Integrin alpha 3 (ITGA3) (NM_002204) Human Untagged Clone

CAT#: SC303147

ITGA3 (untagged)-Human integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ITGA3), transcript variant a


  "NM_002204" in other vectors (6)

Reconstitution Protocol

USD 1,100.00

4 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ITGA3
Synonyms CD49C; FRP-2; GAP-B3; GAPB3; ILNEB; MSK18; VCA-2; VL3A; VLA3a
Vector pCMV6-XL6
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_002204 edited
ATGGGCCCCGGCCCCAGCCGCGCGCCCCGCGCCCCACGCCTGATGCTCTGTGCGCTCGCC
TTGATGGTGGCGGCCGGCGGCTGCGTCGTCTCCGCCTTCAACCTGGATACCCGATTCCTG
GTAGTGAAGGAGGCCGGGAACCCGGGCAGCCTCTTCGGCTACTCGGTCGCCCTCCATCGG
CAGACAGAGCGGCAGCAGCGCTACCTGCTCCTGGCTGGTGCCCCCCGGGAGCTCGCTGTG
CCCGATGGCTACACCAACCGGACTGGTGCTGTGTACCTGTGCCCACTCACTGCCCACAAG
GATGACTGTGAGCGGATGAACATCACAGTGAAAAATGACCCTGGCCATCACATTATTGAG
GACATGTGGCTTGGAGTGACTGTGGCCAGCCAGGGCCCTGCAGGCAGAGTTCTGGTCTGT
GCCCACCGCTACACCCAGGTGCTGTGGTCAGGGTCAGAAGACCAGCGGCGCATGGTGGGC
AAGTGCTACGTGCGAGGCAATGACCTAGAGCTGGACTCCAGTGATGACTGGCAGACCTAC
CACAACGAGATGTGCAATAGCAACACAGACTACCTGGAGACGGGCATGTGCCAGCTGGGC
ACCAGCGGTGGCTTCACCCAGAACACTGTGTACTTCGGCGCCCCCGGTGCCTACAACTGG
AAAGGAAACAGCTACATGATTCAGCGCAAGGAGTGGGACTTATCTGAGTATAGTTACAAG
GACCCAGAGGACCAAGGAAACCTCTATATTGGGTACACGATGCAGGTAGGCAGCTTCATC
CTGCACCCCAAAAACATCACCATTGTGACAGGTGCCCCACGGCACCGACATATGGGCGCG
GTGTTCTTGCTGAGCCAGGAGGCAGGCGGAGACCTGCGGAGGAGGCAGGTGCTGGAGGGC
TCGCAGGTGGGCGCCTATTTTGGCAGCGCAATTGCCCTGGCAGACCTGAACAATGATGGG
TGGCAGGACCTCCTGGTGGGCGCCCCCTACTACTTCGAGAGGAAAGAGGAAGTAGGGGGT
GCCATCTATGTCTTCATGAACCAGGCGGGAACCTCCTTCCCTGCTCACCCCTCACTCCTT
CTTCATGGCCCCAGTGGCTCTGCCTTTGGTTTATCTGTGGCCAGCATTGGTGACATCAAC
CAGGATGGATTTCAGGATATTGCTGTGGGAGCTCCGTTTGAAGGCTTGGGCAAAGTGTAC
ATCTATCACAGTAGCTCTAAGGGGCTCCTTAGACAGCCCCAGCAGGTAATCCATGGAGAG
AAGCTGGGACTGCCTGGGTTGGCCACCTTCGGCTATTCCCTCAGTGGGCAGATGGATGTG
GATGAGAACTTCTACCCAGACCTTCTAGTGGGAAGCCTGTCAGACCACATTGTGCTGCTG
CGGGCCCGGCCAGTCATCAACATCGTCCACAAGACCTTGGTGCCCAGGCCAGCTGTGCTG
GACCCTGCACTTTGCACGGCCACCTCTTGTGTGCAAGTGGAGCTGTGCTTTGCTTACAAC
CAGAGTGCCGGGAACCCCAACTACAGGCGAAACATCACCCTGGCCTACACTCTGGAGGCT
GACAGGGACCGCCGGCCGCCCCGGCTCCGCTTTGCCGGCAGTGAGTCCGCTGTCTTCCAC
GGCTTCTTCTCCATGCCCGAGATGCGCTGCCAGAAGCTGGAGCTGCTCCTGATGGACAAC
CTCCGTGACAAACTCCGCCCCATCATCATCTCCATGAACTACTCTTTACCTTTGCGGATG
CCCGATCGCCCCCGGCTGGGGCTGCGGTCCCTGGACGCCTACCCGATCCTCAACCAGGCA
CAGGCTCTGGAGAACCACACTGAGGTCCAGTTCCAGAAGGAGTGCGGGCCTGACAACAAG
TGTGAGAGCAACTTGCAGATGCGGGCAGCCTTCGTGTCAGAGCAGCAGCAGAAGCTGAGC
AGGCTCCAGTACAGCAGAGACGTCCGGAAATTGCTCCTGAGCATCAACGTGACGAACACC
CGGACCTCGGAGCGCTCCGGGGAGGACGCCCACGAGGCGCTGCTCACCCTGGTGGTGCCT
CCCGCCCTGCTGCTGTCCTCAGTGCGCCCCCCCGGGGCCTGCCAAGCTAATGAGACCATC
TTTTGCGAGCTGGGGAACCCCTTCAAACGGAACCAGAGGATGGAGCTGCTCATCACCTTT
GAGGTCATCGGGGTGACCCTGCACACAAGGGACCTTCAGGTGCAGCTGCAGCTCTCCACG
TCGAGTCACCAGGACAACCTGTGGCCCATGATCCTCACTCTGCTGGTGGACTATACACTC
CAGACCTCGCTTAGCATGGTAAATCACCGGCTACAAAGCTTCTTTGGGGGGACAGTGATG
GGTGAGTCTGGCATGAAAACTGTGGAGGATGTAGGAAGCCCCCTCAAGTATGAATTCCAG
GTGGGCCCAATGGGGGAGGGGCTGGTGGGCCTGGGGACCCTGGTCCTAGGTCTGGAGTGG
CCCTACGAAGTCAGCAATGGCAAGTGGCTGCTGTATCCCACGGAGATCACCGTCCATGGC
AATGGGTCCTGGCCCTGCCGACCACCTGGAGACCTTATCAACCCTCTCAACCTCACTCTT
TCTGACCCTGGGGACAGGCCATCATCCCCACAGCGCAGGCGGCGACAGCTGGATCCAGGG
GGAGGCCAGGGCCCCCCACCTGTCACTCTGGCTGCTGCCAAAAAAGCCAAGTCTGAGACT
GTGCTGACCTGTGCCACAGGGCGTGCCCACTGTGTGTGGCTAGAGTGCCCCATCCCTGAT
GCCCCCGTTGTCACCAACGTGACTGTGAAGGCACGAGTGTGGAACAGCACCTTCATCGAG
GATTACAGAGACTTTGACCGAGTCCGGGTAAATGGCTGGGCTACCCTATTCCTCCGAACC
AGCATCCCCACCATCAACATGGAGAACAAGACCACGTGGTTCTCTGTGGACATTGACTCG
GAGCTGGTGGAGGAGCTGCCGGCCGAAATCGAGCTGTGGCTGGTGCTGGTGGCCGTGGGT
GCAGGGCTGCTGCTGCTGGGGCTGATCATCCTCCTGCTGTGGAAGTGCGGCTTCTTCAAG
CGAGCCCGCACTCGCGCCCTGTATGAAGCTAAGAGGCAGAAGGCGGAGATGAAGAGCCAG
CCGTCAGAGACAGAGAGGCTGACCGACGACTACTGA
Restriction Sites NotI-NotI     
ACCN NM_002204
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by a single amino acid.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002204.1, NP_002195.1
RefSeq Size 4637 bp
RefSeq ORF 3156 bp
Locus ID 3675
Cytogenetics 17q21.33
Protein Families Druggable Genome, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer
Gene Summary 'The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.