Gemin 2 (GEMIN2) (NM_003616) Human Untagged Clone

CAT#: SC303357

GEMIN2 (untagged)-Human survival of motor neuron protein interacting protein 1 (SIP1), transcript variant alpha

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GEMIN2
• Synonyms: SIP1; SIP1-delta
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003616 edited
  GCATGCGCCGAGCGGAACTGGCTGGTTTGAAAACCATGGCGTGGGTACCAGCGGAGTCCG
  CAGTGGAAGAGTTGATGCCTCGGCTATTGCCGGTAGAGCCTTGCGACTTGACGGAAGGTT
  TCGATCCCTCGGTACCCCCGAGGACGCCTCAGGAATACCTGAGGCGGGTCCAGATCGAAG
  CAGCTCAATGTCCAGATGTTGTGGTAGCTCAAATTGACCCAAAGAAGTTGAAAAGGAAGC
  AAAGTGTGAATATTTCTCTTTCAGGATGCCAACCCGCCCCTGAAGGTTATTCCCCAACAC
  TTCAATGGCAACAGCAACAAGTGGCACAGTTTTCAACTGTTCGACAGAATGTGAACAAAC
  ATAGAAGTCACTGGAAATCACAACAGTTGGATAGTAATGTGACAATGCCAAAATCTGAAG
  ATGAAGAAGGCTGGAAGAAATTTTGTCTGGGTGAAAAGTTATGTGCTGACGGGGCTGTTG
  GACCAGCCACAAATGAAAGTCCTGGAATAGATTATGTACAAATTGGTTTTCCTCCCTTGC
  TTAGTATTGTTAGCAGAATGAATCAGGCAACAGTAACTAGTGTCTTGGAATATCTGAGTA
  ATTGGTTTGGAGAAAGAGACTTTACTCCAGAATTGGGAAGATGGCTTTATGCTTTATTGG
  CTTGTCTTGAAAAGCCTTTGTTACCTGAGGCTCATTCACTGATTCGGCAGCTTGCAAGAA
  GGTGCTCTGAAGTGAGGCTCTTAGTGGATAGCAAAGATGATGAGAGGGTTCCTGCTTTGA
  ATTTATTAATCTGCTTGGTTAGCAGGTATTTTGACCAACGTGATTTAGCTGATGAGCCAT
  CTTGATGTAGCTGATCTCTCAGGGATAGAAGATATTTCTCATGAAGGCAGCCTAACTCTG
  AGGAAAACAATGCCAATTCAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003616 unedited
  GTGCCTTTGTATACGACTCCTATAGGGCGGCCGCGTACTTCGCCCTTGCATGCGCCGAGC
  GGAACTGGCTGGTTTGAAAACCATGGCGTGGGTACCAGCGGAGTCCGCAGTGGAAGAGTT
  GATGCCTCGGCTATTGCCGGTAGAGCCTTGCGACTTGACGGAAGGTTTCGATCCCTCGGT
  ACCCCCGAGGACGCCTCAGGAATACCTGAGGCGGGTCCAGATCGAAGCAGCTCAATGTCC
  AGATGTTGTGGTAGCTCAAATTGACCCAAAGAAGTTGAAAAGGAAGCAAAGTGTGAATAT
  TTCTCTTTCAGGATGCCAACCCGCCCCTGAAGGTTATTCCCCAACACTTCAATGGCAACA
  GCAACAAGTGGCACAGTTTTCAACTGTTCGACAGAATGTGAACAAACATAGAAGTCACTG
  GAAATCACAACAGTTGGATAGTAATGTGACAATGCCAAAATCTGAAGATGAAGAAGGCTG
  GAAGAAATTTTGTCTGGGTGAAAAGTTATGTGCTGACGGGGCTGTTGGACCAGCCACAAA
  TGAAAGTCCTGGAATAGATTATGTACAAATTGGTTTTCCTCCCTTGCTTAGTATTGTTAG
  CAGAATGAATCAGGCAACAGTAACTAGTGTCTTGGAATATCTGAGTAATTGGTTTGGAGA
  AAGAGACTTTACTCCAGAATTGGGAAGATGGCTTTATGCTTTATTGGCTTGTCTTGAAAA
  GCCTTTGTTACCTGAGGCTCATTCACTGATTCGGCAGCTTGCAAGAAGGTGCTCTGAAGT
  GAGGCTCTTAGTGGATAGCAAGATGATGAGAGGGTTTCCTGCTTTGAATTTATTAATCTG
  CTTGGTTAGCAGGTATTTTGACCAACGTGATTTAGCTGATGAGCCATCTTGATGTAGCTG
  ATCTCTCAGGGATAGAAAGAATATTTTCTCATGAAGGCAGCCTAACCTTCTGGAGGAAAA
  AACAATGGCA
  
• Restriction Sites: Please inquire
• ACCN: NM_003616
• ORF Size: 843 bp
• Insert Size: 900
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_003616.2, NP_003607.1
• RefSeq Size: 1368
• RefSeq ORF: 843
• Locus ID: 8487
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Gene Summary: This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (alpha) represents the longest transcript and encodes the longest isoform (alpha).