Neurexin II alpha (NRXN2) (NM_138734) Human Untagged Clone

CAT#: SC306071

NRXN2 (untagged)-Human neurexin 2 (NRXN2), transcript variant beta

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NRXN2
• Synonyms: FLJ40892; KIAA0921
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_138734 edited
  CCGGGCCGAAATGCCCCCCGGGGGGAGCGGGCCGGGGGGGTGCCCGCGCCGCCCCCCGGC
  CCTGGCTGGGCCCCTGCCGCCGCCTCCACCGCCGCCGCCGCCACCTCTGCTGCCGCTGTT
  GCCGCTGTTGCTGCTGTTGCTGCTGGGGGCGGCCGAGGGGGCCCGGGTCTCCTCCAGCCT
  CAGCACCACCCACCACGTCCACCACTTCCACAGCAAGCACGGCACCGTGCCCATCGCCAT
  CAACCGCATGCCCTTCCTCACCCGCGGCGGCCACGCCGGGACCACATACATCTTTGGGAA
  GGGGGGAGCGCTCATCACCTACACGTGGCCCCCCAATGACAGGCCCAGCACGAGGATGGA
  TCGCCTGGCCGTGGGCTTCAGCACCCACCAGCGGAGCGCTGTGCTGGTGCGGGTGGACAG
  CGCCTCCGGCCTTGGAGACTACCTGCAGCTGCACATCGACCAGGGCACCGTGGGGGTGAT
  CTTTAACGTGGGCACGGACGACATTACCATCGACGAGCCCAACGCCATAGTAAGCGACGG
  CAAATACCACGTGGTGCGCTTCACTCGAAGCGGCGGCAACGCCACCCTGCAGGTGGACAG
  CTGGCCGGTCAACGAGCGGTACCCGGCAGGAAACTTTGATAACGAGCGCCTGGCGATTGC
  TAGACAGAGAATCCCCTACCGGCTTGGTCGAGTAGTAGATGAGTGGCTGCTCGACAAAGG
  CCGCCAGCTGACCATCTTCAACAGCCAGGCTGCCATCAAGATCGGGGGCCGGGATCAGGG
  CCGCCCCTTCCAGGGCCAGGTGTCCGGCCTCTACTACAATGGGCTCAAGGTGCTGGCGCT
  GGCCGCCGAGAGCGACCCCAATGTGCGGACTGAGGGTCACCTGCGCCTGGTGGGGGAGGG
  GCCGTCCGTGCTGCTCAGTGCGGAGACCACGGCCACCACCCTGCTGGCTGACATGGCCAC
  CACCATCATGGAGACTACCACCACCATGGCCACTACCACCACGCGCCGGGGCCGCTCCCC
  CACACTGAGGGACAGCACCACCCAGAACACAGATGACCTGCTGGTGGCCTCTGCTGAGTG
  TCCAAGCGATGATGAGGACCTGGAGGAGTGTGAGCCCAGTACTGGAGGAGAGTTAATATT
  GCCCATTATCACGGAGGACTCCTTAGACCCCCCTCCCGTGGCCACCCGATCCCCCTTCGT
  GCCCCCGCCCCCTACCTTCTACCCCTTCCTCACGGGAGTGGGCGCCACCCAAGACACGCT
  GCCCCCGCCCGCCGCGCGCCGCCCGCCCTCTGGGGGCCCGTGCCAGGCCGAGCGGGACGA
  CAGCGACTGCGAGGAGCCCATCGAGGCCTCGGGCTTCGCCTCCGGGGAGGTCTTTGACTC
  CAGCCTCCCCCCCACGGACGACGAGGACTTTTACACCACCTTTCCCCTGGTCACGGACCG
  CACCACCCTCCTGTCACCCCGCAAACCCGCTCCCCGGCCCAACCTCAGGACAGATGGGGC
  CACGGGCGCCCCTGGGGTGCTGTTTGCCCCCTCCGCCCCGGCCCCCAACCTGCCGGCGGG
  CAAAATGAACCACCGAGACCCGCTTCAGCCCTTGCTGGAGAACCCGCCCTTGGGGCCCGG
  GGCCCCCACGTCCTTTGAGCCGCGGAGGCCCCCTCCCCTGCGCCCCGGCGTGACCTCAGC
  CCCCGGCTTCCCCCATCTGCCCACAGCCAACCCCACAGGGCCTGGGGAGCGGGGCCCGCC
  GGGCGCAGTGGAGGTGATCCGGGAGTCCAGCAGCACCACGGGCATGGTGGTGGGCATTGT
  GGCGGCGGCGGCGCTCTGCATCCTCATCCTCCTCTACGCCATGTATAAGTACCGCAATCG
  TGATGAGGGCTCCTACCAGGTGGACCAGAGCCGAAACTACATCAGTAACTCGGCCCAGAG
  CAATGGGGCGGTGGTGAAAGAGAAGGCCCCGGCTGCCCCCAAGACGCCCAGCAAGGCCAA
  GAAGAACAAAGACAAGGAGTATTATGTCTGAGCCCCCGGCACTGCGCCCCACTGCCAGCT
  GCCCCTCCTGGGAGGGCCCGGGAGGAGGGTGCCACCCTCTCCCTGCCAGGGGCCTGGGGA
  CCCTCTCCCTGGCTGCCTCAGGCTTCTCTTACGAAGAGGAAACGCAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_138734
• ORF Size: 2001 bp
• Insert Size: 2300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: It is not a varient.

Reference Data

• RefSeq: NM_138734.1, NP_620063.1
• RefSeq Size: 3550
• RefSeq ORF: 2001
• Locus ID: 9379
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992). [provided by RefSeq, Jun 2010]
  Transcript Variant: This variant (beta) lacks most 5' exons and has an alternate exon at the 5' end, as compared to variant alpha-1. It encodes isoform beta which has a much shorter and different N-terminus than isoform alpha-1 (PMID: 12036300 and PMID: 11944992). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.