WFDC8 (NM_130896) Human Untagged Clone

CAT#: SC305924

WFDC8 (untagged)-Human WAP four-disulfide core domain 8 (WFDC8), transcript variant a

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WFDC8
• Synonyms: C20orf170; dJ461P17.1; HEL-S-292; WAP8
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_130896, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTGGACTGTCCGAACTGAAGGAGGGCACTTTCCTCTCCATAGCCCCACCTTCTCCTGGAGGAATGTAG
  CTTTCCTGCTGCTTCTCTCCCTTGCTTTGGAGTGGACTTCTGCAATGCTGACCAAGAAGATCAAACACAA
  ACCAGGGTTATGTCCCAAAGAGAGGCTCACCTGTACCACTGAACTTCCGGACTCATGTAACACAGATTTT
  GACTGCAAGGAATACCAGAAGTGCTGCTTTTTTGCCTGTCAGAAGAAGTGCATGGATCCCTTTCAAGAAC
  CCTGCATGCTACCTGTGAGGCATGGAAACTGTAATCATGAGGCACAGCGCTGGCATTTTGACTTTAAAAA
  TTACCGCTGCACACCCTTCAAATACAGGGGCTGCGAAGGGAATGCCAACAACTTCTTAAATGAGGATGCC
  TGCAGAACGGCCTGCATGTTAATTGTTAAGGATGGACAATGCCCACTCTTCCCTTTCACTGAACGTAAGG
  AGTGTCCACCTTCATGTCACAGTGACATCGATTGTCCCCAGACAGACAAATGTTGTGAATCCAGGTGTGG
  CTTTGTTTGTGCCAGGGCCTGGACAGTCAAAAAAGGTTTCTGCCCACGCAAGCCCTTGCTATGTACCAAG
  ATTGATAAACCCAAGTGCCTGCAGGATGAGGAGTGCCCATTGGTGGAAAAGTGCTGCTCACATTGTGGAC
  TGAAATGTATGGACCCCAGACGTTGA
  
  
• Restriction Sites: Please inquire
• ACCN: NM_130896
• ORF Size: 726 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_130896.1, NP_570966.1
• RefSeq Size: 1069
• RefSeq ORF: 726
• Locus ID: 90199
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains a Kunitz-inhibitor domain, in addition to three WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode the same protein. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (a) represents the shorter transcript. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.