ARHGEF4 (NM_032995) Human Untagged Clone

CAT#: SC305530

ARHGEF4 (untagged)-Human Rho guanine nucleotide exchange factor (GEF) 4 (ARHGEF4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARHGEF4
• Synonyms: ASEF; ASEF1; GEF4; STM6
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_032995, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCCTGGGAAGAACCAGCAGGTGAGAAGCCCAGTTGCTCTCACAGTCAGAAGGCGTTCCACATGGAGC
  CTGCCCAGAAGCCCTGCTTCACCACTGACATGGTGACATGGGCCCTCCTCTGCATCTCTGCAGAGACTGT
  GCGTGGGGAGGCTCCTTCACAGCCTAGGGGCATCCCTCACCGCTCGCCCGTCAGTGTGGATGACCTGTGG
  CTGGAGAAGACACAGAGAAAGAAGTTGCAGAAGCAGGCCCACGTCGAAAGGAGGCTGCACATAGGGGCAG
  TGCACAAAGATGGAGTCAAGTGCTGGAGAAAGACGATCATTACCTCTCCAGAGTCTTTGAATCTCCCTAG
  AAGAAGCCATCCACTCTCCCAGAGTGCTCCAACGGGACTGAACCACATGGGCTGGCCAGAGCACACACCA
  GGCACTGCCATGCCTGATGGAGCTCTGGACACAGCTGTCTGCGCTGACGAAGTGGGGAGCGAGGAGGACC
  TGTATGATGACCTGCACAGCTCCAGCCACCACTACAGCCACCCTGGAGGGGGTGGGGAGCAGCTGGCTAT
  CAATGAGCTCATCAGCGATGGCAGTGTGGTCTGCGCTGAAGCACTCTGGGACCATGTCACCATGGACGAC
  CAGGAGCTGGGCTTCAAAGCTGGGGACGTCATCGAAGTGATGGATGCCACCAACAGAGAGTGGTGGTGGG
  GCCGGGTCGCCGATGGCGAGGGCTGGTTTCCAGCCAGCTTCGTTCGGCTGAGGGTGAATCAGGACGAGCC
  CGCGGATGACGACGCCCCTCTGGCCGGGAACAGCGGAGCGGAGGACGGCGGGGCGGAGGCGCAGAGCAGC
  AAGGACCAGATGCGGACCAACGTCATCAACGAGATCCTCAGCACTGAGCGGGACTACATCAAGCACCTGC
  GCGACATCTGCGAGGGCTACGTCCGGCAGTGCCGCAAGCGCGCAGACATGTTCAGCGAGGAGCAGCTGCG
  TACCATCTTCGGGAACATCGAGGACATCTACCGCTGCCAGAAGGCCTTCGTGAAGGCCCTGGAGCAGAGG
  TTCAACCGCGAGCGCCCACACCTGAGCGAGCTGGGTGCCTGCTTCCTGGAGCATCAAGCCGACTTCCAGA
  TCTACTCGGAGTACTGCAATAACCACCCCAACGCCTGCGTGGAGCTCTCCCGGCTCACCAAGCTCAGCAA
  GTACGTGTACTTCTTCGAGGCCTGCCGGCTGCTGCAGAAGATGATTGACATCTCCCTGGATGGCTTCCTG
  CTGACTCCGGTGCAGAAGATCTGCAAGTACCCTCTGCAGCTGGCCGAGCTGCTCAAATACACGCACCCCC
  AGCACAGGGACTTCAAGGATGTTGAAGCCGCCTTGCATGCCATGAAGAACGTGGCCCAGCTCATCAACGA
  GCGGAAGCGGAGACTTGAGAACATCGACAAGATTGCTCAGTGGCAGAGCTCCATAGAGGACTGGGAGGGA
  GAAGATCTCTTGGTCAGGAGCTCAGAACTCATCTACTCGGGGGAGCTGACTCGAGTTACACAGCCTCAAG
  CCAAAAGCCAGCAGCGAATGTTCTTTCTCTTTGACCACCAGCTCATCTACTGTAAGAAGGACCTGCTCCG
  CCGCGACGTGTTGTACTACAAGGGCCGGCTGGACATGGACGGCCTGGAGGTGGTGGACCTGGAGGACGGG
  AAGGACAGAGACCTCCATGTGAGCATCAAGAACGCCTTCCGGCTGCACCGTGGCGCCACAGGGGACAGCC
  ACCTGCTGTGCACCAGGAAGCCCGAGCAGAAGCAGCGCTGGCTCAAGGCCTTTGCCAGGGAGAGGGAGCA
  GGTGCAGCTGGACCAGGAGACAGGCTTCTCCATCACTGAACTGCAGAGGAAGCAGGCCATGCTGAATGCC
  AGCAAGCAGCAGGTCACAGGGAAGCCCAAAGGTAGGCGGACAGCAGCCCCACCTCCTCGGCTGCCCGGTC
  CTTACCCTGCTGACATCATTCCCTTCTCTGAACCACAAAGCCAAGCCAGCTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_032995
• ORF Size: 2013 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_032995.2, NP_127462.1
• RefSeq Size: 3860
• RefSeq ORF: 2013
• Locus ID: 50649
• Protein Families: Druggable Genome
• Protein Pathways: Regulation of actin cytoskeleton
• Gene Summary: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jun 2013]
  Transcript Variant: This variant (2) has an additional segment in the 3' region, compared to variant 1. This causes the reading frame shift, and the resulting isoform (b) is shorter and has a distinct C-terminus, compared to isoform a.