LIPF (NM_004190) Human Untagged Clone

CAT#: SC303449

LIPF (untagged)-Human lipase, gastric (LIPF), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LIPF
• Synonyms: GL; HGL; HLAL
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004190, RT-PCR generated
  AAATGTGGCTGCTTTTAACAATGGCAAGTTTGATATCTGTACTGGGGACTACACATGGTT
  TGTTTGGAAAATTACATCCTGGAAGCCCTGAAGTGACTATGAACATTAGTCAGATGATTA
  CTTATTGGGGATACCCAAATGAAGAATATGAAGTTGTGACTGAAGATGGTTATATTCTTG
  AAGTCAATAGAATTCCTTATGGGAAGAAAAATTCAGGGAATACAGGCCAGAGACCTGTTG
  TGTTTTTGCAGCATGGTTTGCTTGCATCAGCCACAAACTGGATTTCCAACCTGCCGAACA
  ACAGCCTTGCCTTCATTCTGGCAGATGCTGGTTATGATGTGTGGCTGGGCAACAGCAGAG
  GAAACACCTGGGCCAGAAGAAACTTGTACTATTCACCAGATTCAGTTGAATTCTGGGCTT
  TCAGCTTTGATGAAATGGCTAAATATGACCTTCCAGCCACAATCGACTTCATTGTAAAGA
  AAACTGGACAGAAGCAGCTACACTATGTTGGCCATTCCCAGGGCACCACCATTGGTTTTA
  TTGCCTTTTCCACCAATCCCAGCCTGGCTAAAAGAATCAAAACCTTCTATGCTCTAGCTC
  CTGTTGCCACTGTGAAGTATACAAAAAGCCTTATAAACAAACTTAGATTTGTTCCTCAAT
  CCCTCTTCAAGTTTATATTTGGTGACAAAATATTCTACCCACACAACTTCTTTGATCAAT
  TTCTTGCTACTGAAGTGTGCTCCCGTGAGATGCTGAATCTCCTTTGCAGCAATGCCTTAT
  TTATAATTTGTGGATTTGACAGTAAGAACTTTAACACGAGTCGCTTGGATGTGTATCTAT
  CACATAATCCAGCAGGAACTTCTGTTCAAAACATGTTCCATTGGACCCAGGCTGTTAAGT
  CTGGGAAATTCCAAGCTTATGACTGGGGAAGCCCAGTTCAGAATAGGATGCACTATGATC
  AGTCCCAACCTCCCTACTACAATGTGACAGCCATGAATGTACCAATTGCAGTGTGGAACG
  GTGGCAAGGACCTGTTGGCTGACCCCCAAGATGTTGGCCTTTTGCTTCCAAAACTCCCCA
  ATCTTATTTACCACAAGGAGATTCCTTTTTACAATCACTTGGACTTTATCTGGGCAATGG
  ATGCCCCTCAAGAAGTTTACAATGACATTGTTTCTATGATATCAGAAGATAAAAAGTAGT
  TCTGGATTTAAAGAATTATCCGTTTGTTTTT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004190 unedited
  NNNNNNAAGTTCACTATTGTATACGACTCCTATAGGCGGCCGCGNATTCAGATCTGGTAC
  CAAATGTGGCTGCTTTTAACAATGGCAAGTTTGATATCTGTACTGGGGACTACACATGGT
  TTGTTTGGAAAATTACATCCTGGAAGCCCTGAAGTGACTATGAACATTAGTCAGATGATT
  ACTTATTGGGGATACCCAAATGAAGAATATGAAGTTGTGACTGAAGATGGTTATATTCTT
  GAAGTCAATAGAATTCCTTATGGGAAGAAAAATTCAGGGAATACAGGCCAGAGACCTGTT
  GTGTTTTTGCAGCATGGTTTGCTTGCATCAGCCACAAACTGGATTTCCAACCTGCCGAAC
  AACAGCCTTGCCTTCATTCTGGCAGATGCTGGTTATGATGTGTGGCTGGGCAACAGCAGA
  GGAAACACCTGGGCCAGAAGAAACTTGTACTATTCACCAGATTCAGTTGAATTCTGGGCT
  TTCAGCTTTGATGAAATGGCTAAATATGACCTTCCAGCCACAATCGACTTCATTGTAAAG
  AAAACTGGACAGAAGCAGCTACACTATGTTGGCCATTCCCAGGGCACCACCATTGGGTTT
  TATTGCCTTTTCCACCAATCCCAGCCTGGCTAAAAGAATCAAAACCTTCTATGCTCTAGC
  TCCTGTTGCCACTGTGAAGTATACAAAAAGCCTTATAAACAAACTTAGNATTTGTTCCTC
  AATCCCTCTTCAAGTTTATTATTTGGTGACAAAATATTCTACCCACACAACTTCTTTGAT
  CAATTTCTTGCTACTGGAAGTGTGCTCCCGTGAGATGCTGAATCTCCTTTGCAGCAATGC
  CTTATTTATAATTTGGTGGATTTGACAGTAAGAACTTTAACACGAGTCGTTTGGGGATGT
  GTAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004190 unedited
  NNCCATTGGNGAATGGCACTTNCCAGGNCCAGNANAGCACTGGGGNAGGGTCACAGGNAT
  GCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTT
  GNGAAAAACAAACGGATAATTCTTTAAATCCAGAACTACTTTTTATCTTCTGATATCATA
  GAAACAATGTCATTGTAAACTTCTTGAGGGGCATCCATTGCCCAGATAAAGTCCAAGTGA
  TTGTAAAAAGGAATCTCCTTGTGGTAAATAAGATTGGGGAGTTTTGGAAGCAAAAGGCCA
  ACATCTTGGGGGTCAGCCAACAGGTCCTTGCCACCGTTCCACACTGCAATTGGTACATTC
  ATGGCTGTCACATTGTAGTAGGGAGGTTGGGACTGATCATAGTGCATCCTATTCTGAACT
  GGGCTTCCCCAGTCATAAGCTTGGAATTTCCCAGACTTAACAGCCTGNGTCCAATGGAAC
  ATGTTTTGAACAGAAGTTCCTGCTGGATTATGTGATAGATACACATCCAAGCGACTCGTG
  TTAAAGTTCTTACTGTCAAATCCACAAATTATAAATAAGGCATTGCTGCANAGGAGATTC
  AGCATCTCACGGGAGCACACTTCAGTAGCAAGAAATTGATCAAAGAAAAGTTGTGTGGGT
  AGAAATATTTTGTCACCAAATATAAACTTGAAGAGGGGATTGAGGAACANATCTAAAGGT
  TTGTTAATAAGGCTTTTTGTATACTTCACAGTGGCAACAGGAGCTAGACCTAANAAAGGT
  TTTGATTCTTTTTACCAGGCTGGGATTGGGGGGAAAAGGCAATAAACCAATGGTTGGTGC
  CCTGGGAATGGNCCACATAGTGTAACTGGCTCTGTCCCGGTTTCTTACAATGAAATCGAT
  GTGGCTGGGG
  
• Restriction Sites: Please inquire
• ACCN: NM_004190
• ORF Size: 1197 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This construct is a cloned PCR fragment that was fully sequenced. There are no nucleotide differences between the OriGene clone and the NCBI reference ORF.

Reference Data

• RefSeq: NM_004190.1, NP_004181.1
• RefSeq Size: 1365
• RefSeq ORF: 1197
• Locus ID: 8513
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Glycerolipid metabolism, Metabolic pathways
• Gene Summary: This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
  Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.