SLC39A14 (NM_015359) Human Untagged Clone

CAT#: SC304299

SLC39A14 (untagged)-Human solute carrier family 39 (zinc transporter), member 14 (SLC39A14), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC39A14
• Synonyms: cig19; HCIN; HMNDYT2; LZT-Hs4; NET34; ZIP14
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015359, the custom clone sequence may differ by one or more nucleotides
  ATGAAGCTGCTGCTGCTGCACCCGGCCTTCCAGAGCTGCCTCCTGCTGACCCTGCTTGGC
  TTATGGAGAACCACCCCTGAGGCTCACGCTTCATCCCTGGGTGCACCAGCTATCAGCGCT
  GCCTCCTTCCTGCAGGATCTAATACATCGGTATGGCGAGGGTGACAGCCTCACTCTGCAG
  CAGCTGAAGGCCCTACTCAACCACCTGGATGTGGGAGTGGGCCGGGGTAATGTCACCCAG
  CACGTGCAAGGACACAGGAACCTCTCCACGTGCTTTAGTTCTGGAGACCTCTTCACTGCC
  CACAATTTCAGCGAGCAGTCGCGGATTGGGAGCAGCGAGCTCCAGGAGTTCTGCCCCACC
  ATCCTCCAGCAGCTGGATTCCCGGGCCTGCACCTCGGAGAACCAGGAAAACGAGGAGAAT
  GAGCAGACGGAGGAGGGGCGGCCAAGCGCTGTTGAAGTGTGGGGCTTTGGTTTTCTCAGT
  GTCTCACTGATTAACCTGGCCTCTCTCCTGGGAGTCCTCGTCCTGCCCTGCACAGAGAAA
  GCGTTTTTCAGCCGTGTGCTCACTTACTTCATCGCCCTGTCCATTGGAACGCTGCTGTCT
  AACGCGCTATTCCAGCTCATCCCAGAGGCATTTGGTTTCAACCCTCTGGAAGATTATTAT
  GTCTCCAAGTCTGCAGTGGTGTTTGGGGGCTTTTATCTTTTCTTTTTCACAGAGAAGATC
  TTGAAGATTCTTCTTAAGCAGAAAAATGAGCATCATCATGGACACAGCCATTATGCCTCT
  GAGTCGCTTCCCTCCAAGAAGGACCAGGAGGAGGGGGTGATGGAGAAGCTGCAGAACGGG
  GACCTGGACCACATGATTCCTCAGCACTGCAGCAGTGAGCTGGACGGCAAGGCGCCCATG
  GTGGACGAGAAGGTCATTGTGGGCTCGCTCTCTGTGCAGGACCTGCAGGCTTCCCAGAGT
  GCTTGCTACTGGCTGAAAGGTGTCCGCTACTCTGATATCGGCACTCTGGCCTGGATGATC
  ACTCTGAGCGACGGCCTCCATAATTTCATCGATGGCCTGGCCATCGGTGCTTCCTTCACT
  GTGTCAGTTTTCCAAGGCATCAGCACCTCGGTGGCCATCCTCTGTGAGGAGTTCCCACAT
  GAGCTAGGAGACTTTGTCATCCTGCTCAACGCTGGGATGAGCATCCAACAAGCTCTCTTC
  TTCAACTTCCTTTCTGCCTGCTGCTGCTACCTGGGTCTGGCCTTTGGCATCCTGGCCGGC
  AGCCACTTCTCTGCCAACTGGATTTTTGCGCTAGCTGGAGGAATGTTCTTGTATATTTCT
  CTGGCTGATATGTTCCCTGAGATGAATGAGGTCTGTCAAGAGGATGAAAGGAAGGGCAGC
  ATCTTGATTCCATTTATCATCCAGAACCTGGGCCTCCTGACTGGATTCACCATCATGGTG
  GTCCTCACCATGTATTCAGGACAGATCCAGATTGGGTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_015359
• ORF Size: 1479 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015359.1, NP_056174.1
• RefSeq Size: 4627
• RefSeq ORF: 1479
• Locus ID: 23516
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia. [provided by RefSeq, May 2017]
  Transcript Variant: This variant (2) contains an alternate in-frame coding exon compared to variant 1, resulting in an isoform (b) of the same length, however, with several aa differences in the mid region compared to isoform a.