CRLF2 (NM_022148) Human Untagged Clone

CAT#: SC305006

CRLF2 (untagged)-Human cytokine receptor-like factor 2 (CRLF2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CRLF2
• Synonyms: CRL2; CRLF2Y; TSLPR
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_022148 edited
  ATGGGGCGGCTGGTTCTGCTGTGGGGAGCTGCCGTCTTTCTGCTGGGAGGCTGGATGGCT
  TTGGGGCAAGGAGGAGCAGAAGGAGTACAGATTCAGATCATCTACTTCAATTTAGAAACC
  GTGCAGGTGACATGGAATGCCAGCAAATACTCCAGGACCAACCTGACTTTCCACTACAGA
  TTCAACGGTGATGAGGCCTATGACCAGTGCACCAACTACCTTCTCCAGGAAGGTCACACT
  TCGGGGTGCCTCCTAGACGCAGAGCAGCGAGACGACATTCTCTATTTCTCCATCAGGAAT
  GGGACGCACCCCGTTTTCACCGCAAGTCGCTGGATGGTTTATTACCTGAAACCCAGTTCC
  CCGAAGCACGTGAGATTTTCGTGGCATCAGGATGCAGTGACGGTGACGTGTTCTGACCTG
  TCCTACGGGGATCTCCTCTATGAGGTTCAGTACCGGAGCCCCTTCGACACCGAGTGGCAG
  TCCAAACAGGAAAATACCTGCAACGTCACCATAGAAGGCTTGGATGCCGAGAAGTGTTAC
  TCTTTCTGGGTCAGGGTGAAGGCTATGGAGGATGTATATGGGCCAGACACATACCCAAGC
  GACTGGTCAGAGGTGACATGCTGGCAGAGAGGCGAGATTCGGGATGCCTGTGCAGAGACA
  CCAACGCCTCCCAAACCAAAGCTGTCCAAATTTATTTTAATTTCCAGCCTGGCCATCCTT
  CTGATGGTGTCTCTCCTCCTTCTGTCTTTATGGAAATTATGGAGAGTGAGGAAGTTTCTC
  ATTCCCAGCGTGCCAGACCCGAAATCCATCTTCCCCGGGCTCTTTGAGATACACCAAGGG
  AACTTCCAGGAGTGGATCACAGACACCCAGAACGTGGCCCACCTCCACAAGATGGCAGGT
  GCAGAGCAAGAAAGTGGCCCCGAGGAGCCCCTGGTAGTCCAGTTGGCCAAGACTGAAGCC
  GAGTCTCCCAGGATGCTGGACCCACAGACCGAGGAGAAAGAGGCCTCTGGGGGATCCCTC
  CAGCTTCCCCACCAGCCCCTCCAAGGCGGTGATGTGGTCACAATCGGGGGCTTCACCTTT
  GTGATGAATGACCGCTCCTACGTGGCGTTGTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022148 unedited
  GGGCAATCGTAATACGACTCCTATAGGGCGGCGCGAGAAAAAACCCTTATGGGGCGGCTG
  GTTCTGCTGGGGGGAGCTGCCGTCTTTCTGCTGGGAGGCTGGATGGCTTTGGGGCAAGGA
  GGAGCAGAAGGAGTACAGATTCAGATCATCTACTTCAATTTAGAAACCGTGCAGGTGACA
  TGGAATGCCAGCAAATACTCCAGGACCAACCTGACTTTCCACTACAGATTCAACGGTGAT
  GAGGCCTATGACCAGTGCACCAACTACCTTCTCCAGGAAGGTCACACTTCGGGGTGCCTC
  CTAGACGCAGAGCAGCGAGACGACATTCTCTATTTCTCCATCAGGAATGGGACGCACCCC
  GTTTTCACCGCAAGTCGCTGGATGGTTTATTACCTGAAACCCAGTTCCCCGAAGCACGTG
  AGATTTTCGTGGCATCAGGATGCAGTGACGGTGACGTGTTCTGACCTGTCCTACGGGGAT
  CTCCTCTATGAGGTTCAGTACCGGAGCCCCTTCGACACCGAGTGGCAGTCCAAACAGGAA
  AATACCTGCAACGTCACCATAGAAGGCTTGGATGCCGAGAAGTGTTACTCTTTCTGGGTC
  AGGGTGAAGGCTATGGAGGATGTATATGGGCCAGACACATACCCCAAGCGACTGGTCAGA
  GGTGACATGCTGGCAGAGAGGCGAGGATTCGGGATGCCTGTGCAGAGACACCAACGCCCT
  CCCAAACCAAAAGCTGTCCAAATTTATTTTAATTTCCCAGCCTGGCCATCCTTCTGATGG
  TGTCTCTCCTCCTTCTGTCTTTATGGAAATTACGGAGAGTGAGGAAGTTTCTCATTCCCA
  GCGTGCACAGACCCGAATCCATCTTCCCCGGTCTCTTGGAAATACCACCAAGGGACACTT
  CCAGGAGTTGGATCCACAGACACCCCAAAAACGTTGGGCCACC
  
• Restriction Sites: Please inquire
• ACCN: NM_022148
• ORF Size: 1116 bp
• Insert Size: 1300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by two amino acids.

Reference Data

• RefSeq: NM_022148.2, NP_071431.2
• RefSeq Size: 1579
• RefSeq ORF: 1116
• Locus ID: 64109
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
  Transcript Variant: This variant (1) encodes the longer isoform (1).