTCGGAGCATTCAGCCC
AGAGCCTTTGCCAAGAACCCCCATTTGCGTTATATAAACCTGTCAAGTAACCGGCTCACC
ACACTCTCGTGGCAGCTCTTCCAGACGCTGAGTCTTCGGGAATTGCAGTTGGAGCAGAAC
TTTTTCAACTGCAGCTGTGACATCCGCTGGATGCAGCTCTGGCAGGAGCAGGGGGAGGCC
AAGCTCAACAGCCAGAACCTCTACTGCATCAACGCTGATGGCTCCCAGCTTCCTCTCTTC
CGCATGAACATCAGTCAGTGTGACCTTCCTGAGATCAGCGTGAGCCACGTCAACCTGACC
GTACGAGAGGGTGACAATGCTGTTATCACTTGCAATGGCTCTGGATCACCCCTTCCTGAT
GTGGACTGGATAGTCACTGGGCTGCAGTCCATCAACACTCACCAGACCAATCTGAACTGG
ACCAATGTTCATGCCATCAACTTGACGCTGGTGAATGTGACGAGTGAGGACAATGGCTTC
ACCCTGACGTGCATTGCAGAGAACGTGGTGGGCATGAGCAATGCCAGTGTTGCCCTCACT
GTCTACTATCCCCCACGTGTGGTGAGCCTGGAGGAGCCTGAGCTGCGCCTGGAGCACTGC
ATCGAGTTTGTGGTGCGTGGCAACCCCCCACCAACGCTGCACTGGCTGCACAATGGGCAG
CCTCTGCGGGAGTCCAAGATCATCCATGTGGAATACTACCAAGAGGGAGAGATTTCCGAG
GGCTGCCTGCTCTTCAACAAGCCCACCCACTACAACAATGGCAACTATACCCTCATTGCC
AAAAACCCACTGGGCACAGCCAACCAGACCATCAATGGCCACTTCCTCAAGGAGCCCTTT
CCAGAGAGCACGGATAACTTTATCTTGTTTGACGAAGTGAGTCCCACACCTCCTATCACT
GTGACCCACAAACCAGAAGAAGACACTTTTGGGGTATCCATAGCAGTTGGACTTGCTGCT
TTTGCCTGTGTCCTGTTGGTGGTTCTCTTCGTCATGATCAACAAATATGGTCGACGGTCC
AAATTTGGAATGAAGGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCA
CTGCACCACATCAACCACGGCATCACCACGCCCTCGTCACTGGATGCGGGGCCCGACACT
GTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTACTTCCGTCAGGGA
CACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTG
AAGCGAGAACTGGGTGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTC
AGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCCACCCTGGCT
GCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATT
GTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATG
AAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTG
GATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCC
AGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTG
GCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACTTCGGCATG
TCCAGAGATGTCTACAGCACGGATTATTACAGGCTCTTTAATCCATCTGGAAATGATTTT
TGTATATGGTGTGAGGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAA
AGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTC
TGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGGAGGTCATT
GAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTAC
GATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATC
TACAAAATCCTCCATGCTTTGGGGAAGGCCACCCCAATCTACCTGGACATTCTTGGCTAG
>OriGene 5' read for NM_001012338 unedited
CTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCCGAATTCGGCACGAGGCTCCTC
TCCTCCTCCTCTTTTTTAGAAGCAGCGATCGGAGATGGATGTCTCTCTTTGCCCAGCCAA
GTGTAGTTTCTGGCGGATTTTCTTGCTGGGAAGCGTCTGGCTGGACTATGTGGGCTCCGT
GCTGGCTTGCCCTGCAAATTGTGTCTGCAGCAAGACTGAGATCAATTGCCGGCGGCCGGA
CGATGGGAACCTCTTCCCCCTCCTGGAAGGGCAGGATTCAGGGAACAGCAATGGGAACGC
CAGTATCAACATCACGGACATCTCAAGGAATATCACTTCCATACACATAGAGAACTGGCG
CAGTCTTCACACGCTCAACGCCGTGGACATGGAGCTCTACACCGGACTTCAAAAGCTGAC
CATCAAGAACTCAGGACTTCGGAGCATTCAGCCCAGAGCCTTTGCCAAGAACCCCCATTT
GCGTTATATAAACCTGTCAAGTAACCGGCTCACCACACTCTCGTGGCAGCTCTTCCAGAC
GCTGAGTCTTCGGGAATTGCAGTTGGAGCAGAACTTTNTCAACTGCAGCTGTGACATCCG
CTGGATGCAGCTCTGGCAGGAGCAGGGGGAGGCCAAGCTCACAGCCAGAACCTCTACTGC
ATCAACGCTGATGGCTNCCAGCTTNCTCTCTTTCGCATGAACATCAGTCAGTGTGACCTT
CCTGAGATCAGCGTGAGCCACGTCACCNTGACCGTACGAGAGGGTGACAATGCTGNTATC
ACTTGCATGGGCTCTGGATCACCCCTTNNCTGATGTGACTGGATAGTCACTGGGCTGCAG
TCATCAACACTCACCAGACAATCTGACTGGACCATGNTCATGCCCATCACTGAGCTGNTG
AATGTGACAAGTGAGACATGGGCTACCCCTGACTGCATGANAAAACGTGTGGCATGACAT
GCANTGTTGCCTACTGCACATTCCCCACTTGTAGCCTGAGAACTGACTGCCCTGACTGAT
TNATTTGGGG
>OriGene 3' read for NM_001012338 unedited
NNNNTTTTACTCTGAACCCGCGGCCGCATNCTAGGATCGAGTTTTTTTTTTTTTTTTTTC
CTTTTTTCAGTGTTGTATGTGTAGCAGGCACTTGAGTTTATATGAAGATGTTCGCTTCAG
TCAAGGATGGAAGGAGTTGTGAGGTGGAAGGGAGATGTGAGGCAGGGAGAGAGGAGGCAA
CAGAGTATGAATTCATGACCACCAGCCACCACTAGCCAAGAATGTCCAGGTAGATTGGGG
TGGCCTTCCCCAAAGCATGGAGGATTTTGTAGATCTCCTTGATGTTCAACCGCTGCTGTG
GTTCCCTCTGCCAGCACCCCAGCATGACATCGTACACCTCTTTGGGGCAGACTCGGGGCC
GCTCCAAAACACGACCTTGGGTAATGCACTCAATGACCTCCGTGTTTGAGAGTTGGAACC
ATGGCTGCTTTCCATAGGTGAAGATCTCCCAGAGGATCACCCCGAAGCTCCATACATCAC
TCTCTGTAGTGAACTTCCGGTACATGATGCTTTCAGGAGGCATCCAGCGAATGGGGAGCA
TGGTGTGTCCTCCCACCTCACACCATATACAAAAATCATTTCCAGATGGATTAAAGAGCC
TGNTATAATCCGTGCTGTAGACATCTCTGGACATGCCGAAGTCCCCAATCTTCACTAGCA
GATTCGCTCCAACCAGGCAGTTCCTGGTGGGGCCAGTCTCGTGCACAAAGTGCTGGGAGG
CCANGTACACCATACCCNGAGCGATCTGACTGGCATGTGNAGCATTTGGGAGAGCCCAGC
TCACCCTGGGCCTGNCGTGGCTGTCCATCCACAGGNATCATTGCATCTGGCCCATGGNCC
CNTGAGAAACTATCANGCCTNCATGCTNCATGTATTCAAAGACATGATAAGGGGGTCCCC
ATCGCCGCCACTT
Restriction Sites NotI-NotI     
ACCN NM_001012338
Insert Size 2710 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001012338.1, NP_001012338.1
RefSeq Size 3004 bp
RefSeq ORF 2520 bp
Locus ID 4916
Cytogenetics 15q25.3
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Neurotrophin signaling pathway
Gene Summary 'This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]'
Transcript Variant: This variant (1) encodes the longest isoform (a).

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