SH3KBP1 (NM_001024666) Human Untagged Clone

CAT#: SC302281

SH3KBP1 (untagged)-Human SH3-domain kinase binding protein 1 (SH3KBP1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SH3KBP1
• Synonyms: AGMX2; CD2BP3; CIN85; GIG10; HSB-1; HSB1; IMD61; MIG18
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001024666, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGGTTTCAGCAGCCAAAGCCCCAAGTGCCGCAGACTTGTCTGAGATTGAAATAAAGAAAGAGATGA
  AGAAAGACCCTCTCACCAACAAAGCTCCAGAAAAGCCCCTGCACGAAGTGCCCAGTGGAAACTCTTTGCT
  GTCTTCTGAAACGATTTTAAGAACCAATAAGAGAGGCGAGCGACGGAGGCGCCGGTGCCAGGTGGCATTC
  AGCTACCTGCCCCAGAATGACGATGAACTTGAGCTGAAAGTTGGCGACATCATAGAGGTGGTAGGAGAGG
  TAGAGGAAGGATGGTGGGAAGGTGTTCTCAACGGGAAGACTGGAATGTTTCCTTCCAACTTCATCAAGGA
  GCTGTCAGGGGAGTCGGATGAGCTTGGCATTTCCCAGGATGAGCAGCTATCCAAGTCAAGTTTAAGGGAA
  ACCACAGGCTCCGAGAGTGATGGGGGTGACTCAAGCAGCACCAAGTCTGAAGGTGCCAACGGGACAGTGG
  CAACTGCAGCAATCCAGCCCAAGAAAGTTAAGGGAGTGGGCTTTGGAGACATTTTCAAAGACAAGCCAAT
  CAAACTAAGACCAAGGTCAATTGAAGTAGAAAATGACTTTCTGCCGGTAGAAAAGACTATTGGGAAGAAG
  TTACCTGCAACTACAGCAACTCCAGACTCATCAAAAACAGAAATGGACAGCAGGACAAAGAGCAAGGATT
  ACTGCAAAGTAATATTTCCATATGAGGCACAGAATGATGATGAATTGACAATCAAAGAAGGAGATATAGT
  CACTCTCATCAATAAGGACTGCATCGACGTAGGCTGGTGGGAAGGAGAGCTGAACGGCAGACGAGGCGTG
  TTCCCCGATAACTTCGTGAAGTTACTTCCACCGGACTTTGAAAAGGAAGGGAATAGACCCAAGAAGCCAC
  CGCCTCCATCCGCTCCTGTCATCAAACAAGGGGCAGGCACCACTGAGAGAAAACATGAAATTAAAAAGAT
  ACCTCCTGAAAGACCAGAAATGCTTCCAAACAGAACAGAAGAAAAAGAAAGACCAGAGAGAGAGCCAAAA
  CTGGATTTACAGAAGCCCTCCGTTCCTGCCATACCGCCAAAAAAGCCTCGGCCACCTAAGACCAATTCTC
  TCAGCAGACCTGGCGCACTGCCCCCGAGAAGGCCGGAGAGACCGGTGGGTCCGCTGACACACACCAGGGG
  TGACAGTCCAAAGATTGACTTGGCCGGCAGTTCGCTATCTGGCATCCTGGACAAAGATCTCTCGGACCGC
  AGCAATGACATTGACTTAGAAGGTTTTGACTCCGTGGTATCATCTACTGAGAAACTCAGTCATCCGACCA
  CAAGCAGACCAAAAGCTACAGGGAGGCGGCCTCCGTCCCAGTCCCTCACATCTTCATCCCTTTCAAGCCC
  TGATATCTTCGACTCCCCAAGTCCCGAAGAGGATAAGGAGGAACACATTTCACTTGCGCACAGAGGAGTG
  GACGCGTCAAAGAAAACTTCCAAGACTGTTACCATATCCCAAGTGTCTGACAACAAAGCATCCCTGCCGC
  CCAAGCCGGGGACCATGGCAGCAGGTGGCGGTGGGCCAGCCCCTCTGTCCTCAGCGGCGCCCTCCCCCCT
  GTCATCCTCTTTGGGAACAGCTGGACACAGAGCCAACTCCCCGTCTCTGTTCGGCACGGAAGGAAAACCA
  AAGATGGAGCCTGCGGCCAGCAGCCAGGCGGCCGTGGAGGAGCTAAGGACACAGGTCCGCGAGCTGAGGA
  GCATCATCGAGACCATGAAGGACCAGCAGAAACGAGAGATTAAACAGTTATTGTCTGAGTTGGATGAAGA
  GAAGAAAATCCGGCTTCGGTTGCAGATGGAAGTGAACGACATAAAGAAAGCTCTACAATCAAAATGA
  
  
• Restriction Sites: SgfI-NotI
• ACCN: NM_001024666
• ORF Size: 1887 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001024666.2, NP_001019837.1
• RefSeq Size: 4454
• RefSeq ORF: 1887
• Locus ID: 30011
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis
• Gene Summary: This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform 1.