Tpit (TBX19) (NM_005149) Human Untagged Clone

CAT#: SC303592

TBX19 (untagged)-Human T-box 19 (TBX19)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TBX19
• Synonyms: dJ747L4.1; TBS19; TPIT
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005149, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCATGAGTGAGCTGGGCACTCGGAAGCCCAGCGATGGCACTGTTTCTCATCTGCTCAATGTGGTGG
  AGAGTGAGCTTCAGGCAGGGAGGGAAAAAGGCGACCCTACGGAGAAGCAACTTCAGATCATCCTGGAGGA
  TGCACCTCTCTGGCAGAGATTCAAGGAAGTCACTAATGAGATGATTGTGACCAAGAATGGCAGACGGATG
  TTTCCAGTCCTAAAGATTAGTGTCACAGGGTTGGACCCCAATGCCATGTACTCCCTCCTGCTGGACTTTG
  TCCCTACGGACAGTCACCGCTGGAAGTACGTCAACGGGGAATGGGTGCCCGCTGGCAAGCCAGAGGTCTC
  CAGCCACAGCTGCGTCTACATTCACCCGGACTCCCCCAACTTTGGGGCCCACTGGATGAAAGCTCCCATC
  TCCTTCAGCAAAGTGAAGCTGACCAACAAGCTCAATGGAGGCGGGCAGATAATGTTGAATTCTCTGCATA
  AATATGAACCCCAGGTTCACATAGTGCGTGTTGGAAGTGCCCATCGAATGGTAACAAACTGCTCCTTCCC
  TGAAACCCAGTTCATAGCCGTGACTGCCTATCAGAATGAGGAGATAACGGCTCTCAAAATCAAGTACAAT
  CCTTTTGCCAAAGCCTTCTTGGATGCCAAGGAAAGAAATCACCTAAGAGACGTACCGGAGGCTATCTCTG
  AGAGCCAGCATGTGACCTATTCTCACTTGGGAGGCTGGATCTTTTCCAATCCAGATGGAGTGTGCACAGC
  AGGAAACTCCAATTACCAGTATGCCGCTCCTCTGCCTCTGCCTGCTCCCCACACCCACCATGGCTGTGAG
  CACTATTCGGGTCTCCGAGGACACCGGCAGGCTCCCTACCCTTCTGCGTACATGCACAGAAACCATTCTC
  CCTCAGTGAATTTGATAGAAAGCTCAAGCAATAATCTGCAAGTTTTCTCGGGACCTGACAGCTGGACTTC
  CTTATCCTCCACACCCCATGCCAGCATCCTGTCTGTACCCCACACCAACGGACCAATCAATCCAGGGCCC
  AGCCCCTACCCGTGCCTGTGGACCATCAGCAATGGTGCCGGAGGCCCCAGTGGGCCAGGCCCGGAGGTGC
  ACGCCAGCACCCCAGGAGCATTTCTCCTCGGAAACCCAGCTGTGACTTCACCCCCTTCTGTGCTCTCCAC
  CCAAGCACCCACTTCGGCTGGTGTGGAGGTTCTGGGGGAGCCCTCGCTAACCAGCATTGCTGTGTCCACC
  TGGACAGCAGTGGCCTCGCATCCCTTCGCGGGCTGGGGTGGCCCAGGAGCGGGTGGGCACCATTCTCCTT
  CCTCACTGGATGGTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_005149
• ORF Size: 1347 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005149.2, NP_005140.1
• RefSeq Size: 2882
• RefSeq ORF: 1347
• Locus ID: 9095
• Gene Summary: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. [provided by RefSeq, Jul 2008]