MAVS (NM_020746) Human Untagged Clone

CAT#: SC304815

MAVS (untagged)-Human mitochondrial antiviral signaling protein (MAVS), nuclear gene encoding mitochondrial protein, transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAVS
• Synonyms: CARDIF; IPS-1; IPS1; VISA
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_020746 edited
  ATGCCGTTTGCTGAAGACAAGACCTATAAGTATATCTGCCGCAATTTCAGCAATTTTTGC
  AATGTGGATGTTGTAGAGATTCTGCCTTACCTGCCCTGCCTCACAGCAAGAGACCAGGAT
  CGACTGCGGGCCACCTGCACACTCTCAGGGAACCGGGACACCCTCTGGCATCTCTTCAAT
  ACCCTTCAGCGGCGGCCCGGCTGGGTGGAGTACTTCATTGCGGCACTGAGGGGCTGTGAG
  CTAGTTGATCTCGCGGACGAAGTGGCCTCTGTCTACCAGAGCTACCAGCCTCGGACCTCG
  GACCGTCCCCCAGACCCACTGGAGCCACCGTCACTTCCTGCTGAGAGGCCAGGGCCCCCC
  ACACCTGCTGCGGCCCACAGCATCCCCTACAACAGCTGCAGAGAGAAGGAGCCAAGTTAC
  CCCATGCCTGTCCAGGAGACCCAGGCGCCAGAGTCCCCAGGAGAGAATTCAGAGCAAGCC
  CTGCAGACGCTCAGCCCCAGAGCCATCCCAAGGAATCCAGATGGTGGCCCCCTGGAGTCC
  TCCTCTGACCTGGCAGCCCTCAGCCCTCTGACCTCCAGCGGGCATCAGGAGCAGGACACA
  GAACTGGGCAGTACCCACACAGCAGGTGCGACCTCCAGCCTCACACCATCCCGTGGGCCT
  GTGTCTCCATCTGTCTCCTTCCAGCCCCTGGCCCGTTCCACCCCCAGGGCAAGCCGCTTG
  CCTGGACCCACAGGGTCAGTTGTATCTACTGGCACCTCCTTCTCCTCCTCATCCCCTGGC
  TTGGCCTCTGCAGGGGCTGCAGAGGGTAAACAGGGTGCAGAGAGTGACCAGGCCGAGCCT
  ATCATCTGCTCCAGTGGGGCAGAGGCACCTGCCAACTCTCTGCCCTCCAAAGTGCCTACC
  ACCTTGATGCCTGTGAACACAGTGGCCCTGAAAGTGCCTGCCAACCCAGCATCTGTCAGC
  ACAGTGCCCTCCAAGTTGCCAACTAGCTCAAAGCCCCCTGGTGCAGTGCCTTCTAATGCG
  CTCACCAATCCAGCACCATCCAAATTGCCCATCAACTCAACCCGTGCTGGCATGGTGCCA
  TCCAAAGTGCCTACTAGCATGGTGCTCACCAAGGTGTCTGCCAGCACAGTCCCCACTGAC
  GGGAGCAGCAGAAATGAGGAGACCCCAGCAGCTCCAACACCCGCCGGCGCCACTGGAGGC
  AGCTCAGCCTGGCTAGACAGCAGCTCTGAGAATAGGGGCCTTGGGTCGGAGCTGAGTAAG
  CCTGGCGTGCTGGCATCCCAGGTAGACAGCCCGTTCTCGGGCTGCTTCGAGGATCTTGCC
  ATCAGTGCCAGCACCTCCTTGGGCATGGGGCCCTGCCATGGCCCAGAGGAGAATGAGTAT
  AAGTCCGAGGGCACCTTTGGGATCCACGTGGCTGAGAACCCCAGCATCCAGCTCCTGGAG
  GGCAACCCTGGGCCACCTGCGGACCCGGATGGCGGCCCCAGGCCACAAGCCGACCGGAAG
  TTCCAGGAGAGGGAGGTGCCATGCCACAGGCCCTCACCTGGGGCTCTGTGGCTCCAGGTG
  GCTGTGACAGGGGTGCTGGTAGTCACACTCCTGGTGGTGCTGTACCGGCGGCGTCTGCAC
  TAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for XM_045472 unedited
  NTTATTTCCCCCGCCCGTTGCCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATAT
  AAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGC
  CGCGAATTCGGCACGAGGCTGGGCCCCGGGCGGCGGTCGCCAGGTCTCAGGGCCGGGGGT
  ACCCGAGTCTCGTTTCCTCTCAGTCCATCCACCCTTCATGGGGCCAGAGCCCTCTCTCCA
  GAATCTGAGCAGCAATGCCGTTTGCTGAAGACAAGACCTATAAGTATATCTGCCGCAATT
  TCAGCAATTTTTGCAATGTGGATGTTGTAGAGATTCTGCCTTACCTGCCCTGCCTCACAG
  CAAGAGACCAGGATCGACTGCGGGCCACCTGCACACTCTCAGGGAACCGGGACACCCTCT
  GGCATCTCTTCAATACCCTTCAGCGGCGGCCCGGCTGGGTGGAGTACTTCATTGCGGCAC
  TGAGGGGCTGTGAGCTAGTTGATCTCGCGGACGAAGTGGCCTCTGTCTACCAGAGCTACC
  AGCCTCGGACCTCGGACCGTCCCCCAGACCCACTGGAGCCACCGTCACTTCCTGCTGAGA
  GGCCAGGGCCCCCCACACCTGCTGCGGCCCACAGCATCCCCTACAACAGCTGCAGAGAGA
  AGGAGCCAAGTTACCCCATGCCTGTCCAGGAGACCCAGGCGCCAGAGTCCCCAGGAGAAG
  ATTCAGAGCAAGCCCTGCAGACGCTCAGCCCCAGAGCCATCCCAGGAATCCAGATGGTGG
  CCCCCTGGAGTCCTCCTCTGACCTGGCAGCCCTCAGCCCTCTGACCTCCAGCGGGCATCA
  AGAGCAGGACCCAGACTGGGCAGTACCCACACAGGAGGTGCGACCTCCAGCCTACACATT
  CCGNGGGGCCTGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for XM_045472 unedited
  GNGATCNAGTTTTTTTTTTTTTTTTTTGTAGAGACGGGGTTTCACCCTGTTGGCCAGGCT
  GGTCTTGAACTCCAGACCTCAGGCGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATT
  ACAGGCGTGAGCCACTGCGCTCGGCCCATGTTGCCTTTTTGAGATACTTTTTTCAAAGCT
  ACCCTGGAACGGTAATACAATAAAACTAGTACCTGTGCATAAATTGTTAACTGACCTGCC
  CAGCATGGGTACCTAACTGGGGTTTAAGGTAGGGGGACAGAGGGCTTTTTAAGATTGGTG
  GTGGGGGATGGGGATTAATACAGACCGCTCGGGTAGGGTCCACTCCTGGTTCCAGGGGGC
  AGGTTGCTGGACTTGGAGCATGGGATGAACAAATGTTCATAAATTGAGATCATTAAGTTG
  CTGAACTTCCCTACGGCATAGGAGTGAAAAAAATGTTTCACCCACGGGAAGGCGTATAAC
  CCCGTTAGTCGACAGCTTGGGGTGCGGCTCAATGGTTGCCCCCCCCCGGGGGGCTTGTAT
  CCTTGGCCCTTTCACAATCCCCAATGCGGGGGGGGCCCCGCGCACTCGCCCTTTACTGGA
  CACCCCCTCAACAAATCTTCCTGACTACCCCCCCCCCGCCACTCCGATTTGATCCTCGGT
  GTATTTTGGCCACAATCCCCCCTTCCTGGTATGTGGTATTTCTGAGTGGAGGGAAAACAA
  AACTCCTTTGGGGCGGACAAACCGCCCTTACTCTTCTCACACCCTATACATCTTCCCTCC
  CTCGTGTTTCACTCCTCCTTTCTCTTTCATATTTCTCTAATTTCCTTTCAATAATATATA
  CGGGTTGGGTGCCCCACGAACACATGCCGCGGTA
  
• Restriction Sites: Please inquire
• ACCN: NM_020746
• ORF Size: 1623 bp
• Insert Size: 4100
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_020746.2, NP_065797.2
• RefSeq Size: 2936
• RefSeq ORF: 1623
• Locus ID: 57506
• Protein Families: Transmembrane
• Protein Pathways: Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway
• Gene Summary: This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.