Aurora C (AURKC) (NM_001015878) Human Untagged Clone

CAT#: SC302003

AURKC (untagged)-Human aurora kinase C (AURKC), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AURKC
• Synonyms: AIE2; AIK3; ARK3; AurC; aurora-C; HEL-S-90; SPGF5; STK13
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001015878 edited
  ATGAGCTCCCCCAGAGCTGTGGTGCAGCTGGGCAAAGCTCAACCTGCAGGCGAAGAGTTG
  GCTACAGCAAACCAAACAGCCCAGCAGCCCAGCAGCCCAGCCATGCGGCGCCTCACAGTC
  GATGACTTTGAAATCGGGCGTCCCCTGGGCAAGGGGAAATTTGGGAATGTGTACCTGGCT
  CGGCTCAAGGAAAGCCATTTCATTGTGGCCCTGAAGGTTCTCTTCAAGTCGCAGATAGAG
  AAGGAAGGACTGGAGCACCAGCTGCGCCGGGAAATTGAGATCCAGGCTCATCTACAACAC
  CCCAATATCCTGCGCCTGTATAACTATTTCCATGATGCACGCCGGGTGTACCTGATTCTG
  GAATATGCTCCAAGGGGTGAGCTCTACAAGGAGCTGCAGAAAAGCGAGAAATTAGATGAA
  CAGCGCACAGCCACGATAATAGAGGAGTTGGCAGATGCCCTGACCTACTGCCATGACAAG
  AAAGTGATTCACAGAGATATTAAGCCAGAGAACCTGCTGCTGGGGTTCAGGGGTGAGGTG
  AAGATTGCAGATTTTGGCTGGTCTGTGCACACCCCCTCCCTGAGGAGGAAGACAATGTGT
  GGGACACTGGACTACTTGCCGCCAGAAATGATTGAGGGGAGAACATATGATGAAAAGGTG
  GATTTGTGGTGCATTGGAGTGCTCTGCTATGAGCTGCTGGTGGGATATCCACCCTTTGAG
  AGCGCCTCCCACAGTGAGACTTACAGACGCATCCTCAAGGTAGATGTGAGGTTTCCACTA
  TCAATGCCTCTGGGGGCCCGGGACTTGATTTCCAGGCTTCTCAGATACCAGCCCTTGGAG
  AGACTGCCCCTGGCCCAGATCCTGAAGCACCCCTGGGTTCAGGCCCACTCCCGAAGGGTG
  CTGCCTCCCTGTGCTCAGATGGCTTCCTGAGCCCTGTCTGCCTCTGTTCCCTTTGTGTGT
  GTTCAGGGAGCTCTCCTGGCTCTGCCACCTCATTTGTCTTTATTTTTTTCTCTTTTAAGA
  TGTAAGATGCTAATTAATAAAAGCTGAATCATTTCATACCAGCAAAAAAAAAAAAAAAAA
  ACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001015878 unedited
  CGCCAGCATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGATGAGCTC
  CCCCANAGCTGTGGTGCAGCTGGGCAAAGCTCAACCTGCAGGCGAAGAGTTGGCTACAGC
  AAACCAAACAGCCCAGCAGCCCAGCAGCCCAGCCATGCGGCGCCTCACAGTCGATGACTT
  TGAAATCGGGCGTCCCCTGGGCAAGGGGAAATTTGGGAATGTGTACCTGGCTCGGCTCAA
  GGAAAGCCATTTCATTGTGGCCCTGAAGGTTCTCTTCAAGTCGCAGATAGAGAAGGAAGG
  ACTGGAGCACCAGCTGCGCCGGGAAATTGAGATCCAGGCTCATCTACAACACCCCAATAT
  CCTGCGCCTGTATAACTATTTCCATGATGCACGCCGGGTGTACCTGATTCTGGAATATGC
  TCCAAGGGGTGAGCTCTACAAGGAGCTGCAGAAAAGCGAGAAATTAGATGAACAGCGCAC
  AGCCACGATAATAGAGGAGTTGGCAGATGCCCTGACCTACTGCCATGACAAGAAAGTGAT
  TCACAGAGATATTAAGCCAGAGAACCTGCTGCTGGGGTTCAGGGGTGAGGTGAAGATTGC
  AGATTTTGGCTGGTCTGTGCACACCCCCTCCCTGAGGAGGAAGACAATGTGTGGGACACT
  GGACTACTTGCCGCCAGAAATGATTGAGGGGAGAACATATGATGAAAAGGTGGATTTGTG
  GTGCATTGGAGTGCTCTGCTATGAGCTGCTGGTGGGATATCCACCCTTTGAGAGCGCCTC
  CCACAGTGAGACTTACAGACGCATCCTCAAGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001015878 unedited
  CCATCGGGGATGGCACTTCCGGGNCCAGNGNGAGCACTGGGGNGGGGTCACAGGGNTGCC
  ACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTT
  TTTTTTTTTTTTGCTGGTATGAAATGATTCAGCTTTTATTAATTAGCATCTTACATCTTA
  AAAGAGAAAAAAATAAAGACAAATGAGGTGGCAGAGCCAGGAGAGCTCCCTGAACACACA
  CAAAGGGAACAGAGGCAGACAGGGCTCAGGAAGCCATCTGAGCACAGGGAGGCAGCACCC
  TTCGGGAGTGGGCCTGAACCCAGGGGTGCTTCAGGATCTGGGCCAGGGGCAGTCTCTCCA
  AGGGCTGGTATCTGAGAAGCCTGGAAATCAAGTCCCGGGCCCCCAGAGGCATTGATAGTG
  GAAACCTCACATCTACCTTGAGGATGCGTCTGTAAGTCTCACTGTGGGAGGCGCTCTCAA
  AGGGTGGATATCCCACCAGCAGCTCATAGCAGAGCACTCCAATGCACCACAAATCCACCT
  TTTCATCATATGTTCTCCCCTCAATCATTTCTGGCGGCAAGTAGTCCAGTGTCCCACACA
  TTGTCTTCCTCCTCAGGGAGGGGGTGTGCACAGACCAGCCAAAATCTGCAATCTTCACCT
  CACCCCTGAACCCCAGCAGCAGGTTCTCTGGCTTAATATCTCTGTGAATCACTTTCTTGT
  CATGGCAGTAGGTCAGGGCATCTGCCAACTCCTCTATTATCGTGGCTGTGCGCTGTTCAT
  CTAATTTCTCGCTTTTCTGCAGCTCCCTGTAAAGCTCACCCCTTTGGAGCT
  
• Restriction Sites: Please inquire
• ACCN: NM_001015878
• Insert Size: 1100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001015878.1, NP_001015878.1
• RefSeq Size: 1261 bp
• RefSeq ORF: 930 bp
• Locus ID: 6795
• Cytogenetics: 19q13.43
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: 'This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) encodes the longest isoform (1).