SPAG11B (NM_058201) Human Untagged Clone

CAT#: SC305769

SPAG11B (untagged)-Human sperm associated antigen 11B (SPAG11B), transcript variant D

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SPAG11B
• Synonyms: EDDM2B; EP2; EP2C; EP2D; HE2; HE2C; SPAG11; SPAG11A
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_058201, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGCAACGATTGCTCCCGTCCGTCACCAGCCTTCTCCTTGTGGCCCTGCTGTTTCCAGGATCGTCTC
  AAGCCAGACATGTGAACCACTCAGCCACTGAGGCTCTCGGAGAACTCAGGGAAAGAGCCCCTGGGCAAGG
  CACAAACGGGTTTCAGCTGCTACGCCACGCAGTGAAACGGGACCTCTTACCACCGCGCACCCCACCTTAC
  CAAGGGGATGTTCCACCGGGAATTAGAAATACCATCTGCCATATGCAGCAAGGGATCTGCAGACTTTTTT
  TCTGCCATTCTGGTGAGAAAAAGCGTGACATTTGCTCTGATCCCTGGAATAGGTGTTGCGTATCAAATAC
  AGATGAAGAAGGAAAAGAGAAACCAGAGATGGATGGCAGATCTGGGATCTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_058201
• ORF Size: 402 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_058201.2, NP_478108.2
• RefSeq Size: 718
• RefSeq ORF: 402
• Locus ID: 10407
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (D) is also called the beta1 transcript. It lacks three internal exons. The C-terminus of the encoded isoform (D) is identical to that of isoform E encoded by variant E. Isoform D has a region with similarity to beta-defensins.