MUC4 (NM_004532) Human Untagged Clone

CAT#: SC303494

MUC4 (untagged)-Human mucin 4, cell surface associated (MUC4), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MUC4
• Synonyms: ASGP; HSA276359; MUC-4
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_004532, the custom clone sequence may differ by one or more nucleotides
  ATGAAGGGGGCACGCTGGAGGAGGGTCCCCTGGGTGTCCCTGAGCTGCCTGTGTCTCTGC
  CTCCTTCCGCATGTGGTCCCAGGAATGACAACACCGTCACTGAAGACAGACGGTGGGAGA
  CGCACAGCCACATCACCACCCCCCACAACCTCCCAGACCATCATTTCCACCATTCCCAGC
  ACTGCCATGCACACCCGCTCCACAGCTGCCCCCATCCCCATCCTGCCTGAGAGAGGAGTT
  TCCCTCTTCCCCTATGGGGCAGGCGCCGGGGACCTGGAGTTCGTCAGGAGGACCGTGGAC
  TTCACCTCCCCACTCTTCAAGCCGGCGACTGGCTTCCCCCTTGGCTCCTCTCTCCGTGAT
  TCCCTCTACTTCACAGACAATGGCCAGATCATCTTCCCAGAGTCAGACTACCAGATTTTC
  TCCTACCCCAACCCACTCCCAACAGGCTTCACAGGCCGGGACCCTGTGGCCCTGGTGGCT
  CCGTTCTGGGACGATGCTGACTTCTCCACTGGTCGGGGGACCACATTTTATCAGGAATAC
  GAGACGTTCTATGGTGAACACAGCCTGCTAGTCCAGCAGGCCGAGTCTTGGATTAGAAAG
  ATGACAAACAACGGGGGCTACAAGGCCAGGTGGGCCCTAAAGGTCACGTGGGTCAATGCC
  CACGCCTATCCTGCCCAGTGGACCCTCGGGAGCAACACCTACCAAGCCATCCTCTCCACG
  GACGGGAGCAGGTCCTATGCCCTGTTTCTCTACCAGAGCGGTGGGATGCAGTGGGACGTG
  GCCCAGCGCTCAGGCAACCCGGTGCTCATGGGCTTCTCTAGTGGAGATGGCTATTTCGAA
  AACAGCCCACTGATGTCCCAGCCAGTGTGGGAGAGGTATCGCCCTGATAGATTCCTGAAT
  TCCAACTCAGGCCTCCAAGGGCTGCAGTTCTACAGGCTACACCGGGAAGAAAGGCCCAAC
  TACCGTCTCGAGTGCCTGCAGTGGCTGAAGAGCCAGCCTCGGTGGCCCAGCTGGGGCTGG
  AACCAGGTCTCCTGCCCTTGTTCCTGGCAGCAGGGACGACGGGACTTACGATTCCAACCC
  GTCAGCATAGGTCGCTGGGGCCTCGGCAGTAGGCAGCTGTGCAGCTTCACCTCTTGGCGA
  GGAGGCGTGTGCTGCAGCTACGGGCCCTGGGGAGAGTTTCGTGAAGGCTGGCACGTGCAG
  CGTCCTTGGCAGTTGGCCCAGGAACTGGAGCCACAGAGCTGGTGCTGCCGCTGGAATGAC
  AAGCCCTACCTCTGTGCCCTGTACCAGCAGAGGCGGCCCCACGTGGGCTGTGCTACATAC
  AGGCCCCCACAGCCCGCCTGGATGTTCGGGGACCCCCACATCACCACCTTGGATGGTGTC
  AGTTACACCTTCAATGGGCTGGGGGACTTCCTGCTGGTCGGGGCCCAAGACGGGAACTCC
  TCCTTCCTGCTTCAGGGCCGCACCGCCCAGACTGGCTCAGCCCAGGCCACCAACTTCATC
  GCCTTTGCGGCTCAGTACCGCTCCAGCAGCCTGGGCCCCGTCACGGTCCAATGGCTCCTT
  GAGCCTCACGACGCAATCCGTGTCCTGCTGGATAACCAGACTGTGACATTTCAGCCTGAC
  CATGAAGACGGCGGAGGCCAGGAGACGTTCAACGCCACCGGAGTCCTCCTGAGCCGCAAC
  GGCTCTGAGGTCTCGGCCAGCTTCGACGGCTGGGCCACCGTCTCGGTGATCGCGCTCTCC
  AACATCCTCCACGCCTCCGCCAGCCTCCCGCCCGAGTACCAGAACCGCACGGAGGGGCTC
  CTGGGGGTCTGGAATAACAATCCAGAGGACGACTTCAGGATGCCCAATGGCTCCACCATT
  CCCCCAGGGAGCCCTGAGGAGATGCTTTTCCACTTTGGAATGACCTGGCAGATCAACGGG
  ACAGGCCTCCTTGGCAAGAGGAATGACCAGCTGCCTTCCAACTTCACCCCTGTTTTCTAC
  TCACAACTGCAAAAAAACAGCTCCTGGGCTGAACATTTGATCTCCAACTGTGACGGAGAT
  AGCTCATGCATCTATGACACCCTGGCCCTGCGCAACGCAAGCATCGGACTTCACACGAGG
  GAAGTCAGTAAAAACTACGAGCAGGCGAACGCCACCCTCAATCAGTACCCGCCCTCCATC
  AATGGTGGTCGTGTGATTGAAGCCTACAAGGGGCAGACCACGCTGATTCAGTACACCAGC
  AATGCTGAGGATGCCAACTTCACGCTCAGAGACAGCTGCACCGACTTGGAGCTCTTTGAG
  AATGGGACGTTGCTGTGGACACCCAAGTCGCTGGAGCCATTCACTCTGGAGATTCTAGCA
  AGAAGTGCCAAGATTGGCTTGGCATCTGCACTCCAGCCCAGGACTGTGGTCTGCCATTGC
  AATGCAGAGAGCCAGTGTTTGTACAATCAGACCAGCAGGGTGGGCAACTCCTCCCTGGAG
  GTGGCTGGCTGCAAGTGTGACGGGGGCACCTTCGGCCGCTACTGCGAGGGCTCCGAGGAT
  GCCTGTGAGGAGCCGTGCTTCCCGAGTGTCCACTGCGTTCCTGGGAAGGGCTGCGAGGCC
  TGCCCTCCAAACCTGACTGGGGATGGGCGGCACTGTGCGGCTCTGGGGAGCTCTTTCCTG
  TGTCAGAACCAGTCCTGCCCTGTGAATTACTGCTACAATCAAGGCCACTGCTACATCTCC
  CAGACTCTGGGCTGTCAGCCCATGTGCACCTGCCCCCCAGCCTTCACTGACAGCCGCTGC
  TTCCTGGCTGGGAACAACTTCAGTCCAACTGTCAACCTAGAACTTCCCTTAAGAGTCATC
  CAGCTCTTGCTCAGTGAAGAGGAAAATGCCTCCATGGCAGAAGTCAACGCCTCGGTGGCA
  TACAGACTGGGGACCCTGGACATGCGGGCCTTTCTCCGCAACAGCCAAGTGGAACGAATC
  GATTCTGCAGCACCGGCCTCGGGAAGCCCCATCCAACACTGGATGGTCATCTCGGAGTTC
  CAGTACCGCCCTCGGGGCCCGGTCATTGACTTCCTGAACAACCAGCTGCTGGCCGCGGTG
  GTGGAGGCGTTCTTATACCACGTTCCACGGAGGAGTGAGGAGCCCAGGAACGACGTGGTC
  TTCCAGCCCATCTCCGGGGAAGACGTGCGCGATGTGACAGCCCTGAACGTGAGCACGCTG
  AAGGCTTACTTCAGATGCGATGGCTACAAGGGCTACGACCTGGTCTACAGCCCCCAGAGC
  GGCTTCACCTGCGTGTCCCCGTGCAGTAGGGGCTACTGTGACCATGGAGGCCAGTGCCAG
  CACCTGCCCAGTGGGCCCCGCTGCAGCTGTGTGTCCTTCTCCATCTACACGGCCTGGGGC
  GAGCACTGTGAGCACCTGAGCATGAAACTCGACGCGTTCTTCGGCATCTTCTTTGGGGCC
  CTGGGCGGCCTCTTGCTGCTGGGGGTCGGGACGTTCGTGGTCCTGCGCTTCTGGGGTTGC
  TCCGGGGCCAGGTTCTCCTATTTCCTGAACTCAGCTGAGGCCTTGCCTTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_004532
• ORF Size: 3531 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_004532.2, NP_004523.2
• RefSeq Size: 4411
• RefSeq ORF: 3531
• Locus ID: 4585
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (4), also called MUC4/Y, lacks coding exon 2 as compared to transcript variant 1. As a result, variant 4 encodes isoform d, which has the same N- and C-termini as isoform a encoded by variant 1. Isoform d, thought to be a membrane-bound protein, lacks the variable length, highly glycosylated region found in isoform a.