BMP10 (NM_014482) Human Untagged Clone

CAT#: SC304116

BMP10 (untagged)-Human bone morphogenetic protein 10 (BMP10)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BMP10
• Synonyms: MGC126783
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_014482 edited
  ATGGGCTCTCTGGTCCTGACACTGTGCGCTCTTTTCTGCCTGGCAGCTTACTTGGTTTCT
  GGCAGCCCCATCATGAACCTAGAGCAGTCTCCTCTGGAAGAAGATATGTCCCTCTTTGGT
  GATGTTTTCTCAGAGCAAGACGGTGTCGACTTTAACACACTGCTCCAGAGCATGAAGGAT
  GAGTTTCTTAAGACACTAAACCTCTCTGACATCCCCACGCAGGATTCAGCCAAGGTGGAC
  CCACCAGAGTACATGTTGGAACTCTACAACAAATTTGCAACAGATCGGACCTCCATGCCC
  TCTGCCAACATCATTAGGAGTTTCAAGAATGAAGATCTGTTTTCCCAGCCGGTCAGTTTT
  AATGGGCTCCGAAAATACCCCCTCCTCTTCAATGTGTCCATTCCTCACCATGAAGAGGTC
  ATCATGACTGAACTTAGGCTATACACACTGGTGCAAAGGGATCGTATGATATACGATGGA
  GTAGACCGGAAAATTACCATTTTTGAAGTGCTGGAGAGCAAAGGGGATAATGAGGGAGAA
  AGAAACATGCTGGTCTTGGTGTCTGGGGAGATATATGGAACCAACAGTGAGTGGGAGACT
  TTTGATGTCACAGATGCCATCAGACGTTGGCAAAAGTCAGGCTCATCCACCCACCAGCTG
  GAGGTCCACATTGAGAGCAAACACGATGAAGCTGAGGATGCCAGCAGTGGACGGCTAGAA
  ATAGATACCAGTGCCCAGAATAAGCATAACCCTTTGCTCATCGTGTTTTCTGATGACCAA
  AGCAGTGACAAGGAGAGGAAGGAGGAACTGAATGAAATGATTTCCCATGAGCAACTTCCA
  GAGCTGGACAACTTGGGCCTGGATAGCTTTTCCAGTGGACCTGGGGAAGAGGCTTTGTTG
  CAGATGAGATCAAACATCATCTATGACTCCACTGCCCGAATCAGAAGGAACGCCAAAGGA
  AACTACTGTAAGAGGACCCCGCTCTACATCGACTTCAAGGAGATTGGGTGGGACTCCTGG
  ATCATCGCTCCGCCTGGATACGAAGCCTATGAATGCCGTGGTGTTTGTAACTACCCCCTG
  GCAGAGCATCTCACACCCACAAAGCATGCAATTATCCAGGCCTTGGTCCACCTCAAGAAT
  TCCCAGAAAGCTTCCAAAGCCTGCTGTGTGCCCACAAAGCTAGAGCCCATCTCCATCCTC
  TATTTAGACAAAGGCGTCGTCACCTACAAGTTTAAATACGAAGGCATGGCCGTCTCCGAA
  TGTGGCTGTAGATAG
  
• Restriction Sites: Please inquire
• ACCN: NM_014482
• ORF Size: 1275 bp
• Insert Size: 1500
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: There is one SNP in ORF.

Reference Data

• RefSeq: NM_014482.1, NP_055297.1
• RefSeq Size: 1584
• RefSeq ORF: 1275
• Locus ID: 27302
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. [provided by RefSeq, Aug 2016]