GRHL2 (NM_024915) Human Untagged Clone

CAT#: SC305189

GRHL2 (untagged)-Human grainyhead-like 2 (Drosophila) (GRHL2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GRHL2
• Synonyms: BOM; DFNA28; ECTDS; PPCD4; TFCP2L3
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_024915 edited
  ATTGGATCAAACATGTCACAAGAGTCGGACAATAATAAAAGACTAGTGGCCTTAGTGCCC
  ATGCCCAGTGACCCTCCATTCAATACCCGAAGAGCCTACACCAGTGAGGATGAAGCCTGG
  AAGTCATACTTGGAGAATCCCCTGACAGCAGCCACCAAGGCCATGATGAGCATTAATGGT
  GATGAGGACAGTGCTGCTGCCCTCGGCCTGCTCTATGACTACTACAAGGTTCCTCGAGAC
  AAGAGGCTGCTGTCTGTAAGCAAAGCAAGTGACAGCCAAGAAGACCAGGAGAAAAGAAAC
  TGCCTTGGCACCAGTGAAGCCCAGAGTAATTTGAGTGGAGGAGAAAACCGAGTGCAAGTC
  CTAAAGACTGTTCCAGTGAACCTTTCCCTAAATCAAGATCACCTGGAGAATTCCAAGCGG
  GAACAGTACAGCATCAGCTTCCCCGAGAGCTCTGCCATCATCCCGGTGTCGGGAATCACG
  GTGGTGAAAGCTGAAGATTTCACACCAGTTTTCATGGCCCCACCTGTGCACTATCCCCGG
  GGAGATGGGGAAGAGCAACGAGTGGTTATCTTTGAACAGACTCAGTATGACGTGCCCTCG
  CTGGCCACCCACAGCGCCTATCTCAAAGACGACCAGCGCAGCACTCCGGACAGCACATAC
  AGCGAGAGCTTCAAGGACGCAGCCACAGAGAAATTTCGGAGTGCTTCAGTTGGGGCTGAG
  GAGTACATGTATGATCAGACATCAAGTGGCACATTTCAGTACACCCTGGAAGCCACCAAA
  TCTCTCCGTCAGAAGCAGGGGGAGGGCCCCATGACCTACCTCAACAAAGGACAGTTCTAT
  GCCATAACACTCAGCGAGACCGGAGACAACAAATGCTTCCGACACCCCATCAGCAAAGTC
  AGGAGTGTGGTGATGGTGGTCTTCAGTGAAGACAAAAACAGAGATGAACAGCTCAAATAC
  TGGAAATACTGGCACTCTCGGCAGCATACGGCGAAGCAGAGGGTCCTTGACATTGCCGAT
  TACAAGGAGAGCTTTAATACGATTGGAAACATTGAAGAGATTGCATATAATGCTGTTTCC
  TTTACCTGGGACGTGAATGAAGAGGCGAAGATTTTCATCACCGTGAATTGCTTGAGCACA
  GATTTCTCCTCCCAAAAAGGGGTGAAAGGACTTCCTTTGATGATTCAGATTGACACATAC
  AGTTATAACAATCGTAGCAATAAACCCATTCATAGAGCTTATTGCCAGATCAAGGTCTTC
  TGTGACAAAGGAGCAGAAAGAAAAATCCGAGATGAAGAGCGGAAGCAGAACAGGAAGAAA
  GGGAAAGGCCAGGCCTCCCAAACTCAATGCAACAGCTCCTCTGATGGGAAGTTGGCTGCC
  ATACCTTTACAGAAGAAGAGTGACATCACCTACTTCAAAACCATGCCTGATCTCCACTCA
  CAGCCAGTTCTCTTCATACCTGATGTTCACTTTGCAAACCTGCAGAGGACCGGACAGGTG
  TATTACAACACGGATGATGAACGAGAAGGTGGCAGTGTCCTTGTTAAACGGATGTTCCGG
  CCCATGGAAGAGGAGTTTGGTCCAGTGCCTTCAAAGCAGATGAAAGAAGAAGGGACAAAG
  CGAGTGCTCTTGTACGTGAGGAAGGAGACTGACGATGTGTTCGATGCATTGATGTTGAAG
  TCTCCCACAGTGAAGGGCCTGATGGAAGCGATATCTGAGAAATATGGGCTGCCCGTGGAG
  AAGATAGCAAAGCTTTACAAGAAAAGCAAAAAAGGCATCTTGGTGAACATGGATGACAAC
  ATCATCGAGCACTACTCGAACGAGGACACCTTCATCCTCAACATGGAGAGCATGGTGGAG
  GGCTTCAAGGTCACGCTCATGGAAATCTAGCCCTGGGTTTGGCATCCGCTTTGGCTGGAG
  CTCTCAGTGCGTTCCTCCCTGAGAGAGACAGAAGCCCCAGCCCCAGAACCTGGAGACCCA
  TCTCCCCCATCTCACAACTGCTGTTACAAGACCGTGCTGGGGAGTGGGGCAAGGGACAGG
  CCCCACTGTCGGTGTGCTTGGCCCATCCACTGGCACCTACCACGGAGCTGAAGCCTGAGC
  CCCTCAGGAAGGTGCCTTAGGCCTGTTGGATTCCTATTTATTGCCCACCTTTTCCTGGAG
  CCCAGGTCCAGGCCCGCCAGGACTCTGCAGGTCACTGCTAGCTCCAGATGAGACCGTCCA
  GCGTTCCCCCTTCAAGAGAAACACTCATCCCGAACAGCCTAAAAAATTCCCATCCCTTCT
  CTCTCACCCCTCCATATCTATCTCCCGAGTGGCTGGACAAAATGAGCTACGTCTGGGTGC
  AGTAGTTATAGGTGGGGCAAGAGGTGGATGCCCACTTTCTGGTCAGACACCTTTAGGTTG
  CTCTGGGGAAGGCTGTCTTGCTAAATACCTCCAGGGTTCCCAGCAAGTGGCCACCAGGCC
  TTGTACAGGAAGACATTCAGTCACCGTGTAATTAGTAACACAGAAAGTCTGCCTGTCTGC
  ATTGTACATAGTGTTTATAATATTGTAATAATATATTTTACCTGTGGTATGTGGGCATGT
  TTACTGCCACTGGCCTAGAGGAGACACAGACCTGGAGACCGTTTTAATGGGGGTTTTTGC
  CTCTGTGCCTGTTCAAGAGACTTGCAGGGCTAGGTAGAGGGCCTTTGGGATGTTAAGGTG
  ACTGCAGCTGATGCCAAGATGGACTCTGCAATGGGCATACCTGGGGGCTCGTTCCCTGTC
  CCCAGAGGAAGCCCCCTCTCCTTCTCCATGGGCATGACTCTCCTTCGAGGCCACCACGTT
  TATCTCACAATGATGTGTTTTGCTTGACTTTCCCTTTGCGCTGTCTCATGGGAAAGGTCA
  TTCTGTCTGAGACCCCAGCTCCTTCTCCAGCTTTGGCTGCGGGCATGGCCTGAGCTTTCT
  GGAGAGCCTCTGCAGGGGGTTTGCCATCAGGGCCCTGTGGCTGGGTCTGCTGCAGAGCTC
  CTTGGCTATCAGGAGAATCCTGGACACTGTACTGTGCCTCCCAGTTTACAAACACGCCCT
  TCATCTCAAGTGGCCCTTTAAAAGGCCTGCTGCCATGTGAGAGCTGTGAA
  
• Restriction Sites: Please inquire
• ACCN: NM_024915
• ORF Size: 1878 bp
• Insert Size: 3100
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_024915.1.

Reference Data

• RefSeq: NM_024915.1, NP_079191.1
• RefSeq Size: 4793
• RefSeq ORF: 1878
• Locus ID: 79977
• Protein Families: Transcription Factors
• Gene Summary: The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28). [provided by RefSeq, Mar 2009]