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Lipoprotein a (LPA) (NM_005577) Human Untagged Clone
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Other products for "LPA"
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Symbol | LPA |
| Synonyms | AK38; APOA; LP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_005577 edited
ATGGAACATAAGGAAGTGGTTCTTCTACTTCTTTTATTTCTGAAATCAGCAGCACCTGAG CAAAGCCATGTGGTCCAGGATTGCTACCATGGTGATGGACAGAGTTATCGAGGCACGTAC TCCACCACTGTCACAGGAAGGACCTGCCAAGCTTGGTCATCTATGACACCACATCAACAT AATAGGACCACAGAAAACTACCCAAATGCTGGCTTGATCATGAACTACTGCAGGAATCCA GATGCTGTGGCAGCTCCTTATTGTTATACGAGGGATCCCGGTGTCAGGTGGGAGTACTGC AACCTGACGCAATGCTCAGACGCAGAAGGGACTGCCGTCGCGCCTCCGACTGTTACCCCG GTTCCAAGCCTAGAGGCTCCTTCCGAACAAGCACCGACTGAGCAAAGGCCTGGGGTGCAG GAGTGCTACCATGGTAATGGACAGAGTTATCGAGGCACATACTCCACCACTGTCACAGGA AGAACCTGCCAAGCTTGGTCATCTATGACACCACACTCGCATAGTCGGACCCCAGAATAC TACCCAAATGCTGGCTTGATCATGAACTACTGCAGGAATCCAGATGCTGTGGCAGCTCCT TATTGTTATACGAGGGATCCCGGTGTCAGGTGGGAGTACTGCAACCTGACGCAATGCTCA GACGCAGAAGGGACTGCCGTCGCGCCTCCGACTGTTACCCCGGTTCCAAGCCTAGAGGCT CCTTCCGAACAAGCACCGACTGAGCAAAGGCCTGGGGTGCAGGAGTGCTACCATGGTAAT GGACAGAGTTATCGAGGCACATACTCCACCACTGTCACAGGAAGAACCTGCCAAGCTTGG TCATCTATGACACCACACTCGCATAGTCGGACCCCAGAATACTACCCAAATGCTGGCTTG ATCATGAACTACTGCAGGAATCCAGATGCTGTGGCAGCTCCTTATTGTTATACGAGGGAT CCCGGTGTCAGGTGGGAGTACTGCAACCTGACGCAATGCTCAGACGCAGAAGGGACTGCC GTCGCGCCTCCGACTGTTACCCCGGTTCCAAGCCTAGAGGCTCCTTCCGAACAAGCACCG ACTGAGCAGAGGCCTGGGGTGCAGGAGTGCTACCACGGTAATGGACAGAGTTATCGAGGC ACATACTCCACCACTGTCACTGGAAGAACCTGCCAAGCTTGGTCATCTATGACACCACAC TCGCATAGTCGGACCCCAGAATACTACCCAAATGCTGGCTTGATCATGAACTACTGCAGG AATCCAGATGCTGTGGCAGCTCCTTATTGTTATACGAGGGATCCCGGTGTCAGGTGGGAG TACTGCAACCTGACGCAATGCTCAGACGCAGAAGGGACTGCCGTCGCGCCTCCGACTGTT ACCCCGGTTCCAAGCCTAGAGGCTCCTTCCGAACAAGCACCGACTGAGCAAAGGCCTGGG GTGCAGGAGTGCTACCATGGTAATGGACAGAGTTATCGAGGCACATACTCCACCACTGTC ACAGGAAGAACCTGCCAAGCTTGGTCATCTATGACACCACACTCGCATAGTCGGACCCCA GAATACTACCCAAATGCTGGCTTGATCATGAACTACTGCAGGAATCCAGATGCTGTGGCA GCTCCTTATTGTTATACGAGGGATCCCGGTGTCAGGTGGGAGTACTGCAACCTGACGCAA TGCTCAGACGCAGAAGGGACTGCCGTCGCGCCTCCGACTGTTACCCCGGTTCCAAGCCTA GAGGCTCCTTCCGAACAAGCACCGACTGAGCAAAGGCCTGGGGTGCAGGAGTGCTACCAT GGTAATGGACAGAGTTATCGAGGCACATACTCCACCACTGTCACAGGAAGAACCTGCCAA GCTTGGTCATCTATGACACCACACTCGCATAGTCGGACCCCAGAATACTACCCAAATGCT GGCTTGATCATGAACTACTGCAGGAATCCAGATGCTGTGGCAGCTCCTTATTGTTATACG AGGGATCCCGGTGTCAGGTGGGAGTACTGCAACCTGACGCAATGCTCAGACGCAGAAGGG ACTGCCGTCGCGCCTCCGACTGTTACCCCGGTTCCAAGCCTAGAGGCTCCTTCCGAACAA GCACCGACTGAGCAAAGGCCTGGGGTGCAGGAGTGCTACCATGGTAATGGACAGAGTTAT CGAGGCACATACTCCACCACTGTCACAGGAAGAACCTGCCAAGCTTGGTCATCTATGACA CCACACTCGCATAGTCGGACCCCAGAATACTACCCAAATGCTGGCTTGATCATGAACTAC TGCAGGAATCCAGATGCTGTGGCAGCTCCTTATTGTTATACGAGGGATCCCGGTGTCAGG TGGGAGTACTGCAACCTGACGCAATGCTCAGACGCAGAAGGGACTGCCGTCGCGCCTCCG ACTGTTACCCCGGTTCCAAGCCTAGAGGCTCCTTCCGAACAAGCACCGACTGAGCAGAGG CCTGGGGTGCAGGAGTGCTACCACGGTAATGGACAGAGTTATCGAGGCACATACTCCACC ACTGTCACTGGAAGAACCTGCCAAGCTTGGTCATCTATGACACCACACTCGCATAGTCGG ACCCCAGAATACTACCCAAATGCTGGCTTGATCATGAACTACTGCAGGAATCCAGATCCT GTGGCAGCCCCTTATTGTTATACGAGGGATCCCAGTGTCAGGTGGGAGTACTGCAACCTG ACACAATGCTCAGACGCAGAAGGGACTGCCGTCGCGCCTCCAACTATTACCCCGATTCCA AGCCTAGAGGCTCCTTCTGAACAAGCACCAACTGAGCAAAGGCCTGGGGTGCAGGAGTGC TACCACGGAAATGGACAGAGTTATCAAGGCACATACTTCATTACTGTCACAGGAAGAACC TGCCAAGCTTGGTCATCTATGACACCACACTCGCATAGTCGGACCCCAGCATACTACCCA AATGCTGGCTTGATCAAGAACTACTGCCGAAATCCAGATCCTGTGGCAGCCCCTTGGTGT TATACAACAGATCCCAGTGTCAGGTGGGAGTACTGCAACCTGACACGATGCTCAGATGCA GAATGGACTGCCTTCGTCCCTCCGAATGTTATTCTGGCTCCAAGCCTAGAGGCTTTTTTT GAACAAGCACTGACTGAGGAAACCCCCGGGGTACAGGACTGCTACTACCATTATGGACAG AGTTACCGAGGCACATACTCCACCACTGTCACAGGAAGAACTTGCCAAGCTTGGTCATCT ATGACACCACACCAGCATAGTCGGACCCCAGAAAACTACCCAAATGCTGGCCTGACCAGG AACTACTGCAGGAATCCAGATGCTGAGATTCGCCCTTGGTGTTACACCATGGATCCCAGT GTCAGGTGGGAGTACTGCAACCTGACACAATGCCTGGTGACAGAATCAAGTGTCCTTGCA ACTCTCACGGTGGTCCCAGATCCAAGCACAGAGGCTTCTTCTGAAGAAGCACCAACGGAG CAAAGCCCCGGGGTCCAGGATTGCTACCATGGTGATGGACAGAGTTATCGAGGCTCATTC TCTACCACTGTCACAGGAAGGACATGTCAGTCTTGGTCCTCTATGACACCACACTGGCAT CAGAGGACAACAGAATATTATCCAAATGGTGGCCTGACCAGGAACTACTGCAGGAATCCA GATGCTGAGATTAGTCCTTGGTGTTATACCATGGATCCCAATGTCAGATGGGAGTACTGC AACCTGACACAATGTCCAGTGACAGAATCAAGTGTCCTTGCGACGTCCACGGCTGTTTCT GAACAAGCACCAACGGAGCAAAGCCCCACAGTCCAGGACTGCTACCATGGTGATGGACAG AGTTATCGAGGCTCATTCTCCACCACTGTTACAGGAAGGACATGTCAGTCTTGGTCCTCT ATGACACCACACTGGCATCAGAGAACCACAGAATACTACCCAAATGGTGGCCTGACCAGG AACTACTGCAGGAATCCAGATGCTGAGATTCGCCCTTGGTGTTATACCATGGATCCCAGT GTCAGATGGGAGTACTGCAACCTGACGCAATGTCCAGTGATGGAATCAACTCTCCTCACA ACTCCCACGGTGGTCCCAGTTCCAAGCACAGAGCTTCCTTCTGAAGAAGCACCAACTGAA AACAGCACTGGGGTCCAGGACTGCTACCGAGGTGATGGACAGAGTTATCGAGGCACACTC TCCACCACTATCACAGGAAGAACATGTCAGTCTTGGTCGTCTATGACACCACATTGGCAT CGGAGGATCCCATTATACTATCCAAATGCTGGCCTGACCAGGAACTACTGCAGGAATCCA GATGCTGAGATTCGCCCTTGGTGTTACACCATGGATCCCAGTGTCAGGTGGGAGTACTGC AACCTGACACGATGTCCAGTGACAGAATCGAGTGTCCTCACAACTCCCACAGTGGCCCCG GTTCCAAGCACAGAGGCTCCTTCTGAACAAGCACCACCTGAGAAAAGCCCTGTGGTCCAG GATTGCTACCATGGTGATGGACGGAGTTATCGAGGCATATCCTCCACCACTGTCACAGGA AGGACCTGTCAATCTTGGTCATCTATGATACCACACTGGCATCAGAGGACCCCAGAAAAC TACCCAAATGCTGGCCTGACCGAGAACTACTGCAGGAATCCAGATTCTGGGAAACAACCC TGGTGTTACACAACCGATCCGTGTGTGAGGTGGGAGTACTGCAATCTGACACAATGCTCA GAAACAGAATCAGGTGTCCTAGAGACTCCCACTGTTGTTCCAGTTCCAAGCATGGAGGCT CATTCTGAAGCAGCACCAACTGAGCAAACCCCTGTGGTCCGGCAGTGCTACCATGGTAAT GGCCAGAGTTATCGAGGCACATTCTCCACCACTGTCACAGGAAGGACATGTCAATCTTGG TCATCCATGACACCACACCGGCATCAGAGGACCCCAGAAAACTACCCAAATGATGGCCTG ACAATGAACTACTGCAGGAATCCAGATGCCGATACAGGCCCTTGGTGTTTTACCATGGAC CCCAGCATCAGGTGGGAGTACTGCAACCTGACGCGATGCTCAGACACAGAAGGGACTGTG GTCGCTCCTCCGACTGTCATCCAGGTTCCAAGCCTAGGGCCTCCTTCTGAACAAGACTGT ATGTTTGGGAATGGGAAAGGATACCGGGGCAAGAAGGCAACCACTGTTACTGGGACGCCA TGCCAGGAATGGGCTGCCCAGGAGCCCCATAGACACAGCACGTTCATTCCAGGGACAAAT AAATGGGCAGGTCTGGAAAAAAATTACTGCCGTAACCCTGATGGTGACATCAATGGTCCC TGGTGCTACACAATGAATCCAAGAAAACTTTTTGACTACTGTGATATCCCTCTCTGTGCA TCCTCTTCATTTGATTGTGGGAAGCCTCAAGTGGAGCCGAAGAAATGTCCTGGAAGCATT GTAGGGGGGTGTGTGGCCCACCCACATTCCTGGCCCTGGCAAGTCAGTCTCAGAACAAGG TTTGGAAAGCACTTCTGTGGAGGCACCTTAATATCCCCAGAGTGGGTGCTGACTGCTGCT CACTGCTTGAAGAAGTCCTCAAGGCCTTCATCCTACAAGGTCATCCTGGGTGCACACCAA GAAGTGAACCTCGAATCTCATGTTCAGGAAATAGAAGTGTCTAGGCTGTTCTTGGAGCCC ACACAAGCAGATATTGCCTTGCTAAAGCTAAGCAGGCCTGCCGTCATCACTGACAAAGTA ATGCCAGCTTGTCTGCCATCCCCAGACTACATGGTCACCGCCAGGACTGAATGTTACATC ACTGGCTGGGGAGAAACCCAAGGTACCTTTGGGACTGGCCTTCTCAAGGAAGCCCAGCTC CTTGTTATTGAGAATGAAGTGTGCAATCACTATAAGTATATTTGTGCTGAGCATTTGGCC AGAGGCACTGACAGTTGCCAGGGTGACAGTGGAGGGCCTCTGGTTTGCTTCGAGAAGGAC AAATACATTTTACAAGGAGTCACTTCTTGGGGTCTTGGCTGTGCACGCCCCAATAAGCCT GGTGTCTATGCTCGTGTTTCAAGGTTTGTTACTTGGATTGAGGGAATGATGAGAAATAAT TAA |
| Restriction Sites | Please inquire |
| ACCN | NM_005577 |
| Insert Size | 6500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005577.1, NP_005568.1 |
| RefSeq Size | 13938 bp |
| RefSeq ORF | 6489 bp |
| Locus ID | 4018 |
| Cytogenetics | 6q25.3-q26 |
| Protein Families | Druggable Genome |
| Gene Summary | 'The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence. [provided by RefSeq, Dec 2009]' |
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