ZBTB4 (NM_020899) Human Untagged Clone

CAT#: SC304861

ZBTB4 (untagged)-Human zinc finger and BTB domain containing 4 (ZBTB4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZBTB4
• Synonyms: KAISO-L1; ZNF903
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_020899, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCCCCCCCTGCAGAGGTGACGGACCCGTCCCATGCCCCCGCCGTCCTGCGCCAGCTCAATGAACAGC
  GGCTCCGTGGCCTCTTCTGTGACGTCACCCTCATAGCCGGAGACACCAAGTTCCCTGCTCACCGCAGCGT
  CCTGGCTGCTTCAAGTCCCTTCTTCAGAGAGGCCCTGCTCACTTCAGCCCCACTACCCCTTCCACCAGCT
  ACTGGGGGCGCCGCACCCAACCCTGCCACCACCACAGCTGCCTCTTCCTCCTCCTCCTCTTCCTCGTCTT
  CTTCCTCTTCTTCCTCCTCTGCTTCTTCTTCTTCTTCCTCTTCCTCTTCCTCTCCCCCTCCAGCCTCTCC
  CCCTGCTTCTTCCCCACCCCGGGTCCTGGAGTTGCCAGGAGTCCCAGCAGCTGCGTTTTCTGATGTCCTC
  AACTTCATCTACAGCGCCCGGCTCGCACTGCCTGGTGGTGGAGGGGACGGGGCAGCTGTAGCAGAGATTG
  GAGCTTTGGGGCGCCGTCTGGGCATCTCCCGCCTTCAGGGCCTGGGGGAGGGAGGTGATGCCTGGGTACC
  TCCTACCCCAGCCCCCATGGCCACCTCGCAGCCTGAAGAGGACAGCTTTGGGCCCGGGCCCAGGCCAGCT
  GGGGAGTGGGAGGGTGACAGGGCTGAGGCCCAGGCCCCTGACTTGCAGTGCTCCCTGCCCCGGCGGCCCC
  TCCCCTGCCCCCAGTGTGGAAAAAGCTTCATCCATCCCAAACGGCTGCAGACCCATGAGGCCCAGTGCCG
  ACGAGGGGCCAGCACGCGGGGGTCTACAGGGCTGGGAGCTGGGGGCGCTGGCCCTGGTGGTCCTGCAGGG
  GTGGACGCCTCAGCCCTGCCTCCACCAGTGGGCTTCCGAGGGGGCCCCGAGCACGTGGTGAAGGTGGTGG
  GCGGCCACGTGCTGTATGTGTGCGCGGCCTGCGAGCGTTCCTACGTGACCCTGTCCAGTCTGAAGAGACA
  CAGCAATGTACACTCGTGGCGGAGGAAGTACCCCTGCCGCTATTGTGAGAAAGTGTTTGCTCTGGCGGAG
  TACCGCACGAAGCATGAAGTGTGGCACACGGGGGAGCGCAGGTACCAGTGCATCTTCTGTTGGGAGACCT
  TTGTCACTTACTATAACCTGAAGACCCACCAGCGAGCCTTCCACGGCATTAGCCCGGGCCTCCTTGCCAG
  TGAGAAGACACCCAATGGAGGCTACAAGCCCAAGCTCAATACACTCAAGCTCTACCGCCTGCTCCCCATG
  CGGGCAGCCAAGCGGCCCTACAAGACCTACAGCCAGGGAGCCCCGGAGGCTCCCCTTTCTCCAACCCTCA
  ACACACCGGCCCCTGTGGCAATGCCAGCCAGCCCGCCGCCTGGGCCTCCACCTGCCCCAGAGCCTGGCCC
  TCCACCCTCTGTCATCACTTTTGCCCACCCAGCCCCCTCTGTCATTGTCCATGGGGGCAGTAGCAGTGGT
  GGAGGGGGGAGTGGGACGGCCAGCACAGGAGGGTCCCAAGCTGCCTCGGTTATCACTTACACTGCTCCCC
  CGAGGCCACCCAAGAAACGAGAATACCCACCTCCTCCCCCTGAGCCTGCAGCCACACCCACCAGCCCAGC
  CACAGCAGTCAGCCCAGCCACCGCTGCAGGGCCAGCCATGGCCACCACCACGGAGGAGGCCAAGGGCCGG
  AATCCACGGGCTGGAAGGACTCTGACTTACACAGCCAAGCCAGTGGGCGGGATTGGTGGAGGTGGGGGTC
  CCCCCACAGGGGCTGGCCGGGGCCCCTCTCAGCTGCAGGCTCCACCTCCACTGTGTCAGATCACTGTGCG
  AATAGGGGAGGAGGCCATCGTCAAGCGCCGCATCTCAGAGACTGACCTGCGTCCTGGGGAGCTGAGCGGA
  GAGGAGATGGAGGAGAGTGAGGAGGACGAAGAGGAGGAGGACGAAGAGGAGGAGGAGGAGGATGAGGAGG
  AATCAAAGGCTGGTGGGGAGGACCAGCTCTGGAGGCCCTACTACTCCTACAAGCCTAAGCGCAAGGCTGG
  AGCTGCTGGAGGTGCCAGTGTGGGGGGCAGTGGGCTGCCCCGAGGCCGCCGGCCACCACGTTGGAGGCAG
  AAGCTGGAACGGAGGAGCTGGGAGGAAACCCCAGCGGCCGAGAGCCCAGCGGGACGTGCCCGCACAGAGC
  GGAGGCACCGATGCGGGGACTGTGCCCAGACCTTCACCACCCTGAGAAAGCTGCGGAAGCACCAAGAGGC
  CCACGGTGGGGGCTCCCACAGCTCCCGGGCCGGACGGAGGCCCTCCACCCGCTTTACCTGCCCCCACTGC
  GCCAAGGTGTGCAAGACCGCAGCTGCCCTGAGCCGCCACGGGCAGAGGCATGCTGCTGAGCGGCCCGGGG
  GCACCCCAACCCCTGTCATTGCCTATTCCAAGGGCAGCGCTGGCACCAGGCCCGGGGATGTCAAGGAGGA
  AGCCCCCCAAGAGATGCAAGTCTCCTCATCCAGCGGTGAGGCAGGTGGCGGGAGCACTGCTGCTGAGGAA
  GCTTCCGAGACCGCCTCACTCCAGGACCCTATCATTTCAGGGGGTGAGGAGCCCCCAGTAGTGGCAAGCG
  GGGGCAGCTATGTATACCCACCTGTGCAGGAATTTCCACTGGCCTTGATTGGGGGCGGCCGGGAACCTGG
  CGGTGGCAGGGGAAAATCTGGGAGTGAAGGGCCAGTGGGGGCTGGTGAGGGGGACCGGATGGAGGGGATA
  GGGGCTGCCAAAGTCACTTTCTACCCTGAGCCCTACCCGCTCGTCTATGGCCCCCAGCTCCTTGCCGCCT
  ACCCTTACAACTTCAGTAACTTGGCCGCTCTCCCGGTTGCTCTCAACATGGTCCTACCTGATGAGAAGGG
  TGCGGGGGCCCTTCCCTTCCTACCAGGGGTCTTTGGCTACGCAGTGAATCCTCAAGCAGCACCCCCTGCC
  CCACCAACACCACCTCCCCCAACTCTTCCTCCACCAATTCCCCCTAAGGGAGAAGGGGAAAGGGCAGGGG
  TTGAGAGAACCCAGAAGGGCGATGTGGGGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_020899
• ORF Size: 3042 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_020899.3, NP_065950.2
• RefSeq Size: 5961
• RefSeq ORF: 3042
• Locus ID: 57659
• Gene Summary: Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) and variant 2 encode the same protein.