PROP1 (NM_006261) Human Untagged Clone

CAT#: SC303762

PROP1 (untagged)-Human PROP paired-like homeobox 1 (PROP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PROP1
• Synonyms: CPHD2; PROP-1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006261, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAAGCAGAAAGGAGGCGCCAGGCTGAGAAGCCAAAGAAGGGGCGAGTCGGCAGCAGCCTGTTGCCTG
  AGAGACACCCGGCCACTGGGACCCCGACCACCACGGTGGACTCGAGTGCTCCACCCTGCAGAAGGCTCCC
  TGGTGCAGGAGGGGGGAGATCAAGGTTCTCCCCGCAAGGAGGACAGAGGGGCCGCCCGCACTCCCGGCGC
  CGCCACCGCACCACCTTCAGCCCAGTGCAGTTGGAACAGCTGGAGTCAGCCTTTGGGAGGAACCAGTACC
  CCGACATCTGGGCCCGAGAGAGTCTTGCCCGGGACACTGGCCTCAGTGAGGCCCGAATCCAGGTCTGGTT
  CCAGAACCGCAGAGCTAAGCAACGGAAGCAAGAGCGCTCACTGCTTCAGCCTCTGGCCCATCTGTCTCCT
  GCCGCCTTTTCCAGCTTCTTGCCAGAGTCCACTGCTTGCCCCTATTCTTACGCAGCACCACCACCACCAG
  TGACCTGCTTCCCTCACCCCTACAGCCATGCCCTCCCTTCCCAGCCCTCCACAGGAGGCGCCTTTGCTTT
  GTCACACCAGTCTGAGGACTGGTACCCTACCTTGCACCCAGCCCCTGCCGGCCATCTGCCCTGCCCCCCA
  CCCCCTCCCATGCTCCCCCTCAGCCTTGAGCCATCCAAGTCCTGGAACTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_006261
• ORF Size: 681 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006261.4, NP_006252.3
• RefSeq Size: 1464
• RefSeq ORF: 681
• Locus ID: 5626
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone. [provided by RefSeq, Sep 2011]