TRPM5 (NM_014555) Human Untagged Clone

CAT#: SC304125

TRPM5 (untagged)-Human transient receptor potential cation channel, subfamily M, member 5 (TRPM5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRPM5
• Synonyms: LTRPC5; MTR1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC304125 sequence for NM_014555 edited (data generated by NextGen Sequencing)
  
  
  ATGCAGGATGTCCAAGGCCCCCGTCCCGGAAGCCCCGGGGATGCTGAAGACCGGCGGGAGCTGGGCTTGC
  ACAGGGGCGAGGTCAACTTTGGAGGGTCTGGGAAGAAGCGAGGCAAGTTTGTACGGGTGCCGAGCGGAGT
  GGCCCCGTCTGTGCTCTTTGACCTGCTGCTTGCTGAGTGGCACCTGCCAGCCCCCAACCTGGTGGTGTCC
  CTGGTGGGTGAGGAGCAGCCTTTCGCCATGAAGTCCTGGCTGCGGGATGTGCTGCGCAAGGGGCTGGTGA
  AGGCGGCTCAGAGCACAGGAGCCTGGATCCTGACCAGTGCCCTCCGCGTGGGCCTGGCCAGGCATGTCGG
  GCAGGCCGTGCGCGACCACTCGCTGGCCAGCACGTCCACCAAGGTCCGTGTGGTTGCTGTCGGCATGGCC
  TCGCTGGGCCGCGTCCTGCACCGCCGCATTCTGGAGGAGGCCCAGGAGGATTTTCCTGTCCACTACCCTG
  AGGATGACGGCGGCAGCCAGGGCCCCCTCTGTTCACTGGACAGCAACCTCTCCCACTTCATCCTGGTGGA
  GCCAGGCCCCCCGGGGAAGGGCGATGGGCTGACGGAGCTGCGGCTGAGGCTGGAGAAGCACATCTCGGAG
  CAGAGGGCGGGCTACGGGGGCACTGGCAGCATCGAGATCCCTGTCCTCTGCTTGCTGGTCAATGGTGATC
  CCAACACCTTGGAGAGGATCTCCAGGGCCGTGGAGCAGGCTGCCCCGTGGCTGATCCTGGCAGGCTCGGG
  GGGCATCGCCGATGTGCTTGCTGCCCTAGTGAACCAGCCCCACCTCCTGGTGCCCAAGGTGGCCGAGAAG
  CAGTTTAAGGAGAAGTTCCCCAGCAAGCATTTCTCTTGGGAGGACATCGTGCGCTGGACCAAGCTGCTGC
  AGAACATCACCTCACACCAGCACCTGCTCACCGTGTATGACTTCGAGCAGGAGGGCTCCGAGGAGCTGGA
  CACGGTCATCCTGAAGGCGCTGGTGAAAGCCTGCAAGAGCCACAGCCAGGAGCCTCAGGACTATCTGGAT
  GAGCTCAAGCTGGCCGTGGCCTGGGACCGCGTGGACATCGCCAAGAGTGAGATCTTCAATGGGGACGTGG
  AGTGGAAGTCCTGTGACCTGGAGGAGGTGATGGTGGACGCCCTGGTCAGCAACAAGCCCGAGTTTGTGCG
  CCTCTTTGTGGACAACGGCGCAGACGTGGCCGACTTCCTGACGTATGGGCGGCTGCAGGAGCTCTACCGC
  TCTGTGTCACGCAAGAGCCTGCTCTTCGACCTGCTGCAGCGGAAGCAGGAGGAGGCCCGGCTGACGCTGG
  CCGGCCTGGGCACCCAGCAGGCCCGGGAGCCACCCGCGGGGCCACCGGCCTTCTCCCTGCACGAGGTCTC
  CCGCGTACTCAAGGACTTCCTGCAGGACGCCTGCCGAGGCTTCTACCAGGACGGCCGGCCAGGGGACCGC
  AGGAGGGCGGAGAAGGGCCCGGCCAAGCGGCCCACGGGCCAGAAGTGGCTGCTGGACCTGAACCAGAAGA
  GCGAGAACCCCTGGCGGGACCTGTTCCTGTGGGCCGTGCTGCAGAACCGCCACGAGATGGCCACCTACTT
  CTGGGCCATGGGCCAGGAAGGTGTGGCAGCCGCACTGGCCGCCTGCAAAATCCTCAAAGAGATGTCGCAC
  CTGGAGACGGAGGCCGAGGCGGCCCGAGCCACGCGCGAGGCGAAATACGAGCGGCTGGCCCTTGACCTCT
  TCTCCGAGTGCTACAGCAACAGTGAGGCCCGCGCCTTCGCCCTGCTGGTGCGCCGGAACCGCTGCTGGAG
  CAAGACCACCTGCCTGCACCTGGCCACCGAGGCTGACGCCAAGGCCTTCTTTGCCCACGACGGCGTTCAG
  GCCTTCCTGACCAGGATCTGGTGGGGGGACATGGCCGCAGGCACGCCCATCCTGCGGCTGCTAGGAGCCT
  TCCTCTGCCCCGCCCTCGTCTATACCAACCTCATCACCTTCAGTGAGGAAGCTCCCCTGAGGACAGGCCT
  GGAGGACCTGCAGGACCTGGACAGCCTGGACACGGAGAAGAGCCCGCTGTATGGCCTGCAGAGCCGGGTG
  GAGGAGCTGGTGGAGGCGCCGAGGGCTCAGGGTGACCGAGGCCCACGTGCTGTCTTCCTGCTCACACGCT
  GGCGGAAATTCTGGGGCGCTCCCGTGACTGTGTTCCTGGGGAACGTGGTCATGTACTTCGCCTTCCTCTT
  CCTGTTCACCTACGTCCTGCTGGTGGACTTCAGGCCGCCCCCCCAGGGCCCCTCAGGGCCCGAGGTCACC
  CTCTACTTCTGGGTCTTTACGCTGGTGCTGGAGGAAATCCGGCAGGGCTTCTTCACAGACGAGGACACAC
  ACCTGGTGAAGAAGTTCACACTGTATGTGGGGGACAACTGGAACAAGTGTGACATGGTGGCCATCTTCCT
  GTTCATCGTGGGTGTCACCTGCAGGATGCTGCCGTCGGCGTTTGAGGCTGGCCGCACAGTCCTCGCCATG
  GACTTCATGGTGTTCACGCTGCGGCTGATCCATATCTTTGCCATACACAAGCAGCTGGGCCCCAAGATCA
  TCGTGGTAGAGCGCATGATGAAGGACGTCTTCTTCTTCCTCTTCTTTCTGAGCGTGTGGCTCGTGGCCTA
  CGGTGTCACCACCCAGGCGCTGCTGCACCCCCATGACGGCCGCCTGGAGTGGATCTTCCGCCGGGTGCTC
  TACCGGCCCTACCTGCAGATCTTCGGCCAGATCCCACTGGACGAGATTGATGAAGCCCGTGTGAACTGCT
  CCACCCACCCACTGCTGCTGGAGGACTCACCATCCTGCCCCAGCCTCTATGCCAACTGGCTGGTCATCCT
  CCTGCTGGTCACCTTCCTGTTGGTCACCAATGTGCTGCTCATGAACCTGCTCATCGCCATGTTCAGCTAC
  ACGTTCCAGGTGGTGCAGGGCAACGCAGACATGTTCTGGAAGTTCCAGCGCTACAACCTGATTGTGGAGT
  ACCACGAGCGCCCCGCCCTGGCCCCGCCCTTCATCCTGCTCAGCCACCTGAGCCTGACGCTCCGCCGGGT
  CTTCAAGAAGGAGGCTGAGCACAAGCGGGAGCACCTGGAGAGAGACCTGCCAGACCCCCTGGACCAGAAG
  GTCGTCACCTGGGAGACAGTCCAGAAGGAGAACTTCCTGAGCAAGATGGAGAAGCGGAGGAGGGACAGCG
  AGGGGGAGGTGCTGCGGAAAACCGCCCACAGAGTGGACTTCATTGCCAAGTACCTCGGGGGTCTGAGAGA
  GCAAGAAAAGCGCATCAAGTGTCTGGAGTCACAGATCAACTACTGCTCGGTGCTCGTGTCCTCCGTGGCT
  GACGTGCTGGCCCAGGGTGGCGGCCCCCGGAGCTCTCAGCACTGTGGCGAGGGAAGCCAGCTGGTGGCTG
  CTGACCACAGAGGTGGTTTAGATGGCTGGGAACAACCCGGGGCTGGCCAGCCTCCCTCGGACACCTGA
  
  Clone variation with respect to NM_014555.3
  189:a=>g 761:c=>t 1263:t=>c
• Restriction Sites: Please inquire
• ACCN: NM_014555
• ORF Size: 3498 bp
• Insert Size: 3500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a good match to NM_014555.2 except one SNP.

Reference Data

• RefSeq: NM_014555.2, NP_055370.1
• RefSeq Size: 3946
• RefSeq ORF: 3498
• Locus ID: 29850
• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
• Protein Pathways: Taste transduction
• Gene Summary: This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele. [provided by RefSeq, Oct 2010]