DKK1 (NM_012242) Human Untagged Clone

CAT#: SC303946

DKK1 (untagged)-Human dickkopf homolog 1 (Xenopus laevis) (DKK1)


  "NM_012242" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol DKK1
Synonyms DKK-1; SK
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_012242 edited
CCCTGCAGTCAGGACTCTGGGACCGCAGGGGGCTCCCGGACCCTGACTCTGCAGCCGAAC
CGGCACGGTTTCGTGGGGACCCAGGCTTGCAAAGTGACGGTCATTTTCTCTTTCTTTCTC
CCTCTTGAGTCCTTCTGAGATGATGGCTCTGGGCGCAGCGGGAGCTACCCGGGTCTTTGT
CGCGATGGTAGCGGCGGCTCTCGGCGGCCACCCTCTGCTGGGAGTGAGCGCCACCTTGAA
CTCGGTTCTCAATTCCAACGCTATCAAGAACCTGCCCCCACCGCTGGGCGGCGCTGCGGG
GCACCCAGGCTCTGCAGTCAGCGCCGCGCCGGGAATCCTGTACCCGGGCGGGAATAAGTA
CCAGACCATTGACAACTACCAGCCGTACCCGTGCGCAGAGGACGAGGAGTGCGGCACTGA
TGAGTACTGCGCTAGTCCCACCCGCGGAGGGGACGCAGGCGTGCAAATCTGTCTCGCCTG
CAGGAAGCGCCGAAAACGCTGCATGCGTCACGCTATGTGCTGCCCCGGGAATTACTGCAA
AAATGGAATATGTGTGTCTTCTGATCAAAATCATTTCCGAGGAGAAATTGAGGAAACCAT
CACTGAAAGCTTTGGTAATGATCATAGCACCTTGGATGGGTATTCCAGAAGAACCACCTT
GTCTTCAAAAATGTATCACACCAAAGGACAAGAAGGTTCTGTTTGTCTCCGGTCATCAGA
CTGTGCCTCAGGATTGTGTTGTGCTAGACACTTCTGGTCCAAGATCTGTAAACCTGTCCT
GAAAGAAGGTCAAGTGTGTACCAAGCATAGGAGAAAAGGCTCTCATGGACTAGAAATATT
CCAGCGTTGTTACTGTGGAGAAGGTCTGTCTTGCCGGATACAGAAAGATCACCATCAAGC
CAGTAATTCTTCTAGGCTTCACACTTGTCAGAGACACTAAACCAGCTATCCAAATGCAGT
GAACTCCTTTTATATAATAGATGCTATGAAAACCTTTTATGACCTTCATCAACTCAATCC
TAAGGATATACAAGTTCTGTGGTTTCAGTTAAGCATTCCAATAACACCTTCCAAAAAAAA
AAAAAAAAAAAAAA
>OriGene 5' read for NM_012242 unedited
NAAGTCAACAATTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCCCTGCA
GTCAGGACTCTGGGACCGCAGGGGCTCCCGGACCCTGACTCTGCAGCCGAACCGGCACGG
TTTCGTGGGGACCCAGGCTTGCAAAGTGACGGTCATTTTCTCTTTCTTTCTCCCTCTTGA
GTCCTTCTGAGATGATGGCTCTGGGCGCAGCGGGAGCTACCCGGGTCTTTGTCGCGATGG
TAGCGGCGGCTCTCGGCGGCCACCCTCTGCTGGGAGTGAGCGCCACCTTGAACTCGGTTC
TCAATTCCAACGCTATCAAGAACCTGCCCCCACCGCTGGGCGGCGCTGCGGGGCACCCAG
GCTCTGCAGTCAGCGCCGCGCCGGGAATCCTGTACCCGGGCGGGAATAAGTACCAGACCA
TTGACAACTACCAGCCGTACCCGTGCGCAGAGGACGAGGAGTGCGGCACTGATGAGTACT
GCGCTAGTCCCACCCGCGGAGGGGACGCATGCGTGCAAATCTGTCTCGCCTGCAGGAAGC
GCCGAANACGCTGCATGCGTCACGCTATGTGCTGCCCCGGGAATTACTGCAAAAATGGAA
TATGTGTGTCTTCTGATCAAAATCATTTCCGAGGAGAAATTGANGAAACCATCACTGANA
GCTTTGGTAATGATCATAGCACCTTGGATGGGTATTCCAGAAGAACCACCTTGTCTTCAA
AAATGTATCACACCANAGGACAAGAAGGTTCTGTTTGTCTCCGGTCATCAGACTGTGCCT
CAAGATTGTGTTGTGCTAGACACTTCTGGGTCAAGATCTGNTAACCTGTCCTGAAAGAAG
GTCAAGTGTGTACCAAGCATAGGAGGAAAGGCTCTCATGGACTAGAAATATTCCAGCGTT
GNTACTGTGG
>OriGene 3' read for NM_012242 unedited
NACTTGTATATCCTTAGGATTGAGTTGATGAAGGTCATAAAAGGTTTTCATAGCATCTAT
TATATAAAAGGAGTTCACTGCATTTGGATAGCTGGTTTAGTGTCTCTGACAAGTGTGAAG
CCTAGAAGAATTACTGGCTTGATGGTGATCTTTCTGTATCCGGCAAGACAGACCTTCTCC
ACAGTAACAACGCTGGAATATTTCTAGTCCATGAGAGCCTTTTCTCCTATGCTTGGTACA
CACTTGACCTTCTTTCAGGACAGGTTTACAGATCTTGGACCAGAAGTGTCTAGCACAACA
CAATCCTGAGGCACAGTCTGATGACCGGAGACAAACAGAACCTTCTTGTCCTTTGGTGTG
ATACATTTTTGAAGACAAGGTGGTTCTTCTGGAATACCCATCCAAGGTGCTATGATCATT
ACCAAAGCTTTCAGTGATGGTTTCCTCAATTTCTCCTCGGAAATGATTTTGATCAGAAGA
CACACATATTCCATTTTTGCAGTAATTCCCGGGGCAGCACATAGCGTGACGCATGCAGCG
TTTTCGGCGCTTCCTGCAGGCGAGACAGATTTGCACGCCTGCGTCCCCTCCGCGGGTGGG
ACTAGCGCAGTACTCATCAGTGCCGCACTCCTCGTCCTCTGCGCACGGGTACGGCTGGTA
GTTGTCAATGGTCTGGTACTTATTCCCGCCCGGGTACAGGATTCCCGGCGCGGCGCTGAC
TGCAGAGCCTGGGTGCCCCGCAGCGCCGCCCCAGCGTGGGGGCAGGTTCTTGATAGCGTT
GGAATTGAGAACCGAGTTCAAGGTGGCGCTCACTCCCAGCAGAGGGTGGCCGCCGAGAGC
CGCCGCTACCATCGCGACAAAACCCGGGTAGCTCCCGCTGCGCCCAGAACATCA
Restriction Sites Please inquire     
ACCN NM_012242
ORF Size 801 bp
Insert Size 1103
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
Reference Data
RefSeq NM_012242.2, NP_036374.1
RefSeq Size 1815
RefSeq ORF 801
Locus ID 22943
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway
Protein Pathways Wnt signaling pathway
Gene Summary This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017]

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