Meprin beta (MEP1B) (NM_005925) Human Untagged Clone

CAT#: SC303704

MEP1B (untagged)-Human meprin A, beta (MEP1B)


  "NM_005925" in other vectors (5)

Reconstitution Protocol

USD 760.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol MEP1B
Synonyms endopeptidase-2; meprin A, beta; N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta subunit; PABA peptide hydrolase; PPH beta
Vector pCMV6-XL6
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_005925 edited
GGTACCCAACTGGAAGCTACAACATGGATTTATGGAATCTGTCTTGGTTTCTGTTCTTGG
ATGCTCTTCTCGTGATTTCTGGCTTGGCAACTCCAGAAAACTTTGATGTAGATGGCGGAA
TGGACCAGGACATATTTGATATCAATGAAGGTTTGGGACTGGATCTTTTTGAAGGTGACA
TCAGACTTGATAGGGCACAAATTAGAAATTCCATCATTGGAGAAAAGTATAGATGGCCTC
ATACCATTCCATATGTTCTAGAAGATAGCTTGGAAATGAATGCTAAGGGAGTTATCCTCA
ATGCATTTGAACGTTATCGCCTTAAAACATGTATTGACTTTAAGCCTTGGGCTGGAGAAA
CAAACTATATATCAGTGTTCAAGGGCAGTGGCTGCTGGTCTTCAGTAGGAAATAGGCGGG
TTGGGAAGCAAGAACTTTCCATCGGGGCAAACTGTGACCGAATAGCAACAGTTCAACACG
AGTTCCTCCACGCTCTGGGATTCTGGCATGAGCAGTCGCGTTCTGACCGGGATGACTATG
TCAGGATAATGTGGGACAGAATTCTGTCAGGCAGAGAGCACAATTTTAACACCTATAGTG
ACGATATATCAGATTCCCTGAATGTTCCCTATGATTACACTTCAGTAATGCACTACAGTA
AAACTGCATTCCAAAATGGAACAGAGCCGACAATTGTCACAAGAATCTCAGACTTTGAGG
ATGTGATCGGCCAACGAATGGATTTCAGTGACTCTGATCTCCTAAAGTTGAATCAACTGT
ATAACTGCTCCTCTTCCTTGAGTTTTATGGACTCGTGCAGTTTTGAACTGGAAAATGTGT
GTGGCATGATCCAAAGTTCAGGAGATAATGCTGACTGGCAACGGGTTTCACAGGTTCCCA
GGGGGCCAGAGAGTGATCACTCCAACATGGGCCAGTGCCAAGGTTCTGGTTTCTTCATGC
ATTTCGATAGCAGCTCTGTAAATGTGGGGGCCACAGCAGTGCTGGAAAGTAGAACGCTGT
ACCCTAAAAGAGGATTTCAGTGCCTGCAATTTTACTTATATAACAGTGGCAGTGAAAGTG
ATCAACTGAACATCTATATCAGGGAGTATTCTGCAGACAATGTGGATGGCAATTTAACCC
TTGTGGAAGAAATAAAAGAAATACCCACTGGGAGCTGGCAACTTTATCATGTAACATTGA
AAGTGACCAAGAAGTTTAGAGTGGTGTTTGAAGGACGCAAAGGCTCTGGTGCATCACTGG
GTGGTCTGTCTATTGATGACATCAATCTTTCGGAAACACGGTGCCCTCATCATATCTGGC
ATATAAGGAATTTCACACAGTTCATTGGCAGCCCAAATGGAACTCTGTATAGCCCTCCAT
TTTACTCTTCTAAAGGTTATGCCTTTCAGATTTACTTAAATCTAGCCCATGTGACTAATG
CAGGGATATATTTCCACTTGATCTCTGGAGCCAATGATGATCAATTACAGTGGCCATGTC
CTTGGCAACAAGCCACAATGACACTTTTGGATCAAAATCCTGACATTCGACAGCGTATGT
CCAATCAGCGGAGTATAACTACAGACCCATTTATGACCACCGATAATGGAAACTATTTCT
GGGACAGGCCTTCCAAAGTGGGAACAGTGGCTTTGTTCCCTAATGGAACTCAGTTTAGAA
GAGGTGGGGGCTATGGAACCAGTGCCTTTATAACCCACGAAAGGCTGAAAAGCAGAGATT
TTATAAAAGGAGATGATGTTTATATCCTACTGACAGTGGAAGACATATCTCACCTCAACT
CTACACAAATCCAGCTAACACCAGCCCCTAGTGTTCAAGACCTCTGCTCAAAAACCACCT
GTAAAAATGACGGTGTCTGCACTGTTCGAGATGGCAAAGCTGAGTGCAGGTGCCAGTCAG
GGGAAGACTGGTGGTACATGGGAGAAAGGTGTGAAAAGAGAGGCTCCACCCGAGACACCA
TAGTCATTGCTGTTTCATCTACTGTTGCTGTGTTTGCCTTGATGCTGATCATCACCCTTG
TCAGTGTCTATTGCACCAGGAAGAAATATCGTGAAAGGATGAGCTCAAATCGACCAAATT
TGACTCCGCAAAATCAGCATGCTTTTTGAAGATTAACTCGACAATATGGCCAGCTAATGA
AATTAAAAAGGATTCTTCATCATGGATTTCGCCTAAGTGAAAGCTT
Restriction Sites Please inquire     
ACCN NM_005925
Insert Size 2300 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_005925.1, NP_005916.1
RefSeq Size 2326 bp
RefSeq ORF 2103 bp
Locus ID 4225
Cytogenetics 18q12.1
Protein Families Druggable Genome, Transmembrane
Gene Summary 'Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine. [provided by RefSeq, Oct 2011]'
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

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