IL9R (NM_002186) Human Untagged Clone

CAT#: SC303142

IL9R (untagged)-Human interleukin 9 receptor (IL9R), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL9R
• Synonyms: CD129; IL-9R
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_002186, the custom clone sequence may differ by one or more nucleotides
  ATGGGACTGGGCAGATGCATCTGGGAAGGCTGGACCTTGGAGAGTGAGGCCCTGAGGCGA
  GACATGGGCACCTGGCTCCTGGCCTGCATCTGCATCTGCACCTGTGTCTGCTTGGGAGTC
  TCTGTCACAGGGGAAGGACAAGGGCCAAGGTCTAGAACCTTCACCTGCCTCACCAACAAC
  ATTCTCAGGATCGATTGCCACTGGTCTGCCCCAGAGCTGGGACAGGGCTCCAGCCCCTGG
  CTCCTCTTCACCAGCAACCAGGCTCCTGGCGGCACACATAAGTGCATCTTGCGGGGCAGT
  GAGTGCACCGTCGTGCTGCCACCTGAGGCAGTGCTCGTGCCATCTGACAATTTCACCATC
  ACTTTCCACCACTGCATGTCTGGGAGGGAGCAGGTCAGCCTGGTGGACCCGGAGTACCTG
  CCCCGGAGACACGTTAAGCTGGACCCGCCCTCTGACTTGCAGAGCAACATCAGTTCTGGC
  CACTGCATCCTGACCTGGAGCATCAGTCCTGCCTTGGAGCCAATGACCACACTTCTCAGC
  TATGAGCTGGCCTTCAAGAAGCAGGAAGAGGCCTGGGAGCAGGCCCAGCACAGGGATCAC
  ATTGTCGGGGTGACCTGGCTTATACTTGAAGCCTTTGAGCTGGACCCTGGCTTTATCCAT
  GAGGCCAGGCTGCGTGTCCAGATGGCCACACTGGAGGATGATGTGGTAGAGGAGGAGCGT
  TATACAGGCCAGTGGAGTGAGTGGAGCCAGCCTGTGTGCTTCCAGGCTCCCCAGAGACAA
  GGCCCTCTGATCCCACCCTGGGGGTGGCCAGGCAACACCCTTGTTGCTGTGTCCATCTTT
  CTCCTGCTGACTGGCCCGACCTACCTCCTGTTCAAGCTGTCGCCCAGGGTGAAGAGAATC
  TTCTACCAGAACGTGCCCTCTCCAGCGATGTTCTTCCAGCCCCTCTACAGTGTACACAAT
  GGGAACTTCCAGACTTGGATGGGGGCCCACGGGGCCGGTGTGCTGTTGAGCCAGGACTGT
  GCTGGCACCCCACAGGGAGCCTTGGAGCCCTGCGTCCAGGAGGCCACTGCACTGCTCACT
  TGTGGCCCAGCGCGTCCTTGGAAATCTGTGGCCCTGGAGGAGGAACAGGAGGGCCCTGGG
  ACCAGGCTCCCGGGGAACCTGAGCTCAGAGGATGTGCTGCCAGCAGGGTGTACGGAGTGG
  AGGGTACAGACGCTTGCCTATCTGCCACAGGAGGACTGGGCCCCCACGTCCCTGACTAGG
  CCGGCTCCCCCAGACTCAGAGGGCAGCAGGAGCAGCAGCAGCAGCAGCAGCAGCAACAAC
  AACAACTACTGTGCCTTGGGCTGCTATGGGGGATGGCACCTCTCAGCCCTCCCAGGAAAC
  ACACAGAGCTCTGGGCCCATCCCAGCCCTGGCCTGTGGCCTTTCTTGTGACCATCAGGGC
  CTGGAGACCCAGCAAGGAGTTGCCTGGGTGCTGGCTGGTCACTGCCAGAGGCCTGGGCTG
  CATGAGGACCTCCAGGGCATGTTGCTCCCTTCTGTCCTCAGCAAGGCTCGGTCCTGGACA
  TTCTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_002186
• ORF Size: 1566 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_002186.2, NP_002177.2
• RefSeq Size: 2171
• RefSeq ORF: 1566
• Locus ID: 3581
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway
• Gene Summary: The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (1).